Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 765636..766306 Replicon chromosome
Accession NZ_CP088000
Organism Stenotrophomonas rhizophila strain Bl2-2

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag LQE85_RS03540 Protein ID WP_095364488.1
Coordinates 765965..766306 (-) Length 114 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag LQE85_RS03535 Protein ID WP_093536208.1
Coordinates 765636..765965 (-) Length 110 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LQE85_RS03510 (LQE85_03510) 761446..761913 + 468 WP_093536119.1 RcnB family protein -
LQE85_RS03515 (LQE85_03515) 762033..763286 + 1254 WP_249833757.1 serine hydroxymethyltransferase -
LQE85_RS03520 (LQE85_03520) 763286..763729 + 444 WP_210132022.1 hypothetical protein -
LQE85_RS03525 (LQE85_03525) 763823..764344 + 522 WP_068849191.1 transcriptional regulator NrdR -
LQE85_RS03530 (LQE85_03530) 764462..765544 + 1083 WP_249833758.1 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD -
LQE85_RS03535 765636..765965 - 330 WP_093536208.1 transcriptional regulator Antitoxin
LQE85_RS03540 (LQE85_03540) 765965..766306 - 342 WP_095364488.1 toxin Toxin
LQE85_RS03545 (LQE85_03545) 766517..767149 - 633 WP_095364489.1 hypothetical protein -
LQE85_RS03550 (LQE85_03550) 767526..768137 + 612 WP_249833759.1 riboflavin synthase -
LQE85_RS03555 (LQE85_03555) 768134..769249 + 1116 WP_068849203.1 3,4-dihydroxy-2-butanone-4-phosphate synthase -
LQE85_RS03560 (LQE85_03560) 769433..769900 + 468 WP_068854542.1 6,7-dimethyl-8-ribityllumazine synthase -
LQE85_RS03565 (LQE85_03565) 769897..770376 + 480 WP_068849204.1 transcription antitermination factor NusB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(44-93)


Sequences

Toxin        


Download         Length: 114 a.a.        Molecular weight: 12909.03 Da        Isoelectric Point: 10.7436

>T226548 WP_095364488.1 NZ_CP088000:c766306-765965 [Stenotrophomonas rhizophila]
MHAVFVEMPAFSRHRAAYLDNDGLCALQQFLLRAPEAGDVIVGTGGLRKLRFSDDRRQRGKRGGLRVIYFHWPAGSQFWL
FTLYGKGVQDDLDAMQKRLLKRMLEAVLLARTT

Download         Length: 342 bp

>T226548 NZ_CP122510:7784-8164 [Escherichia coli]
ATGAGGCATATATCACCGGAAGAACTTATTGCGCTTCATGATGCGAATATAAGCCGCTACGGCGGCCTGCCGGGAATGTC
AGATCCGGGTAGGGCAGAGGCCATTATCGGGAGAGTTCAGGCCAGAGTTGCCTACGAAGAGATCACCGACCTTTTCGAAG
TCTCCGCCACCTACCTGGTGGCTACGGCGAGAGGGCATATATTCAATGATGCCAATAAGCGTACCGCGCTAAACAGTGCG
CTGCTATTTCTACGCCGTAACGGTATACAGGTATATGATTCTCCCGTGCTGGTGGAACTTGCGGTGGGGGCCGCAACTGG
TGAAATCCCCGTATCTTCAGTAGCGGAAAAACTACGTGAATTATTTGGTTCCAATATTTGA

Antitoxin


Download         Length: 110 a.a.        Molecular weight: 12445.33 Da        Isoelectric Point: 10.5713

>AT226548 WP_093536208.1 NZ_CP088000:c765965-765636 [Stenotrophomonas rhizophila]
MKRDVFAELVEGLHALEDERAGKTTLRTHKVRLQPLPPLHAGELVAIREQLNMSRPVFAMYLRTNARTLENWEQGRARPN
AQASTLIRLVQQFPQTVRHLEALQPDVAS

Download         Length: 330 bp

>AT226548 NZ_CP122510:7563-7784 [Escherichia coli]
ATGCAATCCATTAACTTCCGTACCGCGCGCGGCAACCTTTCTGAAGTGCTCAACAATGTTGAAGCCGGGGAAGAGGTTGA
AATCACCCGCAGAGGCCGAGAGCCAGCAGTAATTGTCAGCAAGGCTACTTTTGAAGCCTACAAAAAAGCGGCGCTGGATG
CTGAATTTGCATCCCTGTTTGACACCCTGGACTCCACCAACAAGGAACTGGTTAACCGATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References