Detailed information of TA system TA227743

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): sprA1-sprA1AS/-
• Location: 293679..293861
• Replicon: chromosome
• Accession: NZ_CP089159
• Organism: Staphylococcus aureus strain UNC_SaCF18

Toxin (Protein)

• Gene name: sprA1
• Uniprot ID: -
• Locus tag: LTK20_RS01890
• Protein ID: WP_001801861.1
• Coordinates: 293766..293861 (-)
• Length: 32 a.a.

Antitoxin (RNA)

Gene name	sprA1AS
Locus tag	-
Coordinates	293679..293738 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LTK20_RS01875	292817..293194	+	378	WP_001037045.1	DUF1433 domain-containing protein	-
LTK20_RS01880	293388..293564	+	177	Protein_333	transposase	-
LTK20_RS01885	293542..293643	-	102	WP_001791893.1	hypothetical protein	-
-	293679..293738	+	60	-	-	Antitoxin
LTK20_RS01890	293766..293861	-	96	WP_001801861.1	type I toxin-antitoxin system Fst family toxin PepA1	Toxin
LTK20_RS01895	294064..294207	+	144	WP_001549059.1	transposase	-
LTK20_RS01900	294811..295194	+	384	WP_000070811.1	hypothetical protein	-
LTK20_RS01905	295205..295381	+	177	WP_000375476.1	hypothetical protein	-
LTK20_RS01910	295383..295568	+	186	WP_000809857.1	hypothetical protein	-
LTK20_RS01915	295682..296323	+	642	WP_000494956.1	ImmA/IrrE family metallo-endopeptidase	-
LTK20_RS01920	296541..297092	-	552	WP_000414205.1	hypothetical protein	-
LTK20_RS01925	297190..297534	-	345	WP_000627551.1	DUF3969 family protein	-
LTK20_RS01930	297575..298201	-	627	Protein_343	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	275159..331301	56142

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 32 a.a.
• Molecular weight: 3554.32 Da
• Isoelectric Point: 10.4449

>T227743 WP_001801861.1 NZ_CP089159:c293861-293766 [Staphylococcus aureus]
VMLIFVHIIAPVISGCAIAFFSYWLSRRNTK

Nucleotide

• Length: 96 bp

>T227743 NZ_CP123029:877214-877621 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCACTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGTATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCACCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGATGGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCCGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA

Antitoxin

Nucleotide

• Length: 60 bp

>AT227743 NZ_CP089159:293679-293738 [Staphylococcus aureus]
ACAACGAAAATAAGTATTTACTTATACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Structures

Antitoxin