Detailed information of TA system TA227699

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): yonT-as-bsrE/-
• Location: 2187735..2187952
• Replicon: chromosome
• Accession: NZ_CP089148
• Organism: Bacillus subtilis strain NIB353

Toxin (Protein)

• Gene name: yonT
• Uniprot ID: -
• Locus tag: LRO88_RS11860
• Protein ID: WP_019712271.1
• Coordinates: 2187735..2187911 (-)
• Length: 59 a.a.

Antitoxin (RNA)

Gene name	as-bsrE
Locus tag	-
Coordinates	2187852..2187952 (+)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
LRO88_RS11805 (2182827)	2182827..2183051	-	225	WP_231833899.1	hypothetical protein	-
LRO88_RS11810 (2183129)	2183129..2183293	-	165	WP_159376880.1	hypothetical protein	-
LRO88_RS11815 (2183330)	2183330..2183689	-	360	WP_159376881.1	hypothetical protein	-
LRO88_RS11820 (2183736)	2183736..2183990	-	255	WP_159376882.1	hypothetical protein	-
LRO88_RS11825 (2184033)	2184033..2184254	-	222	WP_159376883.1	hypothetical protein	-
LRO88_RS11830 (2184251)	2184251..2184703	-	453	WP_159376884.1	hypothetical protein	-
LRO88_RS11835 (2185033)	2185033..2186250	-	1218	WP_061891096.1	hypothetical protein	-
LRO88_RS11840 (2186269)	2186269..2186736	-	468	WP_231833900.1	hypothetical protein	-
LRO88_RS11845 (2186726)	2186726..2187115	-	390	WP_231833901.1	GIY-YIG nuclease family protein	-
LRO88_RS11850 (2187232)	2187232..2187420	-	189	WP_003230987.1	hypothetical protein	-
LRO88_RS11855 (2187465)	2187465..2187716	-	252	WP_159376885.1	hypothetical protein	-
LRO88_RS11860 (2187735)	2187735..2187911	-	177	WP_019712271.1	hypothetical protein	Toxin
- (2187852)	2187852..2187952	+	101	NuclAT_0	-	Antitoxin
- (2187852)	2187852..2187952	+	101	NuclAT_0	-	Antitoxin
- (2187852)	2187852..2187952	+	101	NuclAT_0	-	Antitoxin
- (2187852)	2187852..2187952	+	101	NuclAT_0	-	Antitoxin
LRO88_RS11865 (2188872)	2188872..2189066	+	195	WP_004399291.1	hypothetical protein	-
LRO88_RS11870 (2189106)	2189106..2190980	+	1875	Protein_2290	DNA-directed RNA polymerase YonO	-
LRO88_RS11875 (2191165)	2191165..2192067	+	903	WP_231833902.1	NUMOD3 domain-containing DNA-binding protein	-
LRO88_RS11880 (2192288)	2192288..2192920	+	633	WP_061891291.1	hypothetical protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	2118105..2249193	131088

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

No domain identified.

Sequences

Toxin

Protein

• Length: 59 a.a.
• Molecular weight: 6864.42 Da
• Isoelectric Point: 12.8833

>T227699 WP_019712271.1 NZ_CP089148:c2187911-2187735 [Bacillus subtilis]
VLEKVGIIVAFLISLTVLTINSLTIVEKVRNLKNGTSKKKKRIRKRLRPKRQRQRIRR

Nucleotide

• Length: 177 bp

>T227699 NZ_CP123017:1349959-1350357 [Escherichia coli]
ATGCTGAAATTCATGCTGGATACCAATATCTGTATTTTCACTATTAAGAATAAACCAGTACATGTCAGAGAGCGGTTTAA
CCTGAATTCTGGCCGGATGTGTATAAGTTCTGTAACATTGATGGAGCTTATCTATGGGGCAGAAAAAAGTCAGATGCCAG
AACGCAATTTGGCGGTTATTGAAGGTTTCGTATCTCGTTTGGTAGTGCTTGATTATGATAGTGCTGCTGCGACGCATACC
GGGCAAATCAGGGCCGAGCTTGCCCGGCAGGGAAGGCCTGTTGGACCTTTTGACCAGATGATAGCGGGACATGCTCGCAG
TCGCGGTTTGATTGTGGTTACCAACAATACCCGAGAGTTTGAGCGAGTGGCGGGAATCAGACTAGAAGACTGGAGCTAA

Antitoxin

Nucleotide

• Length: 101 bp

>AT227699 NZ_CP089148:2187852-2187952 [Bacillus subtilis]
GATTGTAAGAACCGTTAAAGATATGAGGAAAGCAACTATGATACCCACTTTCTCAAGCACTATGTACACCTCCTTTCCTA
TGACTCTATTATAACATAATT

Structures

Antitoxin