Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | I | Classification (family/domain) | hok-sok/- |
Location | 74384..74802 | Replicon | plasmid p1 |
Accession | NZ_CP090197 | ||
Organism | Escherichia coli strain YL3 |
Toxin (Protein)
Gene name | hok | Uniprot ID | - |
Locus tag | LXN07_RS24935 | Protein ID | WP_223412041.1 |
Coordinates | 74680..74802 (+) | Length | 41 a.a. |
Antitoxin (RNA)
Gene name | srnC | ||
Locus tag | - | ||
Coordinates | 74384..74588 (-) |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LXN07_RS24895 | 69609..69782 | - | 174 | Protein_83 | hypothetical protein | - |
LXN07_RS24900 | 70084..70605 | + | 522 | WP_012881138.1 | single-stranded DNA-binding protein | - |
LXN07_RS24905 | 70661..70894 | + | 234 | WP_000005971.1 | DUF905 domain-containing protein | - |
LXN07_RS24910 | 70958..72916 | + | 1959 | WP_257120052.1 | ParB/RepB/Spo0J family partition protein | - |
LXN07_RS24915 | 72971..73405 | + | 435 | WP_000845949.1 | conjugation system SOS inhibitor PsiB | - |
LXN07_RS24920 | 73402..74121 | + | 720 | WP_012881136.1 | plasmid SOS inhibition protein A | - |
LXN07_RS24925 | 74118..74432 | + | 315 | WP_000872086.1 | hypothetical protein | - |
- | 74381..74588 | + | 208 | NuclAT_0 | - | - |
- | 74381..74588 | + | 208 | NuclAT_0 | - | - |
- | 74381..74588 | + | 208 | NuclAT_0 | - | - |
- | 74381..74588 | + | 208 | NuclAT_0 | - | - |
- | 74384..74588 | - | 205 | - | - | Antitoxin |
LXN07_RS24930 | 74622..74735 | + | 114 | Protein_90 | DUF5431 family protein | - |
LXN07_RS24935 | 74680..74802 | + | 123 | WP_223412041.1 | Hok/Gef family protein | Toxin |
LXN07_RS24940 | 75103..75352 | - | 250 | Protein_92 | hypothetical protein | - |
LXN07_RS24945 | 75648..75971 | + | 324 | WP_000533253.1 | hypothetical protein | - |
LXN07_RS24950 | 76030..76272 | + | 243 | WP_000540588.1 | hypothetical protein | - |
LXN07_RS24955 | 76472..76624 | - | 153 | Protein_95 | hypothetical protein | - |
LXN07_RS24960 | 76737..78404 | - | 1668 | WP_117313998.1 | group II intron reverse transcriptase/maturase | - |
LXN07_RS24965 | 79133..79306 | - | 174 | Protein_97 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Conjugative plasmid | blaCTX-M-14 | - | 1..97598 | 97598 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 41 a.a. Molecular weight: 4560.33 Da Isoelectric Point: 8.2774
>T230214 WP_223412041.1 NZ_CP090197:74680-74802 [Escherichia coli]
IVCCTLLIFTHLTRNRLCEVRLKDGYREVTASLAYESSGK
IVCCTLLIFTHLTRNRLCEVRLKDGYREVTASLAYESSGK
Download Length: 123 bp
>T230214 NZ_CP124804:197143-197628 [Klebsiella variicola]
GTGGGAAGTTTAACAGCACCAGAACCTTTATCCAGCTTTCATCAGGTGGCAGAGTTCGTTTGCGGTGAAACTGTTCTGGA
TGACTGGTTAAAGCAGAAAGGCCTCAAAAACCAGGCTCTCGGAGCGGCCAGAACGTTTGTAGTGTGTAAGAAAGACACAA
AGCAAGTAGCCGGTTTTTACTCTCTGGCCACCGGGAGCGTCAACCATACAGAAGCGACAGGCAATCTTCGGCGTAACATG
CCAGATCCCATCCCTGTCATCATACTTGCCCGTCTTGCAGTCGATCTCTCTTTTCGCGGAAAAGGGCTTGGTGCTGATTT
ACTTCATGATGCAGTGCTTCGTTGCTATCGGGTTGCCGAGAATATTGGTGTACGTGCAATTATGGTTCACGCACTCACCG
AAGAAGCTAACAATTTCTACATTCACCATGGTTTCAAGCCATCACAAACTCAGCAACGGACATTATTCCTTAAACTGCCT
CAATAA
GTGGGAAGTTTAACAGCACCAGAACCTTTATCCAGCTTTCATCAGGTGGCAGAGTTCGTTTGCGGTGAAACTGTTCTGGA
TGACTGGTTAAAGCAGAAAGGCCTCAAAAACCAGGCTCTCGGAGCGGCCAGAACGTTTGTAGTGTGTAAGAAAGACACAA
AGCAAGTAGCCGGTTTTTACTCTCTGGCCACCGGGAGCGTCAACCATACAGAAGCGACAGGCAATCTTCGGCGTAACATG
CCAGATCCCATCCCTGTCATCATACTTGCCCGTCTTGCAGTCGATCTCTCTTTTCGCGGAAAAGGGCTTGGTGCTGATTT
ACTTCATGATGCAGTGCTTCGTTGCTATCGGGTTGCCGAGAATATTGGTGTACGTGCAATTATGGTTCACGCACTCACCG
AAGAAGCTAACAATTTCTACATTCACCATGGTTTCAAGCCATCACAAACTCAGCAACGGACATTATTCCTTAAACTGCCT
CAATAA
Antitoxin
Download Length: 205 bp
>AT230214 NZ_CP090197:c74588-74384 [Escherichia coli]
AGACATACAGGGGGCCTCGTGGGTTAATGAAAAATTAACTACGGGGCTTTCTGCCTTCTGCCACACAACACGGTAACAAA
CCACCTTCACGTCATGAGGCAGAAAGCCTCAAGCGCCGGGCACATCATAGCCCATATACCTGCGCACTGACCACACTCAC
TTTCCCTGAAAATAATCCGGTCGTTCAGCCAGTTCACGGGCAATC
AGACATACAGGGGGCCTCGTGGGTTAATGAAAAATTAACTACGGGGCTTTCTGCCTTCTGCCACACAACACGGTAACAAA
CCACCTTCACGTCATGAGGCAGAAAGCCTCAAGCGCCGGGCACATCATAGCCCATATACCTGCGCACTGACCACACTCAC
TTTCCCTGAAAATAATCCGGTCGTTCAGCCAGTTCACGGGCAATC
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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