Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 4480524..4481332 Replicon chromosome
Accession NZ_CP087880
Organism Pseudocitrobacter corydidari isolate G163CM

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag G163CM_RS20935 Protein ID WP_231826148.1
Coordinates 4480524..4480997 (-) Length 158 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag G163CM_RS20940 Protein ID WP_231826149.1
Coordinates 4480997..4481332 (-) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
G163CM_RS20915 (4476546) 4476546..4477460 - 915 WP_231826145.1 1-phosphofructokinase -
G163CM_RS20920 (4477471) 4477471..4478325 - 855 WP_000469985.1 tagatose bisphosphate family class II aldolase -
G163CM_RS20925 (4478660) 4478660..4479493 + 834 WP_231826146.1 DeoR/GlpR family DNA-binding transcription regulator -
G163CM_RS20930 (4479504) 4479504..4480451 + 948 WP_231826147.1 sugar kinase -
G163CM_RS20935 (4480524) 4480524..4480997 - 474 WP_231826148.1 type II toxin-antitoxin system YhaV family toxin Toxin
G163CM_RS20940 (4480997) 4480997..4481332 - 336 WP_231826149.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
G163CM_RS20945 (4481483) 4481483..4483054 - 1572 WP_231826150.1 galactarate dehydratase -
G163CM_RS20950 (4483470) 4483470..4484801 + 1332 WP_231826151.1 galactarate/glucarate/glycerate transporter GarP -
G163CM_RS20955 (4484830) 4484830..4485600 + 771 WP_015962895.1 2-dehydro-3-deoxyglucarate aldolase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(12-150)

Antitoxin

PrlF antitoxin

(14-110)


Sequences

Toxin        


Download         Length: 158 a.a.        Molecular weight: 18112.69 Da        Isoelectric Point: 9.8283

>T226467 WP_231826148.1 NZ_CP087880:c4480997-4480524 [Pseudocitrobacter corydidari]
MDFPHKVNGWALYAHPCFQETYDALVEDVEILKGKDPENYQKKAATRLLAVVHKVIEEHITVSPSSPSFRHGKTLGTGNH
KDWSRAKFGAGRYRLFFRYSEKERVIILGWMNDEHTLRSYGKKSDAYTTFCKMLKKGHPPADWESLLQEALTSAKRK

Download         Length: 474 bp

>T226467 NZ_CP122496:c2320350-2320174 [Escherichia coli]
GTGAAACAAAGCGAGTTCAGACGTTGGCTCGAATCTCAGGGCGTCGATGTAGCGAATGGCAGCAACCATTTGAAACTCAG
GTTTCATGGGAGGCGCAGTGTCATGCCGCGTCACCCCTGCGATGAGATTAAAGAACCATTGCGTAAAGCAATCCTGAAAC
AACTCGGTTTGAGTTAA

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12427.91 Da        Isoelectric Point: 4.2476

>AT226467 WP_231826149.1 NZ_CP087880:c4481332-4480997 [Pseudocitrobacter corydidari]
MLAYARSDAVLTTESKVTVRGQTTLPTPVREALKLKPGEDSIQYDILPGGQVLMSRVGDEQEDHTMKAFLQFLDTDIQNH
PQQLRPFDMHQGRTLVSGMDINIDDEIGDDD

Download         Length: 336 bp

>AT226467 NZ_CP122496:c2320128-2319712 [Escherichia coli]
ATGCGTTATCCCGTCACTCTTACACCCGCGCCGGAAGGCGGTTATATGGTTTCTTTTGTGGATATCCCTGAAGCGTTGAC
GCAGGGCGAAACTGTCGCTGAAGCGATGGAAGCGGCAAAAGATGCTTTACTGACCGCATTTGATTTTTATTTTGAAGATA
ACGAGCTTATCCCTTTACCTTCGCCATTAAATAGTCATGATCACTTTATTGAAGTACCTTTGAGCGTCGCCTCTAAGGTA
TTGCTGTTAAATGCTTTTTTACAGTCAGAAATCACTCAGCAAGAGTTAGCCAGGCGAATTGGCAAACCTAAACAGGAGAT
TACTCGCCTATTTAACTTGCATCATGCGACAAAAATCGACGCCGTCCAGCTCGCGGCAAAGGCGCTTGGCAAAGAGTTAT
CGCTGGTGATGGTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References