Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/HTH(antitoxin) |
| Location | 338147..338761 | Replicon | chromosome |
| Accession | NZ_CP088000 | ||
| Organism | Stenotrophomonas rhizophila strain Bl2-2 | ||
Toxin (Protein)
| Gene name | higB | Uniprot ID | - |
| Locus tag | LQE85_RS01500 | Protein ID | WP_249833544.1 |
| Coordinates | 338447..338761 (-) | Length | 105 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | A0A1B2N027 |
| Locus tag | LQE85_RS01495 | Protein ID | WP_068848524.1 |
| Coordinates | 338147..338443 (-) | Length | 99 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LQE85_RS01465 (LQE85_01465) | 333509..334399 | + | 891 | WP_068848514.1 | 3-hydroxyisobutyrate dehydrogenase | - |
| LQE85_RS01470 (LQE85_01470) | 334567..334992 | - | 426 | WP_093535056.1 | organic hydroperoxide resistance protein | - |
| LQE85_RS01475 (LQE85_01475) | 335104..335934 | + | 831 | WP_249833541.1 | AraC family transcriptional regulator | - |
| LQE85_RS01480 (LQE85_01480) | 335927..336385 | - | 459 | WP_249833542.1 | hypothetical protein | - |
| LQE85_RS01485 (LQE85_01485) | 336572..337528 | - | 957 | WP_249833543.1 | cation transporter | - |
| LQE85_RS01490 (LQE85_01490) | 337638..338114 | + | 477 | WP_095362572.1 | hypothetical protein | - |
| LQE85_RS01495 (LQE85_01495) | 338147..338443 | - | 297 | WP_068848524.1 | helix-turn-helix domain-containing protein | Antitoxin |
| LQE85_RS01500 (LQE85_01500) | 338447..338761 | - | 315 | WP_249833544.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LQE85_RS19705 | 339047..339172 | + | 126 | WP_257784590.1 | hypothetical protein | - |
| LQE85_RS01505 (LQE85_01505) | 339162..339560 | - | 399 | WP_068854502.1 | hypothetical protein | - |
| LQE85_RS01510 (LQE85_01510) | 339773..339937 | + | 165 | WP_249833545.1 | hypothetical protein | - |
| LQE85_RS01515 (LQE85_01515) | 339995..340090 | - | 96 | Protein_302 | DUF3011 domain-containing protein | - |
| LQE85_RS01520 (LQE85_01520) | 340211..340450 | - | 240 | WP_068848528.1 | hypothetical protein | - |
| LQE85_RS01525 (LQE85_01525) | 340716..341501 | - | 786 | WP_249833546.1 | hypothetical protein | - |
| LQE85_RS01530 (LQE85_01530) | 341494..341724 | - | 231 | WP_068848532.1 | hypothetical protein | - |
| LQE85_RS01535 (LQE85_01535) | 341721..341897 | - | 177 | WP_167693286.1 | hypothetical protein | - |
| LQE85_RS01540 (LQE85_01540) | 341890..342162 | - | 273 | WP_249833547.1 | hypothetical protein | - |
| LQE85_RS01545 (LQE85_01545) | 342155..342580 | - | 426 | WP_068848536.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 105 a.a. Molecular weight: 11604.62 Da Isoelectric Point: 10.2334
>T226547 WP_249833544.1 NZ_CP088000:c338761-338447 [Stenotrophomonas rhizophila]
MLFIETPTFTRAIKGLMPDDDYARFQLELAASPLVGDVIEGTGGLRKVRLGIPGRGKRGGARVIYYYIAPSSRIILLLVY
PRNVQDALTAEQKIALRSIIENWK
MLFIETPTFTRAIKGLMPDDDYARFQLELAASPLVGDVIEGTGGLRKVRLGIPGRGKRGGARVIYYYIAPSSRIILLLVY
PRNVQDALTAEQKIALRSIIENWK
Download Length: 315 bp
>T226547 NZ_CP122509:44109-44414 [Escherichia coli]
ATGCAGTTTAAGGTTTACACCTATAAAAGAGAGAGCCGTTATCGTCTGTTTGTGGATGTACAGAGTGATATTATTGACAC
GCCCGGGCGACGGATGGTGATCCCCCTGGCCAGTGCACGTCTGCTGTCAGATAAAGTCTCCCGTGAACTTTACCCGGTGG
TGCATATCGGGGATGAAAGCTGGCGCATGATGACCACCGATATGGCCAGTGTGCCGGTCTCCGTTATCGGGGAAGAAGTG
GCTGATCTCAGCCACCGCGAAAATGACATCAAAAACGCCATTAACCTGATGTTCTGGGGAATATAA
ATGCAGTTTAAGGTTTACACCTATAAAAGAGAGAGCCGTTATCGTCTGTTTGTGGATGTACAGAGTGATATTATTGACAC
GCCCGGGCGACGGATGGTGATCCCCCTGGCCAGTGCACGTCTGCTGTCAGATAAAGTCTCCCGTGAACTTTACCCGGTGG
TGCATATCGGGGATGAAAGCTGGCGCATGATGACCACCGATATGGCCAGTGTGCCGGTCTCCGTTATCGGGGAAGAAGTG
GCTGATCTCAGCCACCGCGAAAATGACATCAAAAACGCCATTAACCTGATGTTCTGGGGAATATAA
Antitoxin
Download Length: 99 a.a. Molecular weight: 10936.58 Da Isoelectric Point: 10.2880
>AT226547 WP_068848524.1 NZ_CP088000:c338443-338147 [Stenotrophomonas rhizophila]
MDNTLFAELMGSVAEADEILKGNQVPSRELHVSPVQVREIRRATGLSQQKFARIIHVDVGTLRNWEQGRRDPTGPARALL
HVIMKNPKETLRVLAEAG
MDNTLFAELMGSVAEADEILKGNQVPSRELHVSPVQVREIRRATGLSQQKFARIIHVDVGTLRNWEQGRRDPTGPARALL
HVIMKNPKETLRVLAEAG
Download Length: 297 bp
>AT226547 NZ_CP122509:43889-44107 [Escherichia coli]
ATGAAGCAGCGTATTACAGTGACAGTTGACAGCGACAGCTATCAGTTGCTCAAGGCATATGATGTCAATATCTCCGGTCT
GGTAAGCACAACCATGCAGAATGAAGCCCGTCGTCTGCGTGCCGAACGCTGGAAAGCGGAAAATCAGGAAGGGATGGCTG
AGGTCGCCCGGTTTATTGAAATGAACGGCTCTTTTGCTGACGAGAACAGGGACTGGTGA
ATGAAGCAGCGTATTACAGTGACAGTTGACAGCGACAGCTATCAGTTGCTCAAGGCATATGATGTCAATATCTCCGGTCT
GGTAAGCACAACCATGCAGAATGAAGCCCGTCGTCTGCGTGCCGAACGCTGGAAAGCGGAAAATCAGGAAGGGATGGCTG
AGGTCGCCCGGTTTATTGAAATGAACGGCTCTTTTGCTGACGAGAACAGGGACTGGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|