Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/Tad-HTH_37
Location 2125058..2125697 Replicon chromosome
Accession NC_011146
Organism Geobacter bemidjiensis Bem

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag GBEM_RS09175 Protein ID WP_012530262.1
Coordinates 2125058..2125396 (+) Length 113 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag GBEM_RS09180 Protein ID WP_012530263.1
Coordinates 2125386..2125697 (+) Length 104 a.a.

Genomic Context

GBEM_RS09170GBEM_RS09175GBEM_RS09180GBEM_RS09185GBEM_RS09190GBEM_RS09195GBEM_RS09200
Location: 2122707..2124971 (2265 bp)
Type: Others
Protein ID: WP_012530261.1
Location: 2125058..2125396 (339 bp)
Type: Toxin
Protein ID: WP_012530262.1
Location: 2125386..2125697 (312 bp)
Type: Antitoxin
Protein ID: WP_012530263.1
Location: 2125838..2127346 (1509 bp)
Type: Others
Protein ID: WP_012530264.1
Location: 2127346..2128260 (915 bp)
Type: Others
Protein ID: WP_012530265.1
Location: 2128272..2129222 (951 bp)
Type: Others
Protein ID: WP_012530266.1
Location: 2129225..2130538 (1314 bp)
Type: Others
Protein ID: WP_012530267.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
GBEM_RS091702122707..2124971+2265WP_012530261.1alpha-amylase-
GBEM_RS091752125058..2125396+339WP_012530262.1type II toxin-antitoxin system RelE/ParE family toxinToxin
GBEM_RS091802125386..2125697+312WP_012530263.1helix-turn-helix domain-containing proteinAntitoxin
GBEM_RS091852125838..2127346-1509WP_012530264.1hypothetical protein-
GBEM_RS091902127346..2128260-915WP_012530265.1type II secretion system F family protein-
GBEM_RS091952128272..2129222-951WP_012530266.1type II secretion system F family protein-
GBEM_RS092002129225..2130538-1314WP_012530267.1CpaF family protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-like

(17-105)

Antitoxin

Cro/C1-type helix-turn-helix domain

(41-96)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 12801.01 Da        Isoelectric Point: 8.9539

>T23034 WP_012530262.1 NC_011146:2125058-2125396 [Geobacter bemidjiensis Bem]
MVMVFRLSYYDEAVEVELDAWPVGLRAPFRALTIRMEEYGPNLGMPHTRALGNGLFEIRAKAEEGIGRAFFCTMVGRKII
ILHSFIKKTDKTPKRELDIALARQKEVFGNEL

Download         Length: 339 bp

>T23034 NC_011146:2125058-2125396 [Geobacter bemidjiensis Bem]
ATGGTCATGGTTTTCCGACTTTCATATTATGATGAAGCTGTCGAGGTTGAACTTGATGCTTGGCCAGTGGGGCTACGCGC
ACCTTTCCGGGCGTTGACCATACGTATGGAAGAATATGGGCCAAATTTGGGCATGCCGCATACTCGGGCATTAGGAAACG
GCCTCTTTGAAATACGCGCCAAAGCAGAAGAAGGAATCGGTAGAGCCTTTTTCTGCACCATGGTGGGGAGAAAGATCATA
ATTCTCCATAGCTTCATCAAAAAGACGGACAAGACACCAAAACGGGAACTAGACATAGCGCTTGCCCGTCAGAAGGAGGT
ATTTGGTAATGAGCTATAA

Antitoxin


Download         Length: 104 a.a.        Molecular weight: 11630.48 Da        Isoelectric Point: 8.5012

>AT23034 WP_012530263.1 NC_011146:2125386-2125697 [Geobacter bemidjiensis Bem]
MSYKPISYHPKKKLEQELQDPTFKQEWEALEDEFAALDVLLKARKAAGLTQEQVAAKMGVSQPSLARVEASLCSHRHSPS
LEMLRKYAAAVNCKLEIKLVPQH

Download         Length: 312 bp

>AT23034 NC_011146:2125386-2125697 [Geobacter bemidjiensis Bem]
ATGAGCTATAAACCGATTTCGTATCATCCCAAGAAAAAGCTGGAGCAAGAGCTTCAAGATCCGACTTTTAAGCAGGAATG
GGAAGCCTTGGAAGATGAATTTGCCGCGTTGGATGTCCTGCTTAAAGCACGTAAAGCAGCGGGGCTTACCCAGGAACAGG
TTGCCGCCAAGATGGGTGTGTCACAGCCATCGTTGGCAAGGGTTGAAGCGTCGCTTTGTTCTCACCGGCATTCTCCATCT
CTGGAAATGCTTCGCAAATATGCTGCGGCTGTTAATTGTAAACTTGAGATAAAGCTGGTGCCGCAGCACTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References