226569

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-VapI
Location 5967173..5967783 Replicon chromosome
Accession NZ_CP088014
Organism Bradyrhizobium daqingense strain CCBAU 15774

Toxin (Protein)


Gene name graT Uniprot ID -
Locus tag LPJ38_RS28415 Protein ID WP_145629817.1
Coordinates 5967499..5967783 (-) Length 95 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag LPJ38_RS28410 Protein ID WP_145629818.1
Coordinates 5967173..5967490 (-) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LPJ38_RS28390 (LPJ38_28390) 5963390..5964418 - 1029 WP_158644734.1 acyltransferase -
LPJ38_RS28395 (LPJ38_28395) 5964774..5965568 - 795 WP_145629820.1 ATP12 family protein -
LPJ38_RS28400 (LPJ38_28400) 5965622..5965930 - 309 WP_231088426.1 hypothetical protein -
LPJ38_RS28405 (LPJ38_28405) 5965962..5967176 - 1215 WP_145629819.1 RluA family pseudouridine synthase -
LPJ38_RS28410 (LPJ38_28410) 5967173..5967490 - 318 WP_145629818.1 HigA family addiction module antitoxin Antitoxin
LPJ38_RS28415 (LPJ38_28415) 5967499..5967783 - 285 WP_145629817.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LPJ38_RS28420 (LPJ38_28420) 5967840..5969174 - 1335 WP_145629816.1 replication-associated recombination protein A -
LPJ38_RS28425 (LPJ38_28425) 5969171..5970577 - 1407 WP_167520291.1 DegQ family serine endoprotease -
LPJ38_RS28430 (LPJ38_28430) 5970889..5972502 + 1614 WP_145629815.1 OprO/OprP family phosphate-selective porin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(1-94)

Antitoxin

Cro/C1-type helix-turn-helix domain

(9-66)


Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10594.89 Da        Isoelectric Point: 6.4615

>T226569 WP_145629817.1 NZ_CP088014:c5967783-5967499 [Bradyrhizobium daqingense]
MILGYRDKRTERFAAGQHVKEFSGFARQAETRLDRLDAATSLADLAALPGNRLEALKGDRAGQFSIRINDQWRICFSWPE
GSLGPTDVEIVDYH

Download         Length: 285 bp

>T226569 NZ_CP122517:2682665-2682772 [Escherichia coli]
ATGACGCTCGCGAAGTTTGCCATGATTTTCTGGCACGACCTGGCAGCACCGATCCTGGCGGGGATTATTACCGCAGCGAT
TGTCGGCTGGTGGCGTAACCGGAAGTAA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 11686.34 Da        Isoelectric Point: 10.5812

>AT226569 WP_145629818.1 NZ_CP088014:c5967490-5967173 [Bradyrhizobium daqingense]
MPRTPIHPGEQLAEELRELGITAAELARQIDVPVNRVTGIINGQRGITADTALRLGHWFGTSPQFWMNLQQQYELRLAEK
EIGAQVASLPRRANTQSTRKLGKTA

Download         Length: 318 bp

>AT226569 NZ_CP122517:c2682612-2682551 [Escherichia coli]
TGGTTCAAGATTAGCCCCCGTTCTGTTGTCAGGTTTTACCTCTCAACGTGCGGGGGTTTTCT

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References