Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 81615..82420 Replicon plasmid unnamed8
Accession NZ_CP090160
Organism Roseivivax marinus strain TCYB24

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag LVO79_RS21650 Protein ID WP_240094645.1
Coordinates 81941..82420 (+) Length 160 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag LVO79_RS21645 Protein ID WP_240094644.1
Coordinates 81615..81944 (+) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LVO79_RS21615 (LVO79_21615) 77121..77843 - 723 WP_240094639.1 hypothetical protein -
LVO79_RS21620 (LVO79_21620) 77848..79071 - 1224 WP_240094640.1 nucleotidyltransferase -
LVO79_RS21625 (LVO79_21625) 79247..79804 + 558 WP_240094641.1 hypothetical protein -
LVO79_RS21630 (LVO79_21630) 79794..80210 + 417 WP_240094642.1 hypothetical protein -
LVO79_RS21635 (LVO79_21635) 80207..80992 + 786 WP_240094643.1 ImmA/IrrE family metallo-endopeptidase -
LVO79_RS21640 (LVO79_21640) 81024..81452 - 429 Protein_88 hypothetical protein -
LVO79_RS21645 (LVO79_21645) 81615..81944 + 330 WP_240094644.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
LVO79_RS21650 (LVO79_21650) 81941..82420 + 480 WP_240094645.1 type II toxin-antitoxin system YhaV family toxin Toxin
LVO79_RS21655 (LVO79_21655) 82458..83057 + 600 WP_240094646.1 hypothetical protein -
LVO79_RS21660 (LVO79_21660) 83072..83560 - 489 WP_240094647.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..136103 136103


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(18-153)

Antitoxin

PrlF antitoxin

(10-109)


Sequences

Toxin        


Download         Length: 160 a.a.        Molecular weight: 18072.59 Da        Isoelectric Point: 9.7332

>T230155 WP_240094645.1 NZ_CP090160:81941-82420 [Roseivivax marinus]
MSEAQVSGALVVKGWTLLQDPAFAEGYEDLVATVEGLREKHPETYRKKAPTKILAAIEKLTKEVIPADPTSSAFDLGNTI
GPEHRAWKRAKFLQQFRLFFRYDTKSRIIIYGWVNDEKTKRAYGSKTDAYRVFQKRLAAGDPPTDWDDLIKRAAPVDQQ

Download         Length: 480 bp

>T230155 NZ_CP124740:c146473-146324 [Escherichia coli O157:H7 str. EDL933]
ATGAGATATGACAATGTTAAACCATGTCCATTTTGTGGTTGTCCATCAGTAACGGTGAAAGCCATTTCAGGATATTACCG
AGCGAAGTGTAACGGATGCGAATCCCGAACCGGTTATGGTGGAAGTGAAAAAGAAGCACTCGAACGATGA

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12126.71 Da        Isoelectric Point: 4.6092

>AT230155 WP_240094644.1 NZ_CP090160:81615-81944 [Roseivivax marinus]
MSDVQAPRFEATLTDKYQNTVPAAVRKALHLGKRDKIAYVIRGGQVILEKAETKDDQVDPAVQAFLGFLEREMVNNPQRL
KPFGGETSRRAAELVEGMDVDLDAPLDDE

Download         Length: 330 bp

>AT230155 NZ_CP124740:146102-146280 [Escherichia coli O157:H7 str. EDL933]
GAGGACTGAAGTTTCTCGCAATTAAAATTTATCAGTTTTACTTTCTGCTCTCTGGAAACGCCTGCTTCTTTTTTACCTGA
GAGCATTTTTTCGCATTCTGATTTCGTTAGTTTAGATTTTGAATATCTTGTCCAGTTAGTAGGAGTGCCACCTTCCTTTT
CAATAGTGGCGGTAATTTT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References