226960

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-sprA1AS/-
Location 1026505..1026666 Replicon chromosome
Accession NZ_CP088218
Organism Staphylococcus sp. HL28

Toxin (Protein)


Gene name SprA2 Uniprot ID -
Locus tag LPC11_RS05065 Protein ID WP_015364873.1
Coordinates 1026505..1026600 (+) Length 32 a.a.

Antitoxin (RNA)


Gene name sprA1AS
Locus tag -
Coordinates 1026632..1026666 (-)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPC11_RS05055 (LPC11_05055) 1022046..1024979 + 2934 WP_107566521.1 AAA family ATPase -
LPC11_RS05060 (LPC11_05060) 1024979..1025920 + 942 WP_023373048.1 3'-5' exoribonuclease YhaM -
LPC11_RS05065 (LPC11_05065) 1026505..1026600 + 96 WP_015364873.1 type I toxin-antitoxin system Fst family toxin Toxin
- 1026632..1026666 - 35 - - Antitoxin
LPC11_RS05070 (LPC11_05070) 1026752..1027744 - 993 WP_002466825.1 peptidylprolyl isomerase -
LPC11_RS05075 (LPC11_05075) 1027922..1028479 - 558 WP_023373046.1 DUF3267 domain-containing protein -
LPC11_RS05080 (LPC11_05080) 1028668..1029039 - 372 WP_002452114.1 YtxH domain-containing protein -
LPC11_RS05085 (LPC11_05085) 1029117..1029542 - 426 WP_023373044.1 HIT family protein -
LPC11_RS05090 (LPC11_05090) 1029674..1030414 + 741 WP_023373042.1 ABC transporter ATP-binding protein -
LPC11_RS05095 (LPC11_05095) 1030407..1031630 + 1224 WP_023373041.1 ABC transporter permease -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 32 a.a.        Molecular weight: 3610.26 Da        Isoelectric Point: 8.0878

>T226960 WP_015364873.1 NZ_CP088218:1026505-1026600 [Staphylococcus sp. HL28]
MTEIFVHIATTVISGCIVTLFAHWLRHRNDK

Download         Length: 96 bp

>T226960 NZ_CP122663:c22092-21838 [Escherichia coli]
ATGAGAAAAAACAAAGGGCGATTGACTTATTATCTTGAAGTGATTGATAAAAAATACCATTTTGTAAAAAAAATAAGCAG
TTATTCAAAGGAGTTCACTGACGGAAAAACAAAAAGAACAAAGAGAACGTTAAGTGAGCTGGTTTTTAATGAAAGTGAGG
TCGAGGCAATAGACTTTACAAAAAATGGTTTAAGACCTGTTGATAAGAATATTCTCTTAACTATGGTGAAAGAATATAAG
GAGAGTGATGCATGA

Antitoxin


Download         Length: 35 bp

>AT226960 NZ_CP088218:c1026666-1026632 [Staphylococcus sp. HL28]
ACACCAATCCCCTCACTATTTGCGGTAGTGAGGGG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Download structure file

References