Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-RelB
Location 4560827..4561359 Replicon chromosome
Accession NZ_CP089309
Organism Thiocapsa bogorovii strain BBS

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag LT988_RS20235 Protein ID WP_232407304.1
Coordinates 4560827..4561090 (-) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag LT988_RS20240 Protein ID WP_232407305.1
Coordinates 4561093..4561359 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LT988_RS20210 (LT988_20210) 4556088..4557233 + 1146 WP_232407299.1 AAA family ATPase -
LT988_RS20215 (LT988_20215) 4557250..4558128 + 879 WP_232407300.1 hypothetical protein -
LT988_RS20220 (LT988_20220) 4558510..4559448 + 939 WP_232407301.1 Fic family protein -
LT988_RS20225 (LT988_20225) 4559730..4560146 + 417 WP_232407302.1 OsmC family protein -
LT988_RS20230 (LT988_20230) 4560200..4560766 - 567 WP_232407303.1 hypothetical protein -
LT988_RS20235 (LT988_20235) 4560827..4561090 - 264 WP_232407304.1 Txe/YoeB family addiction module toxin Toxin
LT988_RS20240 (LT988_20240) 4561093..4561359 - 267 WP_232407305.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LT988_RS20245 (LT988_20245) 4561631..4564822 - 3192 WP_232407306.1 multidrug efflux RND transporter permease subunit -
LT988_RS20250 (LT988_20250) 4564825..4566183 - 1359 WP_232407307.1 efflux RND transporter periplasmic adaptor subunit -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10351.75 Da        Isoelectric Point: 9.8554

>T228011 WP_232407304.1 NZ_CP089309:c4561090-4560827 [Thiocapsa bogorovii]
VRRIRFVPDAWDAYLYWQQQDRRTLKRINTLITDAAREPFAGIGKPEPLRGNLSGYWSRRIDDTHRLVYRATDTELVIIA
CRFHYDG

Download         Length: 264 bp

>T228011 NZ_CP123255:1044231-1044566 [Escherichia coli]
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCCGG
ACATCGTCCGGCTGTTGTCCTGAGTCCGTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTGTACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACGGTTGCCCCAGAGGAATTACAGCTCATTAAAGCCAAAATTAA
CGTGCTGATTGGGTAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9560.66 Da        Isoelectric Point: 4.7454

>AT228011 WP_232407305.1 NZ_CP089309:c4561359-4561093 [Thiocapsa bogorovii]
MKVVTYSHARNALKSVLDDVVRDADVTIISRRDAEGDAVVMSLDHYNNLVETLHLLSTPANAEALARAIRQDQAGEAQPR
TLFDADGG

Download         Length: 267 bp

>AT228011 NZ_CP123255:1043983-1044231 [Escherichia coli]
ATGATCCACAGTAGCGTAAAGCGTTGGGGAAATTCACCGGCGGTGCGGATCCCGGCTACGTTAATGCAGGCGCTCAATCT
GAATATTGATGATGAAGTGAAGATTGACCTGGTGGATGGCAAATTAATTATTGAGCCAGTGCGTAAAGAGCCCGTATTTA
CGCTTGCTGAACTGGTCAACGACATCACGCCGGAAAACCTCCACGAGAATATCGACTGGGGAGAGCCGAAAGATAAGGAA
GTCTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References