Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/HigB-VapI |
| Location | 1919260..1919841 | Replicon | chromosome |
| Accession | NZ_CP087695 | ||
| Organism | Xylella taiwanensis strain PLS434 | ||
Toxin (Protein)
| Gene name | graT | Uniprot ID | Z9JLS9 |
| Locus tag | LPH63_RS08095 | Protein ID | WP_038270683.1 |
| Coordinates | 1919563..1919841 (-) | Length | 93 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | - |
| Locus tag | LPH63_RS08090 | Protein ID | WP_081755408.1 |
| Coordinates | 1919260..1919559 (-) | Length | 100 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LPH63_RS08050 (LPH63_08050) | 1914773..1915222 | + | 450 | WP_230428180.1 | hypothetical protein | - |
| LPH63_RS08055 (LPH63_08055) | 1915321..1916705 | + | 1385 | Protein_1594 | phage major capsid protein | - |
| LPH63_RS08060 (LPH63_08060) | 1916744..1916992 | + | 249 | WP_038270686.1 | hypothetical protein | - |
| LPH63_RS08065 (LPH63_08065) | 1917119..1917349 | + | 231 | WP_230428500.1 | hypothetical protein | - |
| LPH63_RS08070 (LPH63_08070) | 1917330..1917623 | + | 294 | WP_038270685.1 | hypothetical protein | - |
| LPH63_RS08075 (LPH63_08075) | 1917713..1918162 | + | 450 | WP_230428179.1 | hypothetical protein | - |
| LPH63_RS08080 (LPH63_08080) | 1918138..1918791 | + | 654 | WP_230428178.1 | hypothetical protein | - |
| LPH63_RS12010 | 1918791..1919000 | + | 210 | WP_230428177.1 | phage baseplate assembly protein V | - |
| LPH63_RS12015 | 1918969..1919250 | + | 282 | WP_268980389.1 | phage baseplate assembly protein V | - |
| LPH63_RS08090 (LPH63_08090) | 1919260..1919559 | - | 300 | WP_081755408.1 | HigA family addiction module antitoxin | Antitoxin |
| LPH63_RS08095 (LPH63_08095) | 1919563..1919841 | - | 279 | WP_038270683.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LPH63_RS08100 (LPH63_08100) | 1919942..1920271 | + | 330 | WP_230428175.1 | GPW/gp25 family protein | - |
| LPH63_RS08105 (LPH63_08105) | 1920271..1921164 | + | 894 | WP_038270682.1 | baseplate J/gp47 family protein | - |
| LPH63_RS08110 (LPH63_08110) | 1921157..1921639 | + | 483 | Protein_1606 | phage tail protein I | - |
| LPH63_RS08115 (LPH63_08115) | 1921712..1921966 | + | 255 | WP_230428278.1 | phage tail protein | - |
| LPH63_RS08120 (LPH63_08120) | 1921963..1922043 | + | 81 | Protein_1608 | tail protein X | - |
| LPH63_RS08125 (LPH63_08125) | 1922231..1922827 | + | 597 | WP_162814073.1 | contractile injection system protein, VgrG/Pvc8 family | - |
| LPH63_RS08130 (LPH63_08130) | 1923514..1924560 | - | 1047 | WP_038270717.1 | sulfate/molybdate ABC transporter ATP-binding protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 1900305..1924608 | 24303 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10669.11 Da Isoelectric Point: 9.0910
>T226049 WP_038270683.1 NZ_CP087695:c1919841-1919563 [Xylella taiwanensis]
MIKTFADQDTESLFNGSRVRRFIHIEAVARRKLIQLHAAATLSFLNAPPGNRLETLKGDRQGQHSIRINNQFRLCFIWEN
GDAYQVEIVDYH
MIKTFADQDTESLFNGSRVRRFIHIEAVARRKLIQLHAAATLSFLNAPPGNRLETLKGDRQGQHSIRINNQFRLCFIWEN
GDAYQVEIVDYH
Download Length: 279 bp
>T226049 NZ_CP121700:5636197-5636508 [Methylobacterium indicum]
ATGACGTTGACCTTCTCGGACGATGCCTGGAGCGATTATGTGTTCTGGCAGGGTGAGAACACGGCCACGCTGGAGCGGAT
CAATGCTCTCATCAAAGAGATCAAACGCACGCCCTTCACCGGGACGGGCAAGCCCGAGCCTTTGAAGTTCAAGCTCAAGG
GTTGGTGGTCACGCCGGATCTCGGGGGAGCACCGTCTCGTCTATCGTGTGAGTGGTTCCGGCTCGACCCATACCCTCGAG
ATCGCGCAATGCCGATGGCACTACGATGACGAGAGCGATTCACGATCGCCTTGCAATCGCGAAGCTCTCTAG
ATGACGTTGACCTTCTCGGACGATGCCTGGAGCGATTATGTGTTCTGGCAGGGTGAGAACACGGCCACGCTGGAGCGGAT
CAATGCTCTCATCAAAGAGATCAAACGCACGCCCTTCACCGGGACGGGCAAGCCCGAGCCTTTGAAGTTCAAGCTCAAGG
GTTGGTGGTCACGCCGGATCTCGGGGGAGCACCGTCTCGTCTATCGTGTGAGTGGTTCCGGCTCGACCCATACCCTCGAG
ATCGCGCAATGCCGATGGCACTACGATGACGAGAGCGATTCACGATCGCCTTGCAATCGCGAAGCTCTCTAG
Antitoxin
Download Length: 100 a.a. Molecular weight: 10980.69 Da Isoelectric Point: 9.0879
>AT226049 WP_081755408.1 NZ_CP087695:c1919559-1919260 [Xylella taiwanensis]
MSMSKTLPPIHPGEILREEFMAPLGLSSNALAKAIGVTAARINEIVRERRGITADTALRLARYFGTDPQSWLNLEQHYAL
ECAKRDLGEALSRIHPRVA
MSMSKTLPPIHPGEILREEFMAPLGLSSNALAKAIGVTAARINEIVRERRGITADTALRLARYFGTDPQSWLNLEQHYAL
ECAKRDLGEALSRIHPRVA
Download Length: 300 bp
>AT226049 NZ_CP121700:5635918-5636181 [Methylobacterium indicum]
ATGACTCATGTGAGCCTGACCGACTTTCGACAGAGCATCGCCGCCCATTTCGACAGGGTCGAGCGTGACCGCGAAGAGCT
GGTCGTCACCCGCCAGGGTCACGAACCGCTGGTGTTGCTGCCACTCGCCGAGTTGGAGAGCCTCCGGGAGACCCTGCACC
TGCTGGGCACGCCCGCCAATGCCCGGCGACTGATGCGGTCGATTGAGCAGCTCGACGCAGGTCAAACGATCGAACGCGCG
CTCATCGAACCCGATCAGCCCTAA
ATGACTCATGTGAGCCTGACCGACTTTCGACAGAGCATCGCCGCCCATTTCGACAGGGTCGAGCGTGACCGCGAAGAGCT
GGTCGTCACCCGCCAGGGTCACGAACCGCTGGTGTTGCTGCCACTCGCCGAGTTGGAGAGCCTCCGGGAGACCCTGCACC
TGCTGGGCACGCCCGCCAATGCCCGGCGACTGATGCGGTCGATTGAGCAGCTCGACGCAGGTCAAACGATCGAACGCGCG
CTCATCGAACCCGATCAGCCCTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|