Detailed information of TA system TA226463

Bioinformatically predicted

Overview

TA module

• Type: I
• Classification (family/domain): hok-sok/-
• Location: 4070148..4070405
• Replicon: chromosome
• Accession: NZ_CP087880
• Organism: Pseudocitrobacter corydidari isolate G163CM

Toxin (Protein)

• Gene name: hokA
• Uniprot ID: -
• Locus tag: G163CM_RS18895
• Protein ID: WP_144052219.1
• Coordinates: 4070253..4070405 (+)
• Length: 51 a.a.

Antitoxin (RNA)

Gene name	sokA
Locus tag	-
Coordinates	4070148..4070202 (-)

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
G163CM_RS18870	4065420..4065725	+	306	WP_015962543.1	YsaB family lipoprotein	-
G163CM_RS18875	4065864..4066775	+	912	WP_231825954.1	glycine--tRNA ligase subunit alpha	-
G163CM_RS18880	4066785..4068854	+	2070	WP_231825955.1	glycine--tRNA ligase subunit beta	-
G163CM_RS18885	4069173..4069325	+	153	WP_144052218.1	type I toxin-antitoxin system toxin HokA	-
G163CM_RS18890	4069713..4069865	+	153	WP_231825956.1	type I toxin-antitoxin system toxin HokA	-
-	4070148..4070202	-	55	-	-	Antitoxin
G163CM_RS18895	4070253..4070405	+	153	WP_144052219.1	type I toxin-antitoxin system toxin HokA	Toxin
G163CM_RS18900	4070571..4070783	-	213	WP_000014594.1	RNA chaperone/antiterminator CspA	-
G163CM_RS18905	4071053..4071334	-	282	WP_231825957.1	HTH-type transcriptional regulator	-
G163CM_RS18910	4071557..4072927	-	1371	WP_231825958.1	MFS transporter	-
G163CM_RS18915	4073345..4074055	+	711	WP_015962550.1	DUF3053 domain-containing protein	-
G163CM_RS18920	4074132..4075109	-	978	WP_231825959.1	glyoxylate/hydroxypyruvate reductase GhrB	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Hok/gef cell toxic protein (5-46)

Sequences

Toxin

Protein

• Length: 51 a.a.
• Molecular weight: 5731.94 Da
• Isoelectric Point: 8.2819

>T226463 WP_144052219.1 NZ_CP087880:4070253-4070405 [Pseudocitrobacter corydidari]
MPQKYLLFGLVVICFTLLLFTWMVRDSLCELHIKQGNNELAAFLACGNKK

Nucleotide

• Length: 153 bp

>T226463 NZ_CP122496:966308-966643 [Escherichia coli]
ATGGTAAGCCGATACGTACCCGATATGGGCGATCTGATTTGGGTTGATTTTGACCCGACAAAAGGTAGCGAGCAAGCTGG
ACATCGTCCAGCTGTTGTCCTGAGTCCTTTCATGTACAACAACAAAACAGGTATGTGTCTGTGTGTTCCTTGTACAACGC
AATCAAAAGGATATCCGTTCGAAGTTGTTTTATCCGGTCAGGAACGTGATGGCGTAGCGTTAGCTGATCAGGTAAAAAGT
ATCGCCTGGCGGGCAAGAGGAGCAACGAAGAAAGGAACAGTTGCCCCAGAGGAATTACAACTCATTAAAGCCAAAATTAA
CGTACTGATTGGGTAG

Antitoxin

Nucleotide

• Length: 55 bp

>AT226463 NZ_CP087880:c4070202-4070148 [Pseudocitrobacter corydidari]
GTTGATGCATAGAGGGGCCTCACTTTGATTTATAGTCAGGTGGGGCTTTTCTCTG

Structures

Antitoxin