Detailed information of TA system TA228382

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprG-sprF/-
• Location: 2630025..2630303
• Replicon: chromosome
• Accession: NZ_CP089586
• Organism: Staphylococcus aureus strain E1185_IV_ST12

Toxin (Protein)

• Gene name: SprG3
• Uniprot ID: Q2FWA7
• Locus tag: LUU82_RS13070
• Protein ID: WP_001802298.1
• Coordinates: 2630025..2630129 (+)
• Length: 35 a.a.

Antitoxin (RNA)

Gene name	SprF3
Locus tag	-
Coordinates	2630125..2630303 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LUU82_RS13055	2626822..2627604	+	783	WP_000908175.1	ABC transporter ATP-binding protein	-
LUU82_RS13060	2627672..2628529	+	858	WP_000370925.1	Cof-type HAD-IIB family hydrolase	-
LUU82_RS13065	2629187..2629345	-	159	WP_001792784.1	hypothetical protein	-
LUU82_RS13070	2630025..2630129	+	105	WP_001802298.1	hypothetical protein	Toxin
-	2630125..2630303	-	179	-	-	Antitoxin
LUU82_RS13080	2630571..2631662	-	1092	WP_000495682.1	hypothetical protein	-
LUU82_RS13085	2631928..2632908	-	981	WP_000019744.1	CDF family zinc efflux transporter CzrB	-
LUU82_RS13090	2632910..2633230	-	321	WP_000003759.1	Zn(II)-responsive metalloregulatory transcriptional repressor CzrA	-
LUU82_RS13095	2633382..2634047	+	666	WP_001024095.1	SDR family oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 35 a.a.
• Molecular weight: 3906.77 Da
• Isoelectric Point: 5.5724

>T228382 WP_001802298.1 NZ_CP089586:2630025-2630129 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK

Nucleotide

• Length: 105 bp

>T228382 NZ_CP123897:2353055-2353438 [Methylomonas sp. UP202]
ATGATATTGGTCGATACCTCGGTTTGGATTGACCATTTCAAAAATCGCAACGAAGACCTGGTGCGTTTGCTCGTTACCGA
TTCGGCGTTGATTCACCCGCTGATTGTTGCCGAATTGGCTTGCGGTACGCCGCCCGCGCCGAGAACTCAAACCCTGAACA
ACCTCCGCCAGTTAAGGTGCTGCAATCAAGCCGGTTTGCAGGAAGTGGAAGACTTTATCGAGCGTGAAGCGCTATATGGC
TTGGGTTGCGGGCTAATCGATTTGCAGTTGCTGGCCTCGGTTTTGATCACGCCCGGTGCAAAGCTGTGGACGTTGGACAA
GCGGTTGGCGAAACTTGCCGAGCGGTTTGGTGTGGCTTATCAAGCTTCGCCGACTACGAATTGA

Antitoxin

Nucleotide

• Length: 179 bp

>AT228382 NZ_CP089586:c2630303-2630125 [Staphylococcus aureus]
GTGTTAAAATATATTTGTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGG
AAACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCA
AAGCGAATAGAAGGTTATT

Structures

Toxin

• AlphaFold DB: A0A2I7Y9L9

Antitoxin