Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprG3-sprA1AS/-
Location 858204..858401 Replicon chromosome
Accession NZ_CP089157
Organism Staphylococcus aureus strain UNC_SaCF30

Toxin (Protein)


Gene name SprG3 Uniprot ID -
Locus tag LTK17_RS04285 Protein ID WP_073392962.1
Coordinates 858297..858401 (-) Length 35 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 858204..858242 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LTK17_RS04260 (LTK17_04260) 853278..853598 + 321 WP_000003759.1 Zn(II)-responsive metalloregulatory transcriptional repressor CzrA -
LTK17_RS04265 (LTK17_04265) 853600..854580 + 981 WP_000019741.1 CDF family zinc efflux transporter CzrB -
LTK17_RS04270 (LTK17_04270) 854846..855937 + 1092 WP_000495684.1 hypothetical protein -
LTK17_RS04275 (LTK17_04275) 856225..857871 + 1647 WP_000277709.1 IS1182-like element ISSau3 family transposase -
LTK17_RS04280 (LTK17_04280) 858184..858258 + 75 Protein_810 hypothetical protein -
- 858204..858242 + 39 - - Antitoxin
LTK17_RS04285 (LTK17_04285) 858297..858401 - 105 WP_073392962.1 hypothetical protein Toxin
LTK17_RS04290 (LTK17_04290) 859081..859239 + 159 WP_001792784.1 hypothetical protein -
LTK17_RS04295 (LTK17_04295) 859898..860755 - 858 WP_000370937.1 HAD family hydrolase -
LTK17_RS04300 (LTK17_04300) 860823..861605 - 783 WP_000908186.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 856225..857871 1646


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 35 a.a.        Molecular weight: 3920.80 Da        Isoelectric Point: 5.5724

>T227734 WP_073392962.1 NZ_CP089157:c858401-858297 [Staphylococcus aureus]
MLLLERTSMSDFEMLMIVLTIIGLVLISTQDHKK

Download         Length: 105 bp

>T227734 NZ_CP123024:c4327464-4327291 [Escherichia coli]
ATGGCACTATTCTCTAAAATATTAATTTTTTATGTGATTGGTGTGAACATATCCTTTGTCATTATCTGGTTTATCTCACA
TGAGAAAACACATATTCGTTTACTTAGTGCATTCCTGGTCGGAATAACCTGGCCAATGAGTCTGCCTGTGGCATTACTTT
TTTCTCTCTTTTAG

Antitoxin


Download         Length: 39 bp

>AT227734 NZ_CP089157:858204-858242 [Staphylococcus aureus]
AACATGTTACCCTAATGAGCCCGTTAAAAAGACGGTGAC

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References