Detailed information of TA system
Overview
TA module
| Type | I | Classification (family/domain) | sprG-sprF/- |
| Location | 1119365..1119627 | Replicon | chromosome |
| Accession | NZ_CP089165 | ||
| Organism | Staphylococcus aureus strain UNC_SaCF07 | ||
Toxin (Protein)
| Gene name | SprG3 | Uniprot ID | Q2FWA7 |
| Locus tag | LTK18_RS05485 | Protein ID | WP_001802298.1 |
| Coordinates | 1119365..1119469 (+) | Length | 35 a.a. |
Antitoxin (RNA)
| Gene name | SprF2 | ||
| Locus tag | - | ||
| Coordinates | 1119464..1119627 (-) |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LTK18_RS05465 (LTK18_05465) | 1116162..1116944 | + | 783 | WP_000908182.1 | ABC transporter ATP-binding protein | - |
| LTK18_RS05470 (LTK18_05470) | 1117012..1117869 | + | 858 | WP_000370925.1 | Cof-type HAD-IIB family hydrolase | - |
| LTK18_RS05475 (LTK18_05475) | 1118527..1118685 | - | 159 | WP_001792784.1 | hypothetical protein | - |
| LTK18_RS05480 (LTK18_05480) | 1118678..1118848 | - | 171 | WP_001792292.1 | transposase | - |
| LTK18_RS05485 (LTK18_05485) | 1119365..1119469 | + | 105 | WP_001802298.1 | hypothetical protein | Toxin |
| - | 1119464..1119627 | - | 164 | - | - | Antitoxin |
| LTK18_RS05495 (LTK18_05495) | 1119902..1120993 | - | 1092 | WP_000495669.1 | hypothetical protein | - |
| LTK18_RS05500 (LTK18_05500) | 1121259..1122236 | - | 978 | WP_000019734.1 | CDF family zinc efflux transporter CzrB | - |
| LTK18_RS05505 (LTK18_05505) | 1122238..1122558 | - | 321 | WP_000003759.1 | Zn(II)-responsive metalloregulatory transcriptional repressor CzrA | - |
| LTK18_RS05510 (LTK18_05510) | 1122710..1123375 | + | 666 | WP_216777771.1 | SDR family oxidoreductase | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 35 a.a. Molecular weight: 3906.77 Da Isoelectric Point: 5.5724
>T227792 WP_001802298.1 NZ_CP089165:1119365-1119469 [Staphylococcus aureus]
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
Download Length: 105 bp
>T227792 NZ_CP123040:4104438-4104656 [Klebsiella pneumoniae]
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATCCCGACCTCTGTCTGGAAATTTATCCGCTAA
ATGTCTGATAAGCCATTAACTAAAACAGACTATTTGATGCGCTTACGTCGTTGCCAGACAATTGACACGCTGGAGCGCGT
CATTGAAAAAAATAAATATGAACTGTCTGATAATGAGCTGGCGGTATTTTACTCAGCTGCCGACCATCGTCTGGCGGAAC
TGACCATGAATAAGCTATACGATAAAATCCCGACCTCTGTCTGGAAATTTATCCGCTAA
Antitoxin
Download Length: 164 bp
>AT227792 NZ_CP089165:c1119627-1119464 [Staphylococcus aureus]
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT
GTAGTAAGTAGAAGCAAAAGATGAAAATCTTTAACTCTTGAAACACAAAAAGGGCAACACTCGGAAACATGTTACCCTAA
TGAGCCCGTTAAAAAGACGGTGACCTTATATTTTATTTAAAAATAGCCTTCAAAATGCCGGTCAAAGCGAATAGAAGGTT
ATTT
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
