Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | mqsRA (relBE)/MqsR-MqsA |
Location | 118506..119206 | Replicon | plasmid unnamed |
Accession | NZ_CP088924 | ||
Organism | Rhodanobacter thiooxydans strain FW510-R12 |
Toxin (Protein)
Gene name | mqsR | Uniprot ID | - |
Locus tag | LRK53_RS18660 | Protein ID | WP_235642675.1 |
Coordinates | 118910..119206 (-) | Length | 99 a.a. |
Antitoxin (Protein)
Gene name | mqsA | Uniprot ID | - |
Locus tag | LRK53_RS18655 | Protein ID | WP_235642674.1 |
Coordinates | 118506..118907 (-) | Length | 134 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LRK53_RS18645 (LRK53_18645) | 116282..117406 | + | 1125 | WP_235642672.1 | RHS repeat-associated core domain-containing protein | - |
LRK53_RS18650 (LRK53_18650) | 118144..118494 | + | 351 | WP_235642673.1 | transposase | - |
LRK53_RS18655 (LRK53_18655) | 118506..118907 | - | 402 | WP_235642674.1 | type II toxin-antitoxin system MqsA family antitoxin | Antitoxin |
LRK53_RS18660 (LRK53_18660) | 118910..119206 | - | 297 | WP_235642675.1 | type II toxin-antitoxin system MqsR family toxin | Toxin |
LRK53_RS18665 (LRK53_18665) | 119475..120146 | + | 672 | WP_235642676.1 | S24 family peptidase | - |
LRK53_RS18670 (LRK53_18670) | 120156..120818 | + | 663 | WP_235642677.1 | translesion DNA synthesis-associated protein ImuA | - |
LRK53_RS18675 (LRK53_18675) | 120778..122163 | + | 1386 | WP_235642678.1 | DNA polymerase Y family protein | - |
LRK53_RS18680 (LRK53_18680) | 122180..122911 | - | 732 | WP_235642679.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | inside | Non-Mobilizable plasmid | - | - | 1..218064 | 218064 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 99 a.a. Molecular weight: 10762.40 Da Isoelectric Point: 7.2755
>T227148 WP_235642675.1 NZ_CP088924:c119206-118910 [Rhodanobacter thiooxydans]
MEKRTPHCQLAVVKTLIADGKVRSTFSALTGGAALGFDFDGIVSVVASLTPKDFYKSMTTHADHRVWQDVYRPSTSAGEV
YLKLTVIDDVLIVSFKEL
MEKRTPHCQLAVVKTLIADGKVRSTFSALTGGAALGFDFDGIVSVVASLTPKDFYKSMTTHADHRVWQDVYRPSTSAGEV
YLKLTVIDDVLIVSFKEL
Download Length: 297 bp
>T227148 NZ_CP122727:873731-874138 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCACTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGTATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCACCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGATGGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCTGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCACTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGTATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCACCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGATGGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCTGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA
Antitoxin
Download Length: 134 a.a. Molecular weight: 14472.76 Da Isoelectric Point: 6.9045
>AT227148 WP_235642674.1 NZ_CP088924:c118907-118506 [Rhodanobacter thiooxydans]
MKCPSCAGAELVRDTRDLPYTYKGESTLIPSVTGDFCPICGEMILDVAESVRTSAVMLDFNKQVNASIVDPSFIASVRKK
LALDQREAAEIFGGGVNAFSRYETGKTKPPLALVKLLKVLDRHPDLLNEVRAA
MKCPSCAGAELVRDTRDLPYTYKGESTLIPSVTGDFCPICGEMILDVAESVRTSAVMLDFNKQVNASIVDPSFIASVRKK
LALDQREAAEIFGGGVNAFSRYETGKTKPPLALVKLLKVLDRHPDLLNEVRAA
Download Length: 402 bp
>AT227148 NZ_CP122727:873484-873750 [Escherichia coli]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|
Antitoxin
Source | ID | Structure |
---|