Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/HigB-VapI |
| Location | 2313039..2313620 | Replicon | chromosome |
| Accession | NZ_CP087693 | ||
| Organism | Xylella taiwanensis strain PLS429 | ||
Toxin (Protein)
| Gene name | graT | Uniprot ID | Z9JLS9 |
| Locus tag | LPH62_RS09560 | Protein ID | WP_038270683.1 |
| Coordinates | 2313039..2313317 (+) | Length | 93 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | - |
| Locus tag | LPH62_RS09565 | Protein ID | WP_081755408.1 |
| Coordinates | 2313321..2313620 (+) | Length | 100 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LPH62_RS09525 (LPH62_09525) | 2308320..2309366 | + | 1047 | WP_038270717.1 | sulfate/molybdate ABC transporter ATP-binding protein | - |
| LPH62_RS09530 (LPH62_09530) | 2310053..2310649 | - | 597 | WP_162814073.1 | contractile injection system protein, VgrG/Pvc8 family | - |
| LPH62_RS09535 (LPH62_09535) | 2310837..2310917 | - | 81 | Protein_1878 | tail protein X | - |
| LPH62_RS09540 (LPH62_09540) | 2310914..2311168 | - | 255 | WP_230428278.1 | phage tail protein | - |
| LPH62_RS09545 (LPH62_09545) | 2311241..2311723 | - | 483 | Protein_1880 | phage tail protein I | - |
| LPH62_RS09550 (LPH62_09550) | 2311716..2312609 | - | 894 | WP_038270682.1 | baseplate J/gp47 family protein | - |
| LPH62_RS09555 (LPH62_09555) | 2312609..2312938 | - | 330 | WP_230428175.1 | GPW/gp25 family protein | - |
| LPH62_RS09560 (LPH62_09560) | 2313039..2313317 | + | 279 | WP_038270683.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LPH62_RS09565 (LPH62_09565) | 2313321..2313620 | + | 300 | WP_081755408.1 | HigA family addiction module antitoxin | Antitoxin |
| LPH62_RS09570 (LPH62_09570) | 2313630..2313926 | - | 297 | WP_230428176.1 | phage baseplate assembly protein V | - |
| LPH62_RS09575 (LPH62_09575) | 2313880..2314089 | - | 210 | WP_230428177.1 | phage baseplate assembly protein V | - |
| LPH62_RS09580 (LPH62_09580) | 2314089..2314742 | - | 654 | WP_230428178.1 | hypothetical protein | - |
| LPH62_RS09585 (LPH62_09585) | 2314718..2315134 | - | 417 | WP_230428499.1 | hypothetical protein | - |
| LPH62_RS09590 (LPH62_09590) | 2315257..2315550 | - | 294 | WP_038270685.1 | hypothetical protein | - |
| LPH62_RS09595 (LPH62_09595) | 2315888..2316136 | - | 249 | WP_038270686.1 | hypothetical protein | - |
| LPH62_RS09600 (LPH62_09600) | 2316175..2317559 | - | 1385 | Protein_1891 | phage major capsid protein | - |
| LPH62_RS09605 (LPH62_09605) | 2317658..2318107 | - | 450 | WP_230428180.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2308272..2334891 | 26619 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10669.11 Da Isoelectric Point: 9.0910
>T226037 WP_038270683.1 NZ_CP087693:2313039-2313317 [Xylella taiwanensis]
MIKTFADQDTESLFNGSRVRRFIHIEAVARRKLIQLHAAATLSFLNAPPGNRLETLKGDRQGQHSIRINNQFRLCFIWEN
GDAYQVEIVDYH
MIKTFADQDTESLFNGSRVRRFIHIEAVARRKLIQLHAAATLSFLNAPPGNRLETLKGDRQGQHSIRINNQFRLCFIWEN
GDAYQVEIVDYH
Download Length: 279 bp
>T226037 NZ_CP121695:8335513-8335851 [Bradyrhizobium sp. CB1650]
ATGCCACCCTTTAGGCAGGGGGATGTCGTTAGGGTTCCTTTCCCGTACACAGATCGATCGACTCGTCAGCACCGCCCGGC
ACTCGTTGTGTCCACAGGAGGCATCGGGGAAAACGAGAACCTCATCTGGGTGGTGATGATCACGAGTGCGGAAAACAGAA
CCTGGCCGGGGGATCTTGCTATCGGTCGTTACGAAGAGGCCGGTCTCCCTGCTCCCTCCATCATTCGATCCTGTAAGATC
GCGACGATCGAGGCACGCCACGCGGAAAGGCTCGGTCGTATCAAGCCTCGTTTGACGACCGAAGTCGTATCGGCGATACG
CAGCATTCTGGGTAGCTGA
ATGCCACCCTTTAGGCAGGGGGATGTCGTTAGGGTTCCTTTCCCGTACACAGATCGATCGACTCGTCAGCACCGCCCGGC
ACTCGTTGTGTCCACAGGAGGCATCGGGGAAAACGAGAACCTCATCTGGGTGGTGATGATCACGAGTGCGGAAAACAGAA
CCTGGCCGGGGGATCTTGCTATCGGTCGTTACGAAGAGGCCGGTCTCCCTGCTCCCTCCATCATTCGATCCTGTAAGATC
GCGACGATCGAGGCACGCCACGCGGAAAGGCTCGGTCGTATCAAGCCTCGTTTGACGACCGAAGTCGTATCGGCGATACG
CAGCATTCTGGGTAGCTGA
Antitoxin
Download Length: 100 a.a. Molecular weight: 10980.69 Da Isoelectric Point: 9.0879
>AT226037 WP_081755408.1 NZ_CP087693:2313321-2313620 [Xylella taiwanensis]
MSMSKTLPPIHPGEILREEFMAPLGLSSNALAKAIGVTAARINEIVRERRGITADTALRLARYFGTDPQSWLNLEQHYAL
ECAKRDLGEALSRIHPRVA
MSMSKTLPPIHPGEILREEFMAPLGLSSNALAKAIGVTAARINEIVRERRGITADTALRLARYFGTDPQSWLNLEQHYAL
ECAKRDLGEALSRIHPRVA
Download Length: 300 bp
>AT226037 NZ_CP121695:8335311-8335526 [Bradyrhizobium sp. CB1650]
ATGATTACCAGTAAACTTACAACCAAAGCTCAAACCACGATCCCCCAGGCAGTCCGGTCCGCTCTGCATCTGAAGGAGGG
GGACGAGATCGCTTATACGATCACTGGTGATAAGGTCGTCATGACAAAGGCCGAGCTTACTCTGGTTGATGATCCCTTCG
CCACCTTTAGCGAATGGGACAGCGAGGCAGATCGGAAAGCCTATGCCACCCTTTAG
ATGATTACCAGTAAACTTACAACCAAAGCTCAAACCACGATCCCCCAGGCAGTCCGGTCCGCTCTGCATCTGAAGGAGGG
GGACGAGATCGCTTATACGATCACTGGTGATAAGGTCGTCATGACAAAGGCCGAGCTTACTCTGGTTGATGATCCCTTCG
CCACCTTTAGCGAATGGGACAGCGAGGCAGATCGGAAAGCCTATGCCACCCTTTAG
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|