Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 1075072..1075523 Replicon chromosome
Accession NZ_CP090000
Organism Xanthomonas translucens strain B1FA

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag LZE81_RS04925 Protein ID WP_230939940.1
Coordinates 1075072..1075221 (+) Length 50 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag LZE81_RS04930 Protein ID WP_196480047.1
Coordinates 1075341..1075523 (+) Length 61 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LZE81_RS04880 (LZE81_04880) 1070186..1070854 + 669 WP_003479795.1 dTMP kinase -
LZE81_RS04885 (LZE81_04885) 1070851..1071828 + 978 WP_003479796.1 DNA polymerase III subunit delta' -
LZE81_RS04890 (LZE81_04890) 1071825..1072178 + 354 WP_003479797.1 PilZ domain-containing protein -
LZE81_RS04900 (LZE81_04900) 1072469..1072726 - 258 WP_058195736.1 Txe/YoeB family addiction module toxin -
LZE81_RS04905 (LZE81_04905) 1072723..1072974 - 252 WP_003468816.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
LZE81_RS04910 (LZE81_04910) 1073083..1073616 + 534 Protein_958 endonuclease -
LZE81_RS04915 (LZE81_04915) 1073613..1074335 - 723 WP_058360631.1 helix-turn-helix transcriptional regulator -
LZE81_RS04920 (LZE81_04920) 1074459..1074902 + 444 WP_058360632.1 nuclear transport factor 2 family protein -
LZE81_RS04925 (LZE81_04925) 1075072..1075221 + 150 WP_230939940.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LZE81_RS04930 (LZE81_04930) 1075341..1075523 + 183 WP_196480047.1 hypothetical protein Antitoxin
LZE81_RS20010 1076371..1076493 + 123 WP_267919419.1 hypothetical protein -
LZE81_RS04940 (LZE81_04940) 1076649..1079099 - 2451 WP_081049173.1 DEAD/DEAH box helicase family protein -
LZE81_RS04945 (LZE81_04945) 1079086..1079640 - 555 WP_058360994.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(5-92)

Antitoxin

Cro/C1-type helix-turn-helix domain

(20-69)


Sequences

Toxin        


Download         Length: 50 a.a.        Molecular weight: 5326.12 Da        Isoelectric Point: 8.5858

>T229894 WP_230939940.1 NZ_CP090000:1075072-1075221 [Xanthomonas translucens]
MDDETYAKLQVLLQENLEVGDLIEGTGGLRKVRVAAKGHGKRGGARVIY

Download         Length: 150 bp

>T229894 NZ_CP124626:2208748-2209026 [Pseudomonas aeruginosa]
ATGATTCTGACCTTTCGCTGCGACGAGACTCGTCAGCTTTTTGAGACGGGTCTTTCGAGGCGGTGGGGAGCGATCCTCAC
AGTCGCTACGCGTAAGCTCGCAATGCTTCATGCGGCTACGGAGCTTCGAGACTTGCGCTCTCCACCTGGAAACCGGTTGG
AGCCGTTGCAGGGAAAGCGGGCGGGCCAACATAGCATCAGGATCAATGACCAGTGGCGTGTCTGTTTCGTCTGGACGGAT
GCGGGTCCCGAAGAAGTCGAAATAGTTGATTACCACTGA

Antitoxin


Download         Length: 61 a.a.        Molecular weight: 6745.77 Da        Isoelectric Point: 8.9195

>AT229894 WP_196480047.1 NZ_CP090000:1075341-1075523 [Xanthomonas translucens]
MSKFFEALMESVQQMDEIVRGERAPSREFHVDAIQVKQVRLPASPSLRAANKTMEVAAGR

Download         Length: 183 bp

>AT229894 NZ_CP124626:2209038-2209343 [Pseudomonas aeruginosa]
ATGGCTACCAATGGTATGCGCCCCATCCATCCTGGGGAAATATTGCGCGATGAGTTTCTGATGGAGTTGGATATCTCTCC
AGCTGCTCTAGCACGCGCTTTGAAAGTCTCCGCTCCGACAGTGAATGATATCGTTCGTGAGCAGCGTGGTATCTCCGCAG
ATATGGCGATTCGTCTGGGGCGTTACTTTGATACGTCCGCTCAGTTCTGGATGAATCTCCAGAGTGAGTATTCGTTAGCA
ACTGCTTATGCGGCGAATGGCGAGCAGATCGAACATGAGATTGAGCCGCTGCTTGCTCAGGGATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References