Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/HigB-VapI |
| Location | 905014..905595 | Replicon | chromosome |
| Accession | NZ_CP087691 | ||
| Organism | Xylella taiwanensis strain PLS422 | ||
Toxin (Protein)
| Gene name | graT | Uniprot ID | Z9JLS9 |
| Locus tag | LPH48_RS03830 | Protein ID | WP_038270683.1 |
| Coordinates | 905014..905292 (+) | Length | 93 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | - |
| Locus tag | LPH48_RS03835 | Protein ID | WP_081755408.1 |
| Coordinates | 905296..905595 (+) | Length | 100 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LPH48_RS03795 (LPH48_03795) | 900295..901341 | + | 1047 | WP_038270717.1 | sulfate/molybdate ABC transporter ATP-binding protein | - |
| LPH48_RS03800 (LPH48_03800) | 902028..902624 | - | 597 | WP_162814073.1 | contractile injection system protein, VgrG/Pvc8 family | - |
| LPH48_RS03805 (LPH48_03805) | 902836..902892 | - | 57 | Protein_740 | phage tail protein | - |
| LPH48_RS03810 (LPH48_03810) | 902889..903143 | - | 255 | WP_230428278.1 | phage tail protein | - |
| LPH48_RS03815 (LPH48_03815) | 903216..903620 | - | 405 | Protein_742 | phage tail protein I | - |
| LPH48_RS03820 (LPH48_03820) | 903691..904584 | - | 894 | WP_038270682.1 | baseplate J/gp47 family protein | - |
| LPH48_RS03825 (LPH48_03825) | 904584..904913 | - | 330 | WP_230428175.1 | GPW/gp25 family protein | - |
| LPH48_RS03830 (LPH48_03830) | 905014..905292 | + | 279 | WP_038270683.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LPH48_RS03835 (LPH48_03835) | 905296..905595 | + | 300 | WP_081755408.1 | HigA family addiction module antitoxin | Antitoxin |
| LPH48_RS03840 (LPH48_03840) | 905605..905901 | - | 297 | WP_230428176.1 | phage baseplate assembly protein V | - |
| LPH48_RS03845 (LPH48_03845) | 905855..906064 | - | 210 | WP_230428177.1 | phage baseplate assembly protein V | - |
| LPH48_RS03850 (LPH48_03850) | 906064..906717 | - | 654 | WP_230428178.1 | hypothetical protein | - |
| LPH48_RS03855 (LPH48_03855) | 906693..907142 | - | 450 | WP_230428179.1 | hypothetical protein | - |
| LPH48_RS03860 (LPH48_03860) | 907232..907525 | - | 294 | WP_038270685.1 | hypothetical protein | - |
| LPH48_RS03865 (LPH48_03865) | 907863..908111 | - | 249 | WP_038270686.1 | hypothetical protein | - |
| LPH48_RS03870 (LPH48_03870) | 908150..909534 | - | 1385 | Protein_753 | phage major capsid protein | - |
| LPH48_RS03875 (LPH48_03875) | 909633..910082 | - | 450 | WP_230428180.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 900247..940968 | 40721 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10669.11 Da Isoelectric Point: 9.0910
>T226022 WP_038270683.1 NZ_CP087691:905014-905292 [Xylella taiwanensis]
MIKTFADQDTESLFNGSRVRRFIHIEAVARRKLIQLHAAATLSFLNAPPGNRLETLKGDRQGQHSIRINNQFRLCFIWEN
GDAYQVEIVDYH
MIKTFADQDTESLFNGSRVRRFIHIEAVARRKLIQLHAAATLSFLNAPPGNRLETLKGDRQGQHSIRINNQFRLCFIWEN
GDAYQVEIVDYH
Download Length: 279 bp
>T226022 NZ_CP121667:7062081-7062518 [Bradyrhizobium pachyrhizi]
ATGAATGTCCTGCTCGATACCAACGTGCTGTCGGAGGTTCGCCGGCCGGCGCCCGATCCGAAAGTGCTCGCGTGGCTTGA
TACGATCGACGAGGACCGGGCCTTCATCAGCGTTGCGTCGATCGCCGAACTCCGGCGCGGTATTGCCCTGATGGACGACG
GCCGCCGTCGCGAGGCGCTTTCCGCCTGGCTCGCGGAGGATCTGCCGGCGCGCTTCGCCGGGCGGATTCTGTCGATCGAC
CCGGCGATCGCCGGGCGCTGGGGTGATCTGATGGCGCAAGCCCGACAGAGCGGCTTTGCGCTCTCGGTCATGGACGGTTT
TTTTGCGGCTACTGCTCTCGACCGGGAGCTCGTACTCGCGACTCGCAACACCAAGGATTTTGCGCCGCTGGGTGTGCCGC
TTTTGAACCCCTGGACCGATGAAGGAGCGCTGGGATGA
ATGAATGTCCTGCTCGATACCAACGTGCTGTCGGAGGTTCGCCGGCCGGCGCCCGATCCGAAAGTGCTCGCGTGGCTTGA
TACGATCGACGAGGACCGGGCCTTCATCAGCGTTGCGTCGATCGCCGAACTCCGGCGCGGTATTGCCCTGATGGACGACG
GCCGCCGTCGCGAGGCGCTTTCCGCCTGGCTCGCGGAGGATCTGCCGGCGCGCTTCGCCGGGCGGATTCTGTCGATCGAC
CCGGCGATCGCCGGGCGCTGGGGTGATCTGATGGCGCAAGCCCGACAGAGCGGCTTTGCGCTCTCGGTCATGGACGGTTT
TTTTGCGGCTACTGCTCTCGACCGGGAGCTCGTACTCGCGACTCGCAACACCAAGGATTTTGCGCCGCTGGGTGTGCCGC
TTTTGAACCCCTGGACCGATGAAGGAGCGCTGGGATGA
Antitoxin
Download Length: 100 a.a. Molecular weight: 10980.69 Da Isoelectric Point: 9.0879
>AT226022 WP_081755408.1 NZ_CP087691:905296-905595 [Xylella taiwanensis]
MSMSKTLPPIHPGEILREEFMAPLGLSSNALAKAIGVTAARINEIVRERRGITADTALRLARYFGTDPQSWLNLEQHYAL
ECAKRDLGEALSRIHPRVA
MSMSKTLPPIHPGEILREEFMAPLGLSSNALAKAIGVTAARINEIVRERRGITADTALRLARYFGTDPQSWLNLEQHYAL
ECAKRDLGEALSRIHPRVA
Download Length: 300 bp
>AT226022 NZ_CP121667:7061806-7062084 [Bradyrhizobium pachyrhizi]
GTGACAGCCTCCCGAAAGACCCCTGCCCCCGAAACCGACCATTGGACCGTGGCTGGCGCCAAGGCGCGCCTCTCCGAGGT
GATCGAACGCGCCCAGACCGATCCGCAGATCATTACCCGCTACGGCAAGCCCAGTGTCGTCATCGTCTCCGCCGAGGAAT
GGGCGCGCAAGACCGACCGCAAGGGCACGCTCGCCGAATTCCTGATGGCCTCGCCGCTGCGTGATGCCGATCTCGATCTC
GAGCGGGTTCGCGATCAGCCGCGCGACCTTGATCTATGA
GTGACAGCCTCCCGAAAGACCCCTGCCCCCGAAACCGACCATTGGACCGTGGCTGGCGCCAAGGCGCGCCTCTCCGAGGT
GATCGAACGCGCCCAGACCGATCCGCAGATCATTACCCGCTACGGCAAGCCCAGTGTCGTCATCGTCTCCGCCGAGGAAT
GGGCGCGCAAGACCGACCGCAAGGGCACGCTCGCCGAATTCCTGATGGCCTCGCCGCTGCGTGATGCCGATCTCGATCTC
GAGCGGGTTCGCGATCAGCCGCGCGACCTTGATCTATGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|