Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/HigB-HigA
Location 316837..317435 Replicon chromosome
Accession NZ_CP087765
Organism Moraxella bovis strain SAM109246

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag LP096_RS01825 Protein ID WP_078275306.1
Coordinates 317157..317435 (-) Length 93 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag LP096_RS01820 Protein ID WP_276001721.1
Coordinates 316837..317127 (-) Length 97 a.a.

Genomic Context

LP096_RS01785LP096_RS01790LP096_RS01795LP096_RS01805LP096_RS01810LP096_RS01815LP096_RS01830LP096_RS01780LP096_RS01800LP096_RS01820LP096_RS01825
Location: 313322..313690 (369 bp)
Type: Others
Protein ID: WP_264689325.1
Location: 313726..314115 (390 bp)
Type: Others
Protein ID: WP_078275313.1
Location: 314112..314795 (684 bp)
Type: Others
Protein ID: WP_264676213.1
Location: 315240..315836 (597 bp)
Type: Others
Protein ID: WP_264676214.1
Location: 315833..316021 (189 bp)
Type: Others
Protein ID: WP_078275309.1
Location: 316089..316865 (777 bp)
Type: Others
Protein ID: WP_078275308.1
Location: 317521..318105 (585 bp)
Type: Others
Protein ID: WP_264676215.1
Location: 312743..312943 (201 bp)
Type: Others
Protein ID: WP_062501372.1
Location: 314837..315067 (231 bp)
Type: Others
Protein ID: WP_078275311.1
Location: 316837..317127 (291 bp)
Type: Antitoxin
Protein ID: WP_276001721.1
Location: 317157..317435 (279 bp)
Type: Toxin
Protein ID: WP_078275306.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
LP096_RS01780 (LP096_01750)312743..312943-201WP_062501372.1hypothetical protein-
LP096_RS01785 (LP096_01755)313322..313690+369WP_264689325.1phage tail protein-
LP096_RS01790 (LP096_01760)313726..314115+390WP_078275313.1hypothetical protein-
LP096_RS01795 (LP096_01765)314112..314795+684WP_264676213.1phage minor tail protein L-
LP096_RS01800 (LP096_01770)314837..315067-231WP_078275311.1Arc family DNA-binding protein-
LP096_RS01805 (LP096_01775)315240..315836+597WP_264676214.1antA/AntB antirepressor family protein-
LP096_RS01810 (LP096_01780)315833..316021+189WP_078275309.1hypothetical protein-
LP096_RS01815 (LP096_01785)316089..316865+777WP_078275308.1C40 family peptidase-
LP096_RS01820 (LP096_01790)316837..317127-291WP_276001721.1HigA family addiction module antitoxinAntitoxin
LP096_RS01825 (LP096_01795)317157..317435-279WP_078275306.1type II toxin-antitoxin system RelE/ParE family toxinToxin
LP096_RS01830 (LP096_01800)317521..318105+585WP_264676215.1tail assembly protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideProphage--285958..33284946891


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-1

(4-92)

Antitoxin

Toxin-antitoxin system, antidote protein, HigA

(1-90)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10491.92 Da        Isoelectric Point: 5.0474

>T226098 WP_078275306.1 NZ_CP087765:c317435-317157 [Moraxella bovis]
MIQSFKCKDAQSLFETGSSRVFANFLSVATRKLTMLDNAVALADLRIPPANRLEKLTGDREGQYSIRINDQFRICFVWGD
DGVYDVEIVDYH

Download         Length: 279 bp

>T226098 NZ_CP121861:2995874-2996620 [Bacillus stercoris]
ATGGTTTTATTCTTTCAGATCATGGTCTGGTGCATTGTGGCTGGACTGGGGTTATACGTGTATGCCACGTGGCGTTTCGA
AGCGAAGGTCAAAGAAAAAATGTCCGCCATCCGGAAAACATGGTATTTGCTGTTTGTTCTGGGCGCTATGGTATACTGGA
CATATGAGCCCACTTCCCTATTTACCCACTGGGATCGGTATCTTATTGTCGCAGTCAGCTTTGCTTTGATTGATGCTTTC
ATCTTCTTAAGTGCATACGTCAAAAAACTGGCTGGCAGCGAGCTTGAAACAGACACAAGAGAAATTCTTGAAGAAAACAA
CGAAATGCTCCACATGTATCTCAATCGGCTGAAAACATACCAATACCTATTGAAAAACGAACCGATCCATGTTTATTATG
GAAGTATAGATGCTTATGCTGAAGGCATTGATAAGCTGCTGAAAACCTATGCTGATAAAATGAACTTAACGGCTTCTCTT
TGCCAATATTCGACACAGGCTGATAAAGACCGGTTAACCGAGCATATGGATGATCCGGCAGATGTACAAACACGGCTCGA
TCGAAAGGATGTTTATTACGACCAATACGGAAAAATGGTTCTCATCCCTTTTACCATCGAGACAAAGAACTATGTCATCA
AGCTGACGTCTGACAGCATTGTCACGGAATTTGATTATTTGCTATTTACGTCATTAACGAGCATATATGATTTGGTGCTG
CCAATTGAGGAGGAAGGTGAAGGATAA

Antitoxin


Download         Length: 97 a.a.        Molecular weight: 10596.11 Da        Isoelectric Point: 6.7228

>AT226098 WP_276001721.1 NZ_CP087765:c317127-316837 [Moraxella bovis]
MRPVHAGEVLREEYLIPMGMSATALANALGVTPARINDIVRQRRGVTADTALRLARYFGGTAQFWLNLQTTYELRLAETT
LGDSLDFISPHEVAHA

Download         Length: 291 bp

>AT226098 NZ_CP121861:2996620-2996790 [Bacillus stercoris]
ATGGAACGTGCGTTTCAAAACGGATGCGAGCCCAGAGCGGCCAAACCGTTTAAAATCCTGAAAAAACGTTCAACCACCAG
TGTCGCAAGCTATCAAGTCAGTCCGCACACAGCAAGAATCTTCAAAGAAAACGAACGGCTGATTGACGAGTATAAACGAA
AAAAAGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
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Antitoxin

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Source
ID
Structure
No matching records found

References