Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | DinJ-YafQ (relBE)/YafQ-RelB |
| Location | 1455225..1455757 | Replicon | chromosome |
| Accession | NZ_CP087691 | ||
| Organism | Xylella taiwanensis strain PLS422 | ||
Toxin (Protein)
| Gene name | yafQ | Uniprot ID | Z9JHK5 |
| Locus tag | LPH48_RS06375 | Protein ID | WP_038272512.1 |
| Coordinates | 1455225..1455497 (-) | Length | 91 a.a. |
Antitoxin (Protein)
| Gene name | dinJ | Uniprot ID | Z9JHR3 |
| Locus tag | LPH48_RS06380 | Protein ID | WP_038272513.1 |
| Coordinates | 1455497..1455757 (-) | Length | 87 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LPH48_RS06325 (LPH48_06325) | 1451462..1451698 | - | 237 | WP_230428212.1 | major capsid protein | - |
| LPH48_RS06330 (LPH48_06330) | 1451707..1451913 | - | 207 | WP_038273075.1 | hypothetical protein | - |
| LPH48_RS06335 (LPH48_06335) | 1451916..1452230 | - | 315 | WP_230428211.1 | hypothetical protein | - |
| LPH48_RS06340 (LPH48_06340) | 1452506..1453093 | - | 588 | WP_038273076.1 | hypothetical protein | - |
| LPH48_RS06345 (LPH48_06345) | 1453290..1453433 | - | 144 | WP_160165233.1 | hypothetical protein | - |
| LPH48_RS06350 (LPH48_06350) | 1453553..1453753 | - | 201 | WP_038273077.1 | hypothetical protein | - |
| LPH48_RS06355 (LPH48_06355) | 1453802..1454065 | - | 264 | WP_162814095.1 | hypothetical protein | - |
| LPH48_RS06360 (LPH48_06360) | 1454069..1454230 | - | 162 | WP_160165182.1 | hypothetical protein | - |
| LPH48_RS06365 (LPH48_06365) | 1454319..1454786 | + | 468 | WP_162814096.1 | DUF3693 domain-containing protein | - |
| LPH48_RS06370 (LPH48_06370) | 1454845..1455189 | + | 345 | WP_038272511.1 | DUF3653 domain-containing protein | - |
| LPH48_RS06375 (LPH48_06375) | 1455225..1455497 | - | 273 | WP_038272512.1 | type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family | Toxin |
| LPH48_RS06380 (LPH48_06380) | 1455497..1455757 | - | 261 | WP_038272513.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| LPH48_RS06385 (LPH48_06385) | 1455846..1456973 | - | 1128 | WP_114867127.1 | zonular occludens toxin domain-containing protein | - |
| LPH48_RS06390 (LPH48_06390) | 1456986..1457330 | - | 345 | WP_038273069.1 | DUF2523 family protein | - |
| LPH48_RS06395 (LPH48_06395) | 1457333..1458718 | - | 1386 | WP_230428213.1 | furin-like repeat-containing protein | - |
| LPH48_RS06400 (LPH48_06400) | 1458898..1459134 | - | 237 | WP_230428212.1 | major capsid protein | - |
| LPH48_RS06405 (LPH48_06405) | 1459143..1459349 | - | 207 | WP_038273075.1 | hypothetical protein | - |
| LPH48_RS06410 (LPH48_06410) | 1459352..1459666 | - | 315 | WP_230428211.1 | hypothetical protein | - |
| LPH48_RS06415 (LPH48_06415) | 1459942..1460529 | - | 588 | WP_038273076.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 1414840..1471098 | 56258 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 91 a.a. Molecular weight: 10638.26 Da Isoelectric Point: 9.9110
>T226025 WP_038272512.1 NZ_CP087691:c1455497-1455225 [Xylella taiwanensis]
MRRPAYSSQFKRDVRVSQKRGKDIEKLKILITLLIEGSPLPAMYLDHPLKGQWRSFRDAHVEPDWLLIYKVDGDVVRFER
TGRHADLFDD
MRRPAYSSQFKRDVRVSQKRGKDIEKLKILITLLIEGSPLPAMYLDHPLKGQWRSFRDAHVEPDWLLIYKVDGDVVRFER
TGRHADLFDD
Download Length: 273 bp
>T226025 NZ_CP121668:7703679-7704101 [Bradyrhizobium sp. CB2312]
GTGAACCTGCTGCTCGACACCAACGTGCTGTCGGAGGTTCGGCGGCCTGCGCCTTCGCTGAAAGTCCTGGCGTGGCTCGA
TACGATCGACGAGGACCGTGCGTTCATCAGCGTCGCATCAATCGCTGAGCTTCGCCGCGGCATCGCATTGCTGAAGGACG
GCCGCCGGCGCACAGCGTTAGCCGCCTGGCTTGCCCACGACCTGCCGGCGCGGTTTGCCGAGCGAGTCCTGCCGATCGAT
CACGCCGTGGCGGATCGCTGGGGCGACCTGATGGCGGAGAGCCGCAGAACAGGAGTTGCGCTGTCTGTCATGGACGGCTT
CTTTGCGGCGACCGCGCTTGCGAACAGCCTCACGCTCGTCACGCGCAACGTGAAGGATTTCGCGGCCTTGGGCGTCCCGC
TGCTCAATCCGTGGGACGCCTAA
GTGAACCTGCTGCTCGACACCAACGTGCTGTCGGAGGTTCGGCGGCCTGCGCCTTCGCTGAAAGTCCTGGCGTGGCTCGA
TACGATCGACGAGGACCGTGCGTTCATCAGCGTCGCATCAATCGCTGAGCTTCGCCGCGGCATCGCATTGCTGAAGGACG
GCCGCCGGCGCACAGCGTTAGCCGCCTGGCTTGCCCACGACCTGCCGGCGCGGTTTGCCGAGCGAGTCCTGCCGATCGAT
CACGCCGTGGCGGATCGCTGGGGCGACCTGATGGCGGAGAGCCGCAGAACAGGAGTTGCGCTGTCTGTCATGGACGGCTT
CTTTGCGGCGACCGCGCTTGCGAACAGCCTCACGCTCGTCACGCGCAACGTGAAGGATTTCGCGGCCTTGGGCGTCCCGC
TGCTCAATCCGTGGGACGCCTAA
Antitoxin
Download Length: 87 a.a. Molecular weight: 9440.91 Da Isoelectric Point: 4.8047
>AT226025 WP_038272513.1 NZ_CP087691:c1455757-1455497 [Xylella taiwanensis]
MAANALVRARVDEALKDEAASVLATMGLTVSDLIRITLTKVAREKMLPFEMHSPNRLTVETFVKSECGEDVHYAESADAM
FKDLGI
MAANALVRARVDEALKDEAASVLATMGLTVSDLIRITLTKVAREKMLPFEMHSPNRLTVETFVKSECGEDVHYAESADAM
FKDLGI
Download Length: 261 bp
>AT226025 NZ_CP121668:7703398-7703682 [Bradyrhizobium sp. CB2312]
ATGGCTGACCATAACACTGCGCCCGACACGCCTCCGATCAATGACACCTGGACCCTTGCGAATGCCAAGGCACGGCTGTC
CGAACTGGTAGACCGCGCCCAAACGGGCCCGCAGGTCATCACCCGTCACGGCAAGCCGAATGCCGTAGTCGTTTCCGCCC
AGGAATGGGCGCGCAAGACAGCACGCAAGGGCACTCTGGCCGAATTCCTGCTGGCCTCGCCGCTGCGTGGCGCCGACCTT
GAACTCGATCGCGTGCACGACACGCCACGCGACGAAATGCCGTGA
ATGGCTGACCATAACACTGCGCCCGACACGCCTCCGATCAATGACACCTGGACCCTTGCGAATGCCAAGGCACGGCTGTC
CGAACTGGTAGACCGCGCCCAAACGGGCCCGCAGGTCATCACCCGTCACGGCAAGCCGAATGCCGTAGTCGTTTCCGCCC
AGGAATGGGCGCGCAAGACAGCACGCAAGGGCACTCTGGCCGAATTCCTGCTGGCCTCGCCGCTGCGTGGCGCCGACCTT
GAACTCGATCGCGTGCACGACACGCCACGCGACGAAATGCCGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|