Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/HigB-VapI |
| Location | 2312911..2313492 | Replicon | chromosome |
| Accession | NZ_CP087696 | ||
| Organism | Xylella taiwanensis strain PLS16B | ||
Toxin (Protein)
| Gene name | graT | Uniprot ID | Z9JLS9 |
| Locus tag | LPH57_RS09630 | Protein ID | WP_038270683.1 |
| Coordinates | 2312911..2313189 (+) | Length | 93 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | - |
| Locus tag | LPH57_RS09635 | Protein ID | WP_081755408.1 |
| Coordinates | 2313193..2313492 (+) | Length | 100 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LPH57_RS09595 (LPH57_09595) | 2308192..2309238 | + | 1047 | WP_038270717.1 | sulfate/molybdate ABC transporter ATP-binding protein | - |
| LPH57_RS09600 (LPH57_09600) | 2309925..2310521 | - | 597 | WP_162814073.1 | contractile injection system protein, VgrG/Pvc8 family | - |
| LPH57_RS09605 (LPH57_09605) | 2310733..2310789 | - | 57 | Protein_1895 | phage tail protein | - |
| LPH57_RS09610 (LPH57_09610) | 2310786..2311040 | - | 255 | WP_230428278.1 | phage tail protein | - |
| LPH57_RS09615 (LPH57_09615) | 2311113..2311517 | - | 405 | Protein_1897 | phage tail protein I | - |
| LPH57_RS09620 (LPH57_09620) | 2311588..2312481 | - | 894 | WP_038270682.1 | baseplate J/gp47 family protein | - |
| LPH57_RS09625 (LPH57_09625) | 2312481..2312810 | - | 330 | WP_230428175.1 | GPW/gp25 family protein | - |
| LPH57_RS09630 (LPH57_09630) | 2312911..2313189 | + | 279 | WP_038270683.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LPH57_RS09635 (LPH57_09635) | 2313193..2313492 | + | 300 | WP_081755408.1 | HigA family addiction module antitoxin | Antitoxin |
| LPH57_RS09640 (LPH57_09640) | 2313502..2313798 | - | 297 | WP_230428176.1 | phage baseplate assembly protein V | - |
| LPH57_RS09645 (LPH57_09645) | 2313752..2313961 | - | 210 | WP_230428177.1 | phage baseplate assembly protein V | - |
| LPH57_RS09650 (LPH57_09650) | 2313961..2314614 | - | 654 | WP_230428178.1 | hypothetical protein | - |
| LPH57_RS09655 (LPH57_09655) | 2314590..2315039 | - | 450 | WP_230428179.1 | hypothetical protein | - |
| LPH57_RS09660 (LPH57_09660) | 2315129..2315422 | - | 294 | WP_038270685.1 | hypothetical protein | - |
| LPH57_RS09665 (LPH57_09665) | 2315403..2315633 | - | 231 | WP_230428500.1 | hypothetical protein | - |
| LPH57_RS09670 (LPH57_09670) | 2315760..2316008 | - | 249 | WP_038270686.1 | hypothetical protein | - |
| LPH57_RS09675 (LPH57_09675) | 2316047..2317431 | - | 1385 | Protein_1909 | phage major capsid protein | - |
| LPH57_RS09680 (LPH57_09680) | 2317530..2317979 | - | 450 | WP_230428180.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2308144..2333276 | 25132 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10669.11 Da Isoelectric Point: 9.0910
>T226055 WP_038270683.1 NZ_CP087696:2312911-2313189 [Xylella taiwanensis]
MIKTFADQDTESLFNGSRVRRFIHIEAVARRKLIQLHAAATLSFLNAPPGNRLETLKGDRQGQHSIRINNQFRLCFIWEN
GDAYQVEIVDYH
MIKTFADQDTESLFNGSRVRRFIHIEAVARRKLIQLHAAATLSFLNAPPGNRLETLKGDRQGQHSIRINNQFRLCFIWEN
GDAYQVEIVDYH
Download Length: 279 bp
>T226055 NZ_CP121766:c4226936-4226646 [Pseudomonas aeruginosa]
ATGACCGAGCAAATTTATGATTATGACCCCGCGCAAGCGCTGGATAGCCCGGAGGCCATGGCTCTGTTCATCGCAGACGC
TTTGGATACTGGAGACACCGCCTATATCGCTAAGGCTATGGGAGTCGTGGCCCGCGCCAAGGGGATGACGGAGTTGGCCA
AGGAAACGGGTTTGGCCAGGGAGCAGCTTTACAAATCGTTTAGTGAGCGCGGGAACCCTACATTGAAAACCATGCTGGCA
GTAATGCGAGCTCTGGGAGTTGATCTGACCGCCCGCCCGCATGCTCAGTGA
ATGACCGAGCAAATTTATGATTATGACCCCGCGCAAGCGCTGGATAGCCCGGAGGCCATGGCTCTGTTCATCGCAGACGC
TTTGGATACTGGAGACACCGCCTATATCGCTAAGGCTATGGGAGTCGTGGCCCGCGCCAAGGGGATGACGGAGTTGGCCA
AGGAAACGGGTTTGGCCAGGGAGCAGCTTTACAAATCGTTTAGTGAGCGCGGGAACCCTACATTGAAAACCATGCTGGCA
GTAATGCGAGCTCTGGGAGTTGATCTGACCGCCCGCCCGCATGCTCAGTGA
Antitoxin
Download Length: 100 a.a. Molecular weight: 10980.69 Da Isoelectric Point: 9.0879
>AT226055 WP_081755408.1 NZ_CP087696:2313193-2313492 [Xylella taiwanensis]
MSMSKTLPPIHPGEILREEFMAPLGLSSNALAKAIGVTAARINEIVRERRGITADTALRLARYFGTDPQSWLNLEQHYAL
ECAKRDLGEALSRIHPRVA
MSMSKTLPPIHPGEILREEFMAPLGLSSNALAKAIGVTAARINEIVRERRGITADTALRLARYFGTDPQSWLNLEQHYAL
ECAKRDLGEALSRIHPRVA
Download Length: 300 bp
>AT226055 NZ_CP121766:c4227232-4226933 [Pseudomonas aeruginosa]
ATGGTTGAAGTCAAACAAACCGCCACTTTCATGGCATGGGAAAGCAAGCTAAAGGATCGGCGGGCAAAGGCCGTGATCGC
CGCCCGTATCTTCCGATTGGCGAATGGACTACCCGGCGATGTGTCACCAGTCGGCCAGGGTGTGAGCGAGTTGAGGATTC
ACTATGGCCCAGGCTATCGGGTGTACTTCCAGCAGCGCGGGACGGAAATCGTCATCCTGCTATGTGGTGGAGACAAGAGC
AGCCAGGCCAGGGATATAGAAATGGCGAAACGCCTGGCAAATGAGTGGAGGCCGCAATGA
ATGGTTGAAGTCAAACAAACCGCCACTTTCATGGCATGGGAAAGCAAGCTAAAGGATCGGCGGGCAAAGGCCGTGATCGC
CGCCCGTATCTTCCGATTGGCGAATGGACTACCCGGCGATGTGTCACCAGTCGGCCAGGGTGTGAGCGAGTTGAGGATTC
ACTATGGCCCAGGCTATCGGGTGTACTTCCAGCAGCGCGGGACGGAAATCGTCATCCTGCTATGTGGTGGAGACAAGAGC
AGCCAGGCCAGGGATATAGAAATGGCGAAACGCCTGGCAAATGAGTGGAGGCCGCAATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|