Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/HigB-VapI |
| Location | 2313076..2313657 | Replicon | chromosome |
| Accession | NZ_CP087692 | ||
| Organism | Xylella taiwanensis strain PLS427 | ||
Toxin (Protein)
| Gene name | graT | Uniprot ID | Z9JLS9 |
| Locus tag | LPH51_RS09590 | Protein ID | WP_038270683.1 |
| Coordinates | 2313076..2313354 (+) | Length | 93 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | - |
| Locus tag | LPH51_RS09595 | Protein ID | WP_081755408.1 |
| Coordinates | 2313358..2313657 (+) | Length | 100 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LPH51_RS09555 (LPH51_09555) | 2308357..2309403 | + | 1047 | WP_038270717.1 | sulfate/molybdate ABC transporter ATP-binding protein | - |
| LPH51_RS09560 (LPH51_09560) | 2310090..2310614 | - | 525 | WP_230439259.1 | contractile injection system protein, VgrG/Pvc8 family | - |
| LPH51_RS09565 (LPH51_09565) | 2310898..2310954 | - | 57 | Protein_1886 | phage tail protein | - |
| LPH51_RS09570 (LPH51_09570) | 2310951..2311205 | - | 255 | WP_230428278.1 | phage tail protein | - |
| LPH51_RS09575 (LPH51_09575) | 2311278..2311682 | - | 405 | Protein_1888 | phage tail protein I | - |
| LPH51_RS09580 (LPH51_09580) | 2311753..2312646 | - | 894 | WP_038270682.1 | baseplate J/gp47 family protein | - |
| LPH51_RS09585 (LPH51_09585) | 2312646..2312975 | - | 330 | WP_230428175.1 | GPW/gp25 family protein | - |
| LPH51_RS09590 (LPH51_09590) | 2313076..2313354 | + | 279 | WP_038270683.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LPH51_RS09595 (LPH51_09595) | 2313358..2313657 | + | 300 | WP_081755408.1 | HigA family addiction module antitoxin | Antitoxin |
| LPH51_RS09600 (LPH51_09600) | 2313667..2313963 | - | 297 | WP_230428176.1 | phage baseplate assembly protein V | - |
| LPH51_RS09605 (LPH51_09605) | 2313917..2314126 | - | 210 | WP_230428177.1 | phage baseplate assembly protein V | - |
| LPH51_RS09610 (LPH51_09610) | 2314126..2314779 | - | 654 | WP_230428178.1 | hypothetical protein | - |
| LPH51_RS09615 (LPH51_09615) | 2314755..2315204 | - | 450 | WP_230428179.1 | hypothetical protein | - |
| LPH51_RS09620 (LPH51_09620) | 2315294..2315587 | - | 294 | WP_038270685.1 | hypothetical protein | - |
| LPH51_RS09625 (LPH51_09625) | 2315568..2315798 | - | 231 | WP_230428500.1 | hypothetical protein | - |
| LPH51_RS09630 (LPH51_09630) | 2315925..2316173 | - | 249 | WP_038270686.1 | hypothetical protein | - |
| LPH51_RS09635 (LPH51_09635) | 2316212..2317596 | - | 1385 | Protein_1900 | phage major capsid protein | - |
| LPH51_RS09640 (LPH51_09640) | 2317695..2318144 | - | 450 | WP_230428180.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2308309..2349030 | 40721 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10669.11 Da Isoelectric Point: 9.0910
>T226031 WP_038270683.1 NZ_CP087692:2313076-2313354 [Xylella taiwanensis]
MIKTFADQDTESLFNGSRVRRFIHIEAVARRKLIQLHAAATLSFLNAPPGNRLETLKGDRQGQHSIRINNQFRLCFIWEN
GDAYQVEIVDYH
MIKTFADQDTESLFNGSRVRRFIHIEAVARRKLIQLHAAATLSFLNAPPGNRLETLKGDRQGQHSIRINNQFRLCFIWEN
GDAYQVEIVDYH
Download Length: 279 bp
>T226031 NZ_CP121679:c3966111-3965689 [Ancylobacter sp. WKF20]
ATGATCCTTCTCGACACCAATGTCATCTCGGAGGCGATGAAGCCCACGCCCGACGACACCGTGCGGGCGTGGCTCGACGA
TCAGGCGGCCGAGACGCTCTATCTCTCCAGCGTCACCATCGCCGAACTGTTGTACGGCATCGGTGCGCTGCCCGCGGGCA
AGCGCAAGGACAGGCTCACGGAGGCCCTGGACGGGGTGATGGAGCTGTTCGCCGACCGTGTCCTGCCGTTCGATGTCGCT
GCCGCACGACGCTATGCCGACCTCGCCGTGAAGGCGCGTGCGACCGGCAAGGGCTTTCCGACGCCCGACGGCTATATCGC
GGCGATCGCAGCCTCTCGGGGCTTTGCTGTGGCCACGCGCGATACCAGCGCATTCGACGCCGCCGGTGTGGCGGTCATCA
ATCCGTGGAACGTGGAACGCTGA
ATGATCCTTCTCGACACCAATGTCATCTCGGAGGCGATGAAGCCCACGCCCGACGACACCGTGCGGGCGTGGCTCGACGA
TCAGGCGGCCGAGACGCTCTATCTCTCCAGCGTCACCATCGCCGAACTGTTGTACGGCATCGGTGCGCTGCCCGCGGGCA
AGCGCAAGGACAGGCTCACGGAGGCCCTGGACGGGGTGATGGAGCTGTTCGCCGACCGTGTCCTGCCGTTCGATGTCGCT
GCCGCACGACGCTATGCCGACCTCGCCGTGAAGGCGCGTGCGACCGGCAAGGGCTTTCCGACGCCCGACGGCTATATCGC
GGCGATCGCAGCCTCTCGGGGCTTTGCTGTGGCCACGCGCGATACCAGCGCATTCGACGCCGCCGGTGTGGCGGTCATCA
ATCCGTGGAACGTGGAACGCTGA
Antitoxin
Download Length: 100 a.a. Molecular weight: 10980.69 Da Isoelectric Point: 9.0879
>AT226031 WP_081755408.1 NZ_CP087692:2313358-2313657 [Xylella taiwanensis]
MSMSKTLPPIHPGEILREEFMAPLGLSSNALAKAIGVTAARINEIVRERRGITADTALRLARYFGTDPQSWLNLEQHYAL
ECAKRDLGEALSRIHPRVA
MSMSKTLPPIHPGEILREEFMAPLGLSSNALAKAIGVTAARINEIVRERRGITADTALRLARYFGTDPQSWLNLEQHYAL
ECAKRDLGEALSRIHPRVA
Download Length: 300 bp
>AT226031 NZ_CP121679:c3966362-3966108 [Ancylobacter sp. WKF20]
ATGCCCGCAGTGACGATCCGCAACCTATCCGAGGCAACGCACCGCGCCTTGAAGGTGCGCGCGGCCCAGCATGGCCGCAG
CACCGAAGCTGAGATGCGCGACATCCTGGAGAGCGCCGTTCGCCCTGACACGCGCCTCCGGCTCGGGACGGAGCTCGCGG
AGCGCACCCGCCGCCTCGGCCTGACCAATGAGGACATCGACGCCCTCAACCCGGCGCGCGACAGGACGCCTGCCGAGCCC
ATGAGCTTCGAATGA
ATGCCCGCAGTGACGATCCGCAACCTATCCGAGGCAACGCACCGCGCCTTGAAGGTGCGCGCGGCCCAGCATGGCCGCAG
CACCGAAGCTGAGATGCGCGACATCCTGGAGAGCGCCGTTCGCCCTGACACGCGCCTCCGGCTCGGGACGGAGCTCGCGG
AGCGCACCCGCCGCCTCGGCCTGACCAATGAGGACATCGACGCCCTCAACCCGGCGCGCGACAGGACGCCTGCCGAGCCC
ATGAGCTTCGAATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|