Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 5790418..5790995 Replicon chromosome
Accession NZ_CP089980
Organism Fulvivirga sp. SW1-E11

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag LVD15_RS24330 Protein ID WP_233777788.1
Coordinates 5790714..5790995 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name graA Uniprot ID -
Locus tag LVD15_RS24325 Protein ID WP_233777787.1
Coordinates 5790418..5790714 (-) Length 99 a.a.

Genomic Context

LVD15_RS24315LVD15_RS24310LVD15_RS24320LVD15_RS24325LVD15_RS24330LVD15_RS24335LVD15_RS24340LVD15_RS24345
Location: 5788576..5789565 (990 bp)
Type: Others
Protein ID: WP_233777785.1
Location: 5786044..5788446 (2403 bp)
Type: Others
Protein ID: WP_233777784.1
Location: 5789620..5790117 (498 bp)
Type: Others
Protein ID: WP_233777786.1
Location: 5790418..5790714 (297 bp)
Type: Antitoxin
Protein ID: WP_233777787.1
Location: 5790714..5790995 (282 bp)
Type: Toxin
Protein ID: WP_233777788.1
Location: 5791310..5792107 (798 bp)
Type: Others
Protein ID: WP_233777790.1
Location: 5792315..5792800 (486 bp)
Type: Others
Protein ID: WP_233777791.1
Location: 5793094..5795604 (2511 bp)
Type: Others
Protein ID: WP_233777792.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
LVD15_RS24310 (LVD15_24310)5786044..5788446-2403WP_233777784.1TonB-dependent receptor-
LVD15_RS24315 (LVD15_24315)5788576..5789565+990WP_233777785.1AraC family transcriptional regulator-
LVD15_RS24320 (LVD15_24320)5789620..5790117-498WP_233777786.1DUF4468 domain-containing protein-
LVD15_RS24325 (LVD15_24325)5790418..5790714-297WP_233777787.1HigA family addiction module antitoxinAntitoxin
LVD15_RS24330 (LVD15_24330)5790714..5790995-282WP_233777788.1type II toxin-antitoxin system RelE/ParE family toxinToxin
LVD15_RS24335 (LVD15_24335)5791310..5792107-798WP_233777790.1hypothetical protein-
LVD15_RS24340 (LVD15_24340)5792315..5792800-486WP_233777791.1hypothetical protein-
LVD15_RS24345 (LVD15_24345)5793094..5795604-2511WP_233777792.1zinc-dependent metalloprotease-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(11-93)

Antitoxin

Cro/C1-type helix-turn-helix domain

(16-66)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 11042.65 Da        Isoelectric Point: 8.9359

>T229836 WP_233777788.1 NZ_CP089980:c5790995-5790714 [Fulvivirga sp. SW1-E11]
MIESFGCKHTEKVWNGVWTKKWSDEVANNALRKMFMINAAGDIQDLKIPPSNRLHKLKGNMKEYWAISINDQWRIIFQWS
NTNAYDVQIIDYH

Download         Length: 282 bp

>T229836 NZ_CP124536:c119743-119348 [Fuscovulum sp. YMD61]
ATGAGCGCTGAGTTCGCGGACACGAATGTCGTTCTTTACCTGCTCGACGATGGCCCGAAGGCCGATCGCGCCGAGGTTAT
CCTGGGGCAGGGGCCCCGGATCAGCGTTCAGGTCCTGAACGAGACGCTGGTGAACTGTCGCCGCAAGGCTGGCATGAGCT
GGGAGGAAGCAGGGGCGTTTCTTGAGAGCATTCGTGCCTTGTGCCCCGTCGAAGACCTGACCATTCAGACCCACGACGTC
GGCCGCGCCTTGGCGGAACGCTACAGCTTCTCGATCTACGACGCCATGATCATGGCCAGCGCTTTGGTTGCGGGCTGCAC
CACGCTGTGGAGCGAGGACATGCAAGATGGCCTGCTGGTCGAAGGCCAGCTTCGCATCATCAACCCTTTTGCGTGA

Antitoxin


Download         Length: 99 a.a.        Molecular weight: 11517.13 Da        Isoelectric Point: 7.1651

>AT229836 WP_233777787.1 NZ_CP089980:c5790714-5790418 [Fulvivirga sp. SW1-E11]
MLKNNIHPGEILKYEFLDPMNLSSYKLSKELGIQQTRISQIIKGKRSVTADTAIRLSKFFGTTEEFWMNLQCEYDLRNAH
SEKDNEFNKIQKFEIDQA

Download         Length: 297 bp

>AT229836 NZ_CP124536:c119960-119733 [Fuscovulum sp. YMD61]
ATGCAGGTCGCAAAATGGGGCAACTCGCTTGCCGTCCGTTTACCCGCTGAGCTTGTCCGGGAACTTGGCCTCAAGGAAGG
CGATCAGATCGACCTGGTCAAGGACGACGGCCAGGTCAGAGTCCGTCGTCTGGCGCGCGCGGATGAGGTGCTGACGGGTC
TGCGCCGCTTCCGGGGCAAGCTGCCCGCTGCGGGACGCCTGAGCCGCGATGACGCGCATGAGCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References