Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 118506..119206 Replicon plasmid unnamed
Accession NZ_CP088924
Organism Rhodanobacter thiooxydans strain FW510-R12

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag LRK53_RS18660 Protein ID WP_235642675.1
Coordinates 118910..119206 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag LRK53_RS18655 Protein ID WP_235642674.1
Coordinates 118506..118907 (-) Length 134 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LRK53_RS18645 (LRK53_18645) 116282..117406 + 1125 WP_235642672.1 RHS repeat-associated core domain-containing protein -
LRK53_RS18650 (LRK53_18650) 118144..118494 + 351 WP_235642673.1 transposase -
LRK53_RS18655 (LRK53_18655) 118506..118907 - 402 WP_235642674.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
LRK53_RS18660 (LRK53_18660) 118910..119206 - 297 WP_235642675.1 type II toxin-antitoxin system MqsR family toxin Toxin
LRK53_RS18665 (LRK53_18665) 119475..120146 + 672 WP_235642676.1 S24 family peptidase -
LRK53_RS18670 (LRK53_18670) 120156..120818 + 663 WP_235642677.1 translesion DNA synthesis-associated protein ImuA -
LRK53_RS18675 (LRK53_18675) 120778..122163 + 1386 WP_235642678.1 DNA polymerase Y family protein -
LRK53_RS18680 (LRK53_18680) 122180..122911 - 732 WP_235642679.1 hypothetical protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..218064 218064


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(5-97)

Antitoxin

(3-131)


Sequences


Toxin        


Download         Length: 99 a.a.        Molecular weight: 10762.40 Da        Isoelectric Point: 7.2755

>T227148 WP_235642675.1 NZ_CP088924:c119206-118910 [Rhodanobacter thiooxydans]
MEKRTPHCQLAVVKTLIADGKVRSTFSALTGGAALGFDFDGIVSVVASLTPKDFYKSMTTHADHRVWQDVYRPSTSAGEV
YLKLTVIDDVLIVSFKEL

Download         Length: 297 bp

>T227148 NZ_CP122727:873731-874138 [Escherichia coli]
GTGGTCCTGTGGCAATCTGATTTGCGCGTCTCCTGGCGCGCACAGTGGCTTTCCTTGCTGATTCATGGGCTGGTTGCCGC
TGTTATTTTACTCATGCCCTGGCCACTCAGTTACACCCCGTTATGGATGGTGTTACTTTCGCTGGTGGTGTTTGATTGCG
TTCGCAGCCAGCGGCGTATTAATGCTCGCCAGGGGGAAATTCGCTTGTTGATGGACGGGCGTTTGCGTTGGCAAGGGCAG
GAGTGGAGCATCGTCAAAGCACCGTGGATGATTAAGAGCGGCATGATGCTGCGTTTACGTTCTGATGGCGGTAAACGGCA
ACATTTATGGCTGGCAGCCGACAGCATGGACGAAGCTGAATGGCGGGATTTACGGCGGATTTTGTTGCAACAAGAGACGC
AAAGATAA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14472.76 Da        Isoelectric Point: 6.9045

>AT227148 WP_235642674.1 NZ_CP088924:c118907-118506 [Rhodanobacter thiooxydans]
MKCPSCAGAELVRDTRDLPYTYKGESTLIPSVTGDFCPICGEMILDVAESVRTSAVMLDFNKQVNASIVDPSFIASVRKK
LALDQREAAEIFGGGVNAFSRYETGKTKPPLALVKLLKVLDRHPDLLNEVRAA

Download         Length: 402 bp

>AT227148 NZ_CP122727:873484-873750 [Escherichia coli]
ATGGACATTAACAACAAAGCCCGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAACTCGATATTTCAATCATGCCGTT
TTTCGAACATGAGTACGACAGCTTAAGCGATGACGAAAAACGCATCTTTATTCGTCTGCTGGAATGTGACGATCCGGACC
TGTTTAACTGGCTGATGAATCACGGTAAACCGGCCGATGCAGAACTGGAAATGATGGTCCGACTCATCCAGACACGGAAC
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References