Detailed information of TA system TA229999

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): yefM-yoeB (relBE)/YoeB-YefM
• Location: 2831790..2832319
• Replicon: chromosome
• Accession: NZ_CP090066
• Organism: Aurantimonas sp. HBX-1

Toxin (Protein)

• Gene name: yoeB
• Uniprot ID: -
• Locus tag: LXB15_RS13460
• Protein ID: WP_233948937.1
• Coordinates: 2831790..2832056 (-)
• Length: 89 a.a.

Antitoxin (Protein)

• Gene name: yefM
• Uniprot ID: -
• Locus tag: LXB15_RS13465
• Protein ID: WP_233948938.1
• Coordinates: 2832053..2832319 (-)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LXB15_RS13450 (LXB15_13450)	2830400..2831092	+	693	WP_233948935.1	Uma2 family endonuclease	-
LXB15_RS13455 (LXB15_13455)	2831243..2831734	+	492	WP_233948936.1	ribbon-helix-helix domain-containing protein	-
LXB15_RS13460 (LXB15_13460)	2831790..2832056	-	267	WP_233948937.1	Txe/YoeB family addiction module toxin	Toxin
LXB15_RS13465 (LXB15_13465)	2832053..2832319	-	267	WP_233948938.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
LXB15_RS13470 (LXB15_13470)	2832637..2833575	-	939	WP_233948939.1	hypothetical protein	-
LXB15_RS13475 (LXB15_13475)	2833575..2833970	-	396	WP_233948940.1	hypothetical protein	-
LXB15_RS13480 (LXB15_13480)	2834484..2835437	+	954	WP_233948941.1	tripartite tricarboxylate transporter substrate binding protein	-
LXB15_RS13485 (LXB15_13485)	2835437..2835925	+	489	WP_233948942.1	tripartite tricarboxylate transporter TctB family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (1-86)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (16-72)

Sequences

Toxin

Protein

• Length: 89 a.a.
• Molecular weight: 10501.11 Da
• Isoelectric Point: 10.0143

>T229999 WP_233948937.1 NZ_CP090066:c2832056-2831790 [Aurantimonas sp. HBX-1]
MKLLWAEQAWSDYLHFQKVDEKIRDRINELIKETRRTLLRGIGKPEPLKGDLTGWWSRRITGDHRLVCRVAGKDDDQRLE
IAACRYKH

Nucleotide

• Length: 267 bp

>T229999 NZ_CP124658:c150979-150698 [Pseudomonas aeruginosa]
ATGAGCCTGAAGTGGACCCGCAAGGCGGCCGCCGACCTGGACGCCATCTACGACCATTACGTCGTGCTGATCGGCCCGGA
AAAAGCCCTGAAAGCCGTCCAGGACATCGTCGAGCAGGTGAAACCGCTGCAGCAGGTAGCCAACCAGGGGGCAGGGCGGC
CCAGCGAGGTGCCAGGCGTACGCACCCTGACCCTGGAGCGCTGGCCGTTCAGCGCCCCTTTTCGGGTAAAAGGCAAGGAA
ATCCAGATTTTGCGCATCGACAGGGTCGAAATTACCCCCTGA

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 9557.60 Da
• Isoelectric Point: 4.6364

>AT229999 WP_233948938.1 NZ_CP090066:c2832319-2832053 [Aurantimonas sp. HBX-1]
MADRFHAVAGYPAGHFEELIRSRAPLLVTRQGRESAVLISASEWEGVQETLHLLGSRNNADKLFGAIAELDAGRGVERDP
TVDAEDAQ

Nucleotide

• Length: 267 bp

>AT229999 NZ_CP124658:c151203-150976 [Pseudomonas aeruginosa]
ATGAGCACCGTAGTCTCGTTCCGCGCCGATGACGCCCTGGTCGCGGCCCTCGACGAACTGGCCCGCGCCACCCACCGCGA
CCGCCCGTATCACCTGCGGCAGGCGCTCGCGCAGTACCTGGAAAGGCAGCAGTGGCAGGTCGCTGCCATCGATGAAGGCT
TGGCCGATGCCAATGCCGGTCGCCTGCTGGAACACACCGAGATCGAGAAGCGCTGGGGGCTGCAATGA