Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 170329..170845 Replicon plasmid p1
Accession NZ_CP090023
Organism Cereibacter azotoformans strain SY5

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag LV780_RS20170 Protein ID WP_011910969.1
Coordinates 170579..170845 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LV780_RS20165 Protein ID WP_011910970.1
Coordinates 170329..170598 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LV780_RS20145 (LV780_20145) 165820..167157 + 1338 WP_011910974.1 ferric reductase-like transmembrane domain-containing protein -
LV780_RS20150 (LV780_20150) 167332..167442 + 111 WP_233864294.1 helix-turn-helix domain-containing protein -
LV780_RS20155 (LV780_20155) 167535..168740 - 1206 WP_011910972.1 sodium/glutamate symporter -
LV780_RS20160 (LV780_20160) 169138..169725 + 588 Protein_146 Tn3 family transposase -
LV780_RS20165 (LV780_20165) 170329..170598 + 270 WP_011910970.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LV780_RS20170 (LV780_20170) 170579..170845 + 267 WP_011910969.1 Txe/YoeB family addiction module toxin Toxin
LV780_RS20175 (LV780_20175) 171103..171327 + 225 WP_108222325.1 transcriptional regulator/antitoxin MazE -
LV780_RS20180 (LV780_20180) 171324..171728 + 405 WP_011910966.1 type II toxin-antitoxin system death-on-curing family toxin -
LV780_RS20185 (LV780_20185) 171831..171884 - 54 Protein_151 hypothetical protein -
LV780_RS20190 (LV780_20190) 172103..172282 + 180 WP_101339531.1 hypothetical protein -
LV780_RS20195 (LV780_20195) 172401..172565 + 165 WP_180325088.1 hypothetical protein -
LV780_RS20200 (LV780_20200) 172587..173510 - 924 WP_117345223.1 DMT family transporter -
LV780_RS20205 (LV780_20205) 173630..174433 - 804 WP_117345224.1 AraC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..298439 298439


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-88)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10329.63 Da        Isoelectric Point: 9.5467

>T229918 WP_011910969.1 NZ_CP090023:170579-170845 [Cereibacter azotoformans]
MKLIFSDRAWDDYHHWHQTDATIFERLNGLIKEASRQPFRGTGKPEPLKGDLSGWWSRRLTGEHRLVYRVSGSGVTQALE
IAQCRYHY

Download         Length: 267 bp

>T229918 NZ_CP124638:1782728-1783483 [Pseudomonas aeruginosa]
GTGAGCGAGATCTGGCGACAGTGCAAGGGTGAGCGGCATGTCCGACCGCTCCAGGGGCGGCTGGTGCGGTTGGTGGAGAG
CCAGGAGCAGGTGGCGACCCTGCAATTGGTCGACACCCTGGAAGAACAGGCGTTGCTCGAGGAACTGCTCGAGTCGAGCA
AGCCGCCGGTGCCGGCGGATGCCGAGCCATTGCATTACCTGTTGAAGACCCCGTTCCGTTATCCGCCCTTGCGTTGGGGG
TCGCGGTTTGGCCGTCGTCACGAGCCAAGCCTGTTCTACGCCGCGTTGAAGCTGGAAACGGCCATGGCCGAAAGCGCGTA
TTACCGTTGTGTCCTGTGGAGTGGCATGGCGGTGCCGCCACCGAGCGGGAGGATTCTGTCCGAGCACGCTTCGTTCGAGG
CGGGCTGGAAGGTGGAGCGGGGAATCCGTCTGCAGGCGCCGCCTTTCTCCGATCACGAGGCTGCGCTGACCGACATCGCC
GACTACCGCGCTCCCCAGGAACTGGGGAGTGCCATGCGCAGCGCCGGGGTGCAGGCATTCGAATACCGTTCGGCGCGTTG
CCCGGAGCGCGGCTGCAATGTCGCCCTGTTCACGCCCGCGGCCTTCACCGAAAAGCGTCCTCGCAACCTGACGCCCTGGC
TGTGCGAAACCACGGCCGGTTACGTGGCCTTCAAGCCGGCGCATGTGCCGGGGTCGCCGAAAATCTTCTCCTGGGAGCTG
TTCCTGGTGGACGGAAAGTTGCCGCATCCGGCGTGA

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9841.06 Da        Isoelectric Point: 4.5069

>AT229918 WP_011910970.1 NZ_CP090023:170329-170598 [Cereibacter azotoformans]
MNILTYTDARKHLKSVMDSAIHDKEETVITRAGQEAVVVVGKEEWDAIQATLHLLSSPVNAARLRESIAQLNAGQGTERD
LIEDETDIL

Download         Length: 270 bp

>AT229918 NZ_CP124638:1782225-1782593 [Pseudomonas aeruginosa]
ATGAGCGCTCTCATCAAGGAACGTCCCAGCGCCGATGCTGTCCTGGCCAAGGCCGTCCTGGCCGCGCGCGAGCAATTGGG
GCTGACGCAGCTCGAACTGGCCGGCATCGTCGGCGTCGATCGCAGCGCCATCAGCCGCTGGAAGACCCAGGGCCTGCGGG
TGGACAGCAAGACCGGCGAGCTGGCTCTGCTGCTGGTGCGGGTCTATCGCGCACTGTATGCCCTGTTCGGCGGGCAGCAG
GAGGACATGCGCCACTTCCTGCGCACTCCCAACCATCACCTGGCGGGCGAGCCGCTGGCACTGATGGGACAGGTGCAGGG
CCTGGTTCATGTGCTGGAATACCTCGATGCGATCCGCGGCAAGGTCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References