Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type I Classification (family/domain) SprA2-SprA2AS/-
Location 2526382..2526566 Replicon chromosome
Accession NZ_CP088157
Organism Staphylococcus aureus strain 199

Toxin (Protein)


Gene name SprA2 Uniprot ID A0A2P7CQJ7
Locus tag LQK05_RS12815 Protein ID WP_000482647.1
Coordinates 2526459..2526566 (-) Length 36 a.a.

Antitoxin (RNA)


Gene name SprA2AS
Locus tag -
Coordinates 2526382..2526442 (+)

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQK05_RS12800 2521912..2522079 - 168 WP_001792506.1 hypothetical protein -
LQK05_RS12805 2522310..2524043 - 1734 WP_000486491.1 ABC transporter ATP-binding protein -
LQK05_RS12810 2524068..2525831 - 1764 WP_001064816.1 ABC transporter ATP-binding protein -
- 2526382..2526442 + 61 - - Antitoxin
LQK05_RS12815 2526459..2526566 - 108 WP_000482647.1 type I toxin-antitoxin system Fst family toxin Toxin
LQK05_RS12820 2526700..2527086 - 387 WP_000779347.1 flippase GtxA -
LQK05_RS12825 2527344..2528486 + 1143 WP_072519225.1 glycerate kinase -
LQK05_RS12830 2528546..2529205 + 660 WP_000831298.1 membrane protein -
LQK05_RS12835 2529387..2530598 + 1212 WP_001192075.1 multidrug effflux MFS transporter -
LQK05_RS12840 2530721..2531194 - 474 WP_000456489.1 GyrI-like domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.



Sequences

Toxin        


Download         Length: 36 a.a.        Molecular weight: 4012.76 Da        Isoelectric Point: 10.4935

>T226877 WP_000482647.1 NZ_CP088157:c2526566-2526459 [Staphylococcus aureus]
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK

Download         Length: 108 bp

>T226877 NZ_CP122648:2226986-2227089 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 61 bp

>AT226877 NZ_CP088157:2526382-2526442 [Staphylococcus aureus]
TACATAATAAATTGAACATCTAAATACACCAAATCCCCTCACTACTGCCATAGTGAGGGGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A2P7CQJ7

Antitoxin

Download structure file

References