Detailed information of TA system TA022849

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): hok-sok/-
• Location: 1314848..1315073
• Replicon: chromosome
• Accession: NC_010658
• Organism: Shigella boydii CDC 3083-94

Toxin (Protein)

• Gene name: hokW
• Uniprot ID: -
• Locus tag: SBBS512_RS09135
• Protein ID: WP_000018429.1
• Coordinates: 1314861..1315073 (+)
• Length: 71 a.a.

Antitoxin (RNA)

Gene name	sokW
Locus tag	-
Coordinates	1314848..1314906 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
SBBS512_RS09100	1310179..1310460	+	282	WP_000391950.1	helix-turn-helix domain-containing protein	-
SBBS512_RS09105	1310444..1310869	+	426	WP_000693888.1	Rha family transcriptional regulator	-
SBBS512_RS09110	1310892..1311854	+	963	WP_000095673.1	helix-turn-helix domain-containing protein	-
SBBS512_RS09115	1311861..1312607	+	747	WP_000788950.1	ATP-binding protein	-
SBBS512_RS09120	1312629..1313399	+	771	WP_000450998.1	DUF1627 domain-containing protein	-
SBBS512_RS09125	1313415..1313840	+	426	WP_001151161.1	DUF977 family protein	-
SBBS512_RS09130	1314015..1314680	+	666	WP_000150294.1	epoxyqueuosine reductase QueH	-
-	1314848..1314906	-	59	-	-	Antitoxin
SBBS512_RS09135	1314861..1315073	+	213	WP_000018429.1	type I toxin-antitoxin system Hok family toxin	Toxin
SBBS512_RS28875	1315241..1315513	+	273	WP_001329966.1	hypothetical protein	-
SBBS512_RS09145	1315587..1316570	+	984	WP_162766644.1	DUF968 domain-containing protein	-
SBBS512_RS09150	1316571..1316951	+	381	WP_000140012.1	RusA family crossover junction endodeoxyribonuclease	-
SBBS512_RS09155	1316948..1317769	+	822	WP_000762914.1	antitermination protein	-
SBBS512_RS09160	1317996..1318236	+	241	Protein_1347	hypothetical protein	-
SBBS512_RS09165	1318344..1319393	+	1050	WP_000935515.1	site-specific DNA-methyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	1287491..1353041	65550

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Hok/gef cell toxic protein (25-66)

Sequences

Toxin

Protein

• Length: 71 a.a.
• Molecular weight: 7808.38 Da
• Isoelectric Point: 9.7376

>T22849 WP_000018429.1 NC_010658:1314861-1315073 [Shigella boydii CDC 3083-94]
MSHKCRLASYVPKGKGKQAMKQQKAMLIALIVICLTVIVTALVTRKDLCEVRLRTGQTEVAVFTAYEPEE

Nucleotide

• Length: 213 bp

>T22849 NC_010658:1314861-1315073 [Shigella boydii CDC 3083-94]
ATGTCTCACAAATGTAGGTTAGCCTCTTACGTGCCGAAAGGCAAGGGGAAGCAGGCTATGAAGCAGCAAAAGGCGATGTT
AATCGCCCTGATCGTCATCTGTTTAACCGTCATAGTGACGGCACTGGTAACGAGGAAAGACCTCTGCGAGGTACGACTCC
GAACCGGCCAGACGGAGGTCGCTGTCTTCACAGCTTACGAACCTGAGGAGTAA

Antitoxin

Nucleotide

• Length: 59 bp

>AT22849 NC_010658:c1314906-1314848 [Shigella boydii CDC 3083-94]
CCTTGCCTTTCGGCACGTAAGAGGCTAACCTACATTTGTGAGACATAGATTGGGCCTCA

Structures

Antitoxin