Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/HigB-HigA |
| Location | 920075..920673 | Replicon | chromosome |
| Accession | NZ_CP087793 | ||
| Organism | Moraxella bovis strain SAM57959 | ||
Toxin (Protein)
| Gene name | higB | Uniprot ID | - |
| Locus tag | LP112_RS04895 | Protein ID | WP_078275306.1 |
| Coordinates | 920395..920673 (-) | Length | 93 a.a. |
Antitoxin (Protein)
| Gene name | graA | Uniprot ID | - |
| Locus tag | LP112_RS04890 | Protein ID | WP_078275307.1 |
| Coordinates | 920075..920380 (-) | Length | 102 a.a. |
Genomic Context
Location: 916596..916928 (333 bp)
Type: Others
Protein ID: WP_078275314.1
Type: Others
Protein ID: WP_078275314.1
Location: 916964..917353 (390 bp)
Type: Others
Protein ID: WP_078275313.1
Type: Others
Protein ID: WP_078275313.1
Location: 917350..918033 (684 bp)
Type: Others
Protein ID: WP_264676213.1
Type: Others
Protein ID: WP_264676213.1
Location: 918478..919074 (597 bp)
Type: Others
Protein ID: WP_264676214.1
Type: Others
Protein ID: WP_264676214.1
Location: 919071..919259 (189 bp)
Type: Others
Protein ID: WP_078275309.1
Type: Others
Protein ID: WP_078275309.1
Location: 919327..920103 (777 bp)
Type: Others
Protein ID: WP_078275308.1
Type: Others
Protein ID: WP_078275308.1
Location: 920759..921343 (585 bp)
Type: Others
Protein ID: WP_264676215.1
Type: Others
Protein ID: WP_264676215.1
Location: 918075..918305 (231 bp)
Type: Others
Protein ID: WP_078275311.1
Type: Others
Protein ID: WP_078275311.1
Location: 920075..920380 (306 bp)
Type: Antitoxin
Protein ID: WP_078275307.1
Type: Antitoxin
Protein ID: WP_078275307.1
Location: 920395..920673 (279 bp)
Type: Toxin
Protein ID: WP_078275306.1
Type: Toxin
Protein ID: WP_078275306.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LP112_RS04855 (LP112_04835) | 916596..916928 | + | 333 | WP_078275314.1 | phage tail protein | - |
| LP112_RS04860 (LP112_04840) | 916964..917353 | + | 390 | WP_078275313.1 | hypothetical protein | - |
| LP112_RS04865 (LP112_04845) | 917350..918033 | + | 684 | WP_264676213.1 | phage minor tail protein L | - |
| LP112_RS04870 (LP112_04850) | 918075..918305 | - | 231 | WP_078275311.1 | Arc family DNA-binding protein | - |
| LP112_RS04875 (LP112_04855) | 918478..919074 | + | 597 | WP_264676214.1 | antA/AntB antirepressor family protein | - |
| LP112_RS04880 (LP112_04860) | 919071..919259 | + | 189 | WP_078275309.1 | hypothetical protein | - |
| LP112_RS04885 (LP112_04865) | 919327..920103 | + | 777 | WP_078275308.1 | C40 family peptidase | - |
| LP112_RS04890 (LP112_04870) | 920075..920380 | - | 306 | WP_078275307.1 | HigA family addiction module antitoxin | Antitoxin |
| LP112_RS04895 (LP112_04875) | 920395..920673 | - | 279 | WP_078275306.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LP112_RS04900 (LP112_04880) | 920759..921343 | + | 585 | WP_264676215.1 | tail assembly protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 883346..929709 | 46363 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10491.92 Da Isoelectric Point: 5.0474
>T226162 WP_078275306.1 NZ_CP087793:c920673-920395 [Moraxella bovis]
MIQSFKCKDAQSLFETGSSRVFANFLSVATRKLTMLDNAVALADLRIPPANRLEKLTGDREGQYSIRINDQFRICFVWGD
DGVYDVEIVDYH
MIQSFKCKDAQSLFETGSSRVFANFLSVATRKLTMLDNAVALADLRIPPANRLEKLTGDREGQYSIRINDQFRICFVWGD
DGVYDVEIVDYH
Download Length: 279 bp
>T226162 NZ_CP122316:c2864073-2863816 [Escherichia coli]
ATGAATTTATCCCGTCAGGAACAACATACCTTACACGTTCTCGCTAAAGGTAGACGTATTGCGCACGTCCGCGATTCTTC
AGGCCGCGTCACTTCCGTTGAATGCTACAGCCGCGAAGGGCTGTTGCTGACCGACTGCACGCTCGCCGTCTTCAAAAAAC
TCAAAACCAAAAAACTTATCAAGTCCGTCAATGGCCAGCCCTATCGAATCAACACCACCGAGCTGAATAAAGTTCGCGCT
CAGCTCGATAATCGCTAA
ATGAATTTATCCCGTCAGGAACAACATACCTTACACGTTCTCGCTAAAGGTAGACGTATTGCGCACGTCCGCGATTCTTC
AGGCCGCGTCACTTCCGTTGAATGCTACAGCCGCGAAGGGCTGTTGCTGACCGACTGCACGCTCGCCGTCTTCAAAAAAC
TCAAAACCAAAAAACTTATCAAGTCCGTCAATGGCCAGCCCTATCGAATCAACACCACCGAGCTGAATAAAGTTCGCGCT
CAGCTCGATAATCGCTAA
Antitoxin
Download Length: 102 a.a. Molecular weight: 11173.81 Da Isoelectric Point: 7.3174
>AT226162 WP_078275307.1 NZ_CP087793:c920380-920075 [Moraxella bovis]
MFKNGMRPVHAGEVLREEYLIPMGMSATALANALGVTPARINDIVRQRRGVTADTALRLARYFGGTAQFWLNLQTTYELR
LAETTLGDSLDFISPHEVAHA
MFKNGMRPVHAGEVLREEYLIPMGMSATALANALGVTPARINDIVRQRRGVTADTALRLARYFGGTAQFWLNLQTTYELR
LAETTLGDSLDFISPHEVAHA
Download Length: 306 bp
>AT226162 NZ_CP122316:c2863804-2863259 [Escherichia coli]
ATGACAGTACACCACTTCACTTTTCATATCACAGATAAAAGTGATGCCAGTGATATCCGGGAAGTCGAAACCCGCGCATT
TGGCTTCAGCAAAGAAGCCGATTTAGTGGCCTCTTTACTTGAGGATGAAAGCGCGCGCCCCGCGTTATCGCTGCTAGCCC
GGTATGAAGGCAAAGCCGTCGGGCATATTTTATTTACCCGGGCAACCTTCAAAGGAGAAATGGATTCACCGTTGATGCAC
ATCCTCGCTCCCCTGGCGGTCATACCGGAATACCAAGGGATGGGCGTGGGAGGACGGTTGATACGCACTGGCATCGAGCA
CCTGAGGTTGATGGGCTGCCAGACGGTTTTTGTTCTCGGCCACGCCACCTATTACCCCCGACATGGGTTCGAACCCTGTG
CCGGAGACAAAGGCTATCCGGCACCTTATCCCATCCCGGAGGAGCACAAAGCCTGCTGGATGATGCAATCACTCACCGCT
CAGCCCATGACCCTGACCGGCCACATCCGGTGCGCAGACCCTGATGAAACCGGAGCACTGACGTGA
ATGACAGTACACCACTTCACTTTTCATATCACAGATAAAAGTGATGCCAGTGATATCCGGGAAGTCGAAACCCGCGCATT
TGGCTTCAGCAAAGAAGCCGATTTAGTGGCCTCTTTACTTGAGGATGAAAGCGCGCGCCCCGCGTTATCGCTGCTAGCCC
GGTATGAAGGCAAAGCCGTCGGGCATATTTTATTTACCCGGGCAACCTTCAAAGGAGAAATGGATTCACCGTTGATGCAC
ATCCTCGCTCCCCTGGCGGTCATACCGGAATACCAAGGGATGGGCGTGGGAGGACGGTTGATACGCACTGGCATCGAGCA
CCTGAGGTTGATGGGCTGCCAGACGGTTTTTGTTCTCGGCCACGCCACCTATTACCCCCGACATGGGTTCGAACCCTGTG
CCGGAGACAAAGGCTATCCGGCACCTTATCCCATCCCGGAGGAGCACAAAGCCTGCTGGATGATGCAATCACTCACCGCT
CAGCCCATGACCCTGACCGGCCACATCCGGTGCGCAGACCCTGATGAAACCGGAGCACTGACGTGA