Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 5790418..5790995 Replicon chromosome
Accession NZ_CP089980
Organism Fulvivirga sp. SW1-E11

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag LVD15_RS24330 Protein ID WP_233777788.1
Coordinates 5790714..5790995 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name graA Uniprot ID -
Locus tag LVD15_RS24325 Protein ID WP_233777787.1
Coordinates 5790418..5790714 (-) Length 99 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LVD15_RS24310 (LVD15_24310) 5786044..5788446 - 2403 WP_233777784.1 TonB-dependent receptor -
LVD15_RS24315 (LVD15_24315) 5788576..5789565 + 990 WP_233777785.1 AraC family transcriptional regulator -
LVD15_RS24320 (LVD15_24320) 5789620..5790117 - 498 WP_233777786.1 DUF4468 domain-containing protein -
LVD15_RS24325 (LVD15_24325) 5790418..5790714 - 297 WP_233777787.1 HigA family addiction module antitoxin Antitoxin
LVD15_RS24330 (LVD15_24330) 5790714..5790995 - 282 WP_233777788.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LVD15_RS24335 (LVD15_24335) 5791310..5792107 - 798 WP_233777790.1 hypothetical protein -
LVD15_RS24340 (LVD15_24340) 5792315..5792800 - 486 WP_233777791.1 hypothetical protein -
LVD15_RS24345 (LVD15_24345) 5793094..5795604 - 2511 WP_233777792.1 zinc-dependent metalloprotease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(11-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(16-66)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11042.65 Da        Isoelectric Point: 8.9359

>T229836 WP_233777788.1 NZ_CP089980:c5790995-5790714 [Fulvivirga sp. SW1-E11]
MIESFGCKHTEKVWNGVWTKKWSDEVANNALRKMFMINAAGDIQDLKIPPSNRLHKLKGNMKEYWAISINDQWRIIFQWS
NTNAYDVQIIDYH

Download         Length: 282 bp

>T229836 NZ_CP124536:c119743-119348 [Fuscovulum sp. YMD61]
ATGAGCGCTGAGTTCGCGGACACGAATGTCGTTCTTTACCTGCTCGACGATGGCCCGAAGGCCGATCGCGCCGAGGTTAT
CCTGGGGCAGGGGCCCCGGATCAGCGTTCAGGTCCTGAACGAGACGCTGGTGAACTGTCGCCGCAAGGCTGGCATGAGCT
GGGAGGAAGCAGGGGCGTTTCTTGAGAGCATTCGTGCCTTGTGCCCCGTCGAAGACCTGACCATTCAGACCCACGACGTC
GGCCGCGCCTTGGCGGAACGCTACAGCTTCTCGATCTACGACGCCATGATCATGGCCAGCGCTTTGGTTGCGGGCTGCAC
CACGCTGTGGAGCGAGGACATGCAAGATGGCCTGCTGGTCGAAGGCCAGCTTCGCATCATCAACCCTTTTGCGTGA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11517.13 Da        Isoelectric Point: 7.1651

>AT229836 WP_233777787.1 NZ_CP089980:c5790714-5790418 [Fulvivirga sp. SW1-E11]
MLKNNIHPGEILKYEFLDPMNLSSYKLSKELGIQQTRISQIIKGKRSVTADTAIRLSKFFGTTEEFWMNLQCEYDLRNAH
SEKDNEFNKIQKFEIDQA

Download         Length: 297 bp

>AT229836 NZ_CP124536:c119960-119733 [Fuscovulum sp. YMD61]
ATGCAGGTCGCAAAATGGGGCAACTCGCTTGCCGTCCGTTTACCCGCTGAGCTTGTCCGGGAACTTGGCCTCAAGGAAGG
CGATCAGATCGACCTGGTCAAGGACGACGGCCAGGTCAGAGTCCGTCGTCTGGCGCGCGCGGATGAGGTGCTGACGGGTC
TGCGCCGCTTCCGGGGCAAGCTGCCCGCTGCGGGACGCCTGAGCCGCGATGACGCGCATGAGCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References