Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yefM-yoeB (relBE)/YoeB-YefM
Location 2822232..2822740 Replicon chromosome
Accession NZ_CP087879
Organism Agromyces marinus strain DSM 26151

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag DSM26151_RS13195 Protein ID WP_234659980.1
Coordinates 2822232..2822492 (-) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag DSM26151_RS13200 Protein ID WP_234659981.1
Coordinates 2822489..2822740 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
DSM26151_RS13150 (DSM26151_26300) 2817402..2817821 - 420 WP_234659971.1 hypothetical protein -
DSM26151_RS13155 (DSM26151_26310) 2817875..2818591 - 717 WP_234659972.1 DUF2071 domain-containing protein -
DSM26151_RS13160 (DSM26151_26320) 2818693..2819205 + 513 WP_234659973.1 barstar family protein -
DSM26151_RS13165 (DSM26151_26330) 2819332..2819562 + 231 WP_234659974.1 hypothetical protein -
DSM26151_RS13170 (DSM26151_26340) 2819607..2819846 - 240 WP_234659975.1 BrnT family toxin -
DSM26151_RS13175 2819843..2820106 - 264 WP_234659976.1 ribbon-helix-helix protein, CopG family -
DSM26151_RS13180 (DSM26151_26350) 2820310..2820879 + 570 WP_234659977.1 hypothetical protein -
DSM26151_RS13185 (DSM26151_26360) 2820962..2821504 + 543 WP_234659978.1 helix-turn-helix domain-containing protein -
DSM26151_RS13190 2821508..2822086 + 579 WP_234659979.1 PIN domain-containing protein -
DSM26151_RS13195 (DSM26151_26390) 2822232..2822492 - 261 WP_234659980.1 Txe/YoeB family addiction module toxin Toxin
DSM26151_RS13200 (DSM26151_26400) 2822489..2822740 - 252 WP_234659981.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
DSM26151_RS13205 2822841..2823254 - 414 WP_234659982.1 hypothetical protein -
DSM26151_RS13210 (DSM26151_26410) 2823342..2823836 + 495 WP_234659983.1 hypothetical protein -
DSM26151_RS13215 2823891..2824394 + 504 WP_234659984.1 hypothetical protein -
DSM26151_RS15145 (DSM26151_26430) 2824454..2824582 - 129 WP_267963239.1 hypothetical protein -
DSM26151_RS13220 (DSM26151_26440) 2824782..2825018 + 237 WP_234659985.1 hypothetical protein -
DSM26151_RS13225 (DSM26151_26450) 2825069..2825473 - 405 WP_234659986.1 VapC toxin family PIN domain ribonuclease -
DSM26151_RS13230 (DSM26151_26460) 2825470..2825685 - 216 WP_234659987.1 type II toxin-antitoxin system VapB family antitoxin -
DSM26151_RS13235 (DSM26151_26480) 2826385..2826630 + 246 WP_234659988.1 ribbon-helix-helix domain-containing protein -
DSM26151_RS13240 (DSM26151_26490) 2826624..2826971 + 348 WP_234659989.1 type II toxin-antitoxin system PemK/MazF family toxin -
DSM26151_RS13245 (DSM26151_26500) 2827025..2827282 - 258 WP_234659990.1 type II toxin-antitoxin system RelE/ParE family toxin -
DSM26151_RS13250 (DSM26151_26510) 2827279..2827527 - 249 WP_234659991.1 type II toxin-antitoxin system Phd/YefM family antitoxin -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 2811792..2827849 16057


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(7-86)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10183.53 Da        Isoelectric Point: 7.3146

>T226434 WP_234659980.1 NZ_CP087879:c2822492-2822232 [Agromyces marinus]
VTRALAFDQNGWEDYVYWQTQDRKTLRRINVLIADVLRDPFAGIGKPEPLKHILSGAWSRRIDETNRLVYYVTDDHIVIL
QARDHY

Download         Length: 261 bp

>T226434 NZ_CP122492:268750-268980 [Escherichia coli]
CTGGATCAGCTATTTAAATCACCTTTACCTCAAGGAATCAAATGGACTGATATAGAATCTCTGGTTAAAGCGTTAGGCGG
AGAAATTAAGGAAGGTAGGGGGTCGCGCTGTAAGTTCATACTAAATATGAGCGTTGCGTGTTTCCATCGGCCTCATCCGT
CGCCAGATACCGATAAAGGCGCTGTAGAAAGCGTGCGTGACTGGTTACTAAGTATAGGGGTAAAACCATGA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9257.30 Da        Isoelectric Point: 4.8210

>AT226434 WP_234659981.1 NZ_CP087879:c2822740-2822489 [Agromyces marinus]
MSAITATEARKSLFGLIQQVNDDHTAVEVVSRHGNAVIMSKDDYDAITETAHLLRNPANAERLLDAIERARRGEFEQHDL
LEA

Download         Length: 252 bp

>AT226434 NZ_CP122492:268977-269336 [Escherichia coli]
ATGATCAAACTGAAGACGCCAAACTCTATGGAGATTGCCGGGCAACCTGCTGTTATCACTTACGTGCCAGAACTGAATGC
ATTTCGTGGCAAATTCCTGGGCTTGTCAGGTTATTGTGATTTTGTCTCTGACAGCATTCAGGGGCTGCAAAAAGAAGGGG
AACTTTCCCTGCGAGAGTATCTTGAGGATTGTAAAGCTGCGGGTATTGAGCCGTATGCGCGTACAGAAAAGATTAAGACC
TTTACGTTACGCTATCCAGAATCGCTGAGTGAACGCCTTAATAATGCGGCTGCGCAGCAACAAGTCTCTGTTAATACCTA
TATTATTGAAACACTGAATGAGCGTTTGAATCATTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References