Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | mqsRA (relBE)/MqsR-MqsA |
| Location | 458102..458808 | Replicon | chromosome |
| Accession | NC_010577 | ||
| Organism | Xylella fastidiosa M23 | ||
Toxin (Protein)
| Gene name | mqsR | Uniprot ID | Q87EE2 |
| Locus tag | XFASM23_RS01940 | Protein ID | WP_004090696.1 |
| Coordinates | 458102..458404 (+) | Length | 101 a.a. |
Antitoxin (Protein)
| Gene name | mqsA | Uniprot ID | Q87EE1 |
| Locus tag | XFASM23_RS01945 | Protein ID | WP_004090697.1 |
| Coordinates | 458407..458808 (+) | Length | 134 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| XFASM23_RS01905 | 453870..454589 | - | 720 | Protein_350 | phage late control D family protein | - |
| XFASM23_RS01910 | 454489..455460 | - | 972 | WP_011097609.1 | hypothetical protein | - |
| XFASM23_RS01915 | 455468..456025 | - | 558 | WP_011097610.1 | phage tail protein I | - |
| XFASM23_RS01920 | 456018..456911 | - | 894 | WP_011097611.1 | baseplate J/gp47 family protein | - |
| XFASM23_RS01925 | 456911..457249 | - | 339 | WP_004090694.1 | GPW/gp25 family protein | - |
| XFASM23_RS01930 | 457447..457728 | + | 282 | WP_004090695.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
| XFASM23_RS01935 | 457739..458014 | + | 276 | WP_004085172.1 | HigA family addiction module antidote protein | - |
| XFASM23_RS01940 | 458102..458404 | + | 303 | WP_004090696.1 | type II toxin-antitoxin system MqsR family toxin | Toxin |
| XFASM23_RS01945 | 458407..458808 | + | 402 | WP_004090697.1 | type II toxin-antitoxin system MqsA family antitoxin | Antitoxin |
| XFASM23_RS01950 | 458877..459464 | - | 588 | WP_011097612.1 | phage baseplate assembly protein V | - |
| XFASM23_RS01955 | 459461..460003 | - | 543 | WP_011097613.1 | hypothetical protein | - |
| XFASM23_RS01960 | 459979..460500 | - | 522 | WP_011097614.1 | hypothetical protein | - |
| XFASM23_RS01965 | 460497..460820 | - | 324 | WP_011097935.1 | hypothetical protein | - |
| XFASM23_RS01970 | 460820..461080 | - | 261 | WP_011097616.1 | hypothetical protein | - |
| XFASM23_RS01975 | 461098..462972 | - | 1875 | WP_011097617.1 | phage major capsid protein | - |
| XFASM23_RS01980 | 462969..463601 | - | 633 | WP_011097618.1 | phage portal protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 446054..468878 | 22824 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 101 a.a. Molecular weight: 10948.71 Da Isoelectric Point: 8.0251
>T22806 WP_004090696.1 NC_010577:458102-458404 [Xylella fastidiosa M23]
MEKGTSHYKLPVVKALVKAGKVRATATAYQGARELGIKDLTGMCTVVLALTSADFYKSMTTYADHTVFQDVYHAKTASGD
EVYLKLTVIDDVLIVSFKEL
MEKGTSHYKLPVVKALVKAGKVRATATAYQGARELGIKDLTGMCTVVLALTSADFYKSMTTYADHTVFQDVYHAKTASGD
EVYLKLTVIDDVLIVSFKEL
Download Length: 303 bp
>T22806 NC_010577:458102-458404 [Xylella fastidiosa M23]
ATGGAGAAAGGCACATCTCACTATAAGCTACCAGTCGTCAAAGCCTTGGTGAAAGCTGGCAAGGTCAGGGCTACAGCGAC
CGCCTACCAAGGAGCACGTGAGCTCGGCATCAAAGATTTAACTGGAATGTGCACCGTTGTCTTGGCGCTCACGTCTGCCG
ACTTCTACAAGAGCATGACGACCTACGCGGATCACACAGTATTCCAGGATGTGTACCACGCCAAGACGGCAAGCGGTGAT
GAGGTGTACCTGAAGTTAACTGTCATTGATGACGTGTTGATTGTTTCCTTCAAGGAGTTATGA
ATGGAGAAAGGCACATCTCACTATAAGCTACCAGTCGTCAAAGCCTTGGTGAAAGCTGGCAAGGTCAGGGCTACAGCGAC
CGCCTACCAAGGAGCACGTGAGCTCGGCATCAAAGATTTAACTGGAATGTGCACCGTTGTCTTGGCGCTCACGTCTGCCG
ACTTCTACAAGAGCATGACGACCTACGCGGATCACACAGTATTCCAGGATGTGTACCACGCCAAGACGGCAAGCGGTGAT
GAGGTGTACCTGAAGTTAACTGTCATTGATGACGTGTTGATTGTTTCCTTCAAGGAGTTATGA
Antitoxin
Download Length: 134 a.a. Molecular weight: 14944.02 Da Isoelectric Point: 7.1650
>AT22806 WP_004090697.1 NC_010577:458407-458808 [Xylella fastidiosa M23]
MRCPCCGAAELIHDTRDMLYTYKSETTSIPTVTGDFCPACGEVVLDREHGDRYSELVGLFQRQVNSAYVDPGYITKVRRK
LDLDQRQAAELFGGGVNAFSRYENGKTKPPLSLVKLFKLLDRHPDLLNEVKSS
MRCPCCGAAELIHDTRDMLYTYKSETTSIPTVTGDFCPACGEVVLDREHGDRYSELVGLFQRQVNSAYVDPGYITKVRRK
LDLDQRQAAELFGGGVNAFSRYENGKTKPPLSLVKLFKLLDRHPDLLNEVKSS
Download Length: 402 bp
>AT22806 NC_010577:458407-458808 [Xylella fastidiosa M23]
ATGAGATGTCCATGCTGCGGCGCGGCAGAACTGATCCACGACACGCGCGACATGCTTTACACCTACAAGAGCGAAACTAC
TAGTATCCCAACGGTGACCGGCGACTTCTGCCCGGCTTGTGGCGAAGTCGTCTTGGACCGTGAACATGGTGATCGTTACA
GCGAATTGGTCGGCTTGTTCCAACGTCAGGTGAATTCGGCCTACGTCGATCCTGGTTACATTACCAAGGTACGCCGGAAG
CTTGATCTCGACCAGCGGCAAGCTGCCGAACTGTTCGGTGGTGGTGTTAATGCTTTCTCACGTTACGAGAACGGTAAAAC
CAAGCCGCCGCTGTCTTTGGTTAAGTTATTCAAGCTTCTGGATCGCCACCCCGATTTGCTCAACGAAGTGAAGAGTTCCT
AA
ATGAGATGTCCATGCTGCGGCGCGGCAGAACTGATCCACGACACGCGCGACATGCTTTACACCTACAAGAGCGAAACTAC
TAGTATCCCAACGGTGACCGGCGACTTCTGCCCGGCTTGTGGCGAAGTCGTCTTGGACCGTGAACATGGTGATCGTTACA
GCGAATTGGTCGGCTTGTTCCAACGTCAGGTGAATTCGGCCTACGTCGATCCTGGTTACATTACCAAGGTACGCCGGAAG
CTTGATCTCGACCAGCGGCAAGCTGCCGAACTGTTCGGTGGTGGTGTTAATGCTTTCTCACGTTACGAGAACGGTAAAAC
CAAGCCGCCGCTGTCTTTGGTTAAGTTATTCAAGCTTCTGGATCGCCACCCCGATTTGCTCAACGAAGTGAAGAGTTCCT
AA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|