Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/HigB-VapI |
| Location | 2305498..2306079 | Replicon | chromosome |
| Accession | NZ_CP087689 | ||
| Organism | Xylella taiwanensis strain PLS415 | ||
Toxin (Protein)
| Gene name | graT | Uniprot ID | Z9JLS9 |
| Locus tag | LPH50_RS09505 | Protein ID | WP_038270683.1 |
| Coordinates | 2305498..2305776 (+) | Length | 93 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | - |
| Locus tag | LPH50_RS09510 | Protein ID | WP_081755408.1 |
| Coordinates | 2305780..2306079 (+) | Length | 100 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LPH50_RS09470 (LPH50_09470) | 2300779..2301825 | + | 1047 | WP_038270717.1 | sulfate/molybdate ABC transporter ATP-binding protein | - |
| LPH50_RS09475 (LPH50_09475) | 2302512..2303108 | - | 597 | WP_162814073.1 | contractile injection system protein, VgrG/Pvc8 family | - |
| LPH50_RS09480 (LPH50_09480) | 2303320..2303376 | - | 57 | Protein_1870 | phage tail protein | - |
| LPH50_RS09485 (LPH50_09485) | 2303373..2303627 | - | 255 | WP_230428278.1 | phage tail protein | - |
| LPH50_RS09490 (LPH50_09490) | 2303700..2304104 | - | 405 | Protein_1872 | phage tail protein I | - |
| LPH50_RS09495 (LPH50_09495) | 2304175..2305068 | - | 894 | WP_038270682.1 | baseplate J/gp47 family protein | - |
| LPH50_RS09500 (LPH50_09500) | 2305068..2305397 | - | 330 | WP_230428175.1 | GPW/gp25 family protein | - |
| LPH50_RS09505 (LPH50_09505) | 2305498..2305776 | + | 279 | WP_038270683.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LPH50_RS09510 (LPH50_09510) | 2305780..2306079 | + | 300 | WP_081755408.1 | HigA family addiction module antitoxin | Antitoxin |
| LPH50_RS09515 (LPH50_09515) | 2306089..2306385 | - | 297 | WP_230428176.1 | phage baseplate assembly protein V | - |
| LPH50_RS09520 (LPH50_09520) | 2306339..2306548 | - | 210 | WP_230428177.1 | phage baseplate assembly protein V | - |
| LPH50_RS09525 (LPH50_09525) | 2306548..2307201 | - | 654 | WP_230428178.1 | hypothetical protein | - |
| LPH50_RS09530 (LPH50_09530) | 2307177..2307626 | - | 450 | WP_230428179.1 | hypothetical protein | - |
| LPH50_RS09535 (LPH50_09535) | 2307716..2308009 | - | 294 | WP_038270685.1 | hypothetical protein | - |
| LPH50_RS09540 (LPH50_09540) | 2307990..2308220 | - | 231 | WP_230428500.1 | hypothetical protein | - |
| LPH50_RS09545 (LPH50_09545) | 2308347..2308595 | - | 249 | WP_038270686.1 | hypothetical protein | - |
| LPH50_RS09550 (LPH50_09550) | 2308634..2310018 | - | 1385 | Protein_1884 | phage major capsid protein | - |
| LPH50_RS09555 (LPH50_09555) | 2310117..2310566 | - | 450 | WP_230428180.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2300731..2327350 | 26619 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10669.11 Da Isoelectric Point: 9.0910
>T226013 WP_038270683.1 NZ_CP087689:2305498-2305776 [Xylella taiwanensis]
MIKTFADQDTESLFNGSRVRRFIHIEAVARRKLIQLHAAATLSFLNAPPGNRLETLKGDRQGQHSIRINNQFRLCFIWEN
GDAYQVEIVDYH
MIKTFADQDTESLFNGSRVRRFIHIEAVARRKLIQLHAAATLSFLNAPPGNRLETLKGDRQGQHSIRINNQFRLCFIWEN
GDAYQVEIVDYH
Download Length: 279 bp
>T226013 NZ_CP121662:421052-421456 [Rhizobium sp. CB3090]
ATGCGCGCGCTGCCTCCTTTTCTCGACACGAATGTTCTTCTCTATGCGTTTACAGACGATCAACGGGCACAAAAGGCGCA
GTTGCTGTTGGCGGAGCCGTTTACGATCAGCGTGCAGGCATTGAATGAATTCGCCAACGTCGCGCGTAAAAAACTCCATC
TGCCATGGAAGCGCATTCACGAAGCTATCCGGACGATAGTGGAATTGTCCACATCGGTTGTCGCGATTGATGAGAAAACA
ACCCTATCGGCGCTTAACTTGGCAGAGCGCTACAATTTTTCTTTTTATGATGCAGCCATGGTTGCCGCTGCTCTTCAGGC
CAATTGCGAGCGATACTATTCGGAGGACCTGCATGACTGCTTAATCGTCGAAACGAGGCTGACGATTATAAATCCGTTTA
GTTAA
ATGCGCGCGCTGCCTCCTTTTCTCGACACGAATGTTCTTCTCTATGCGTTTACAGACGATCAACGGGCACAAAAGGCGCA
GTTGCTGTTGGCGGAGCCGTTTACGATCAGCGTGCAGGCATTGAATGAATTCGCCAACGTCGCGCGTAAAAAACTCCATC
TGCCATGGAAGCGCATTCACGAAGCTATCCGGACGATAGTGGAATTGTCCACATCGGTTGTCGCGATTGATGAGAAAACA
ACCCTATCGGCGCTTAACTTGGCAGAGCGCTACAATTTTTCTTTTTATGATGCAGCCATGGTTGCCGCTGCTCTTCAGGC
CAATTGCGAGCGATACTATTCGGAGGACCTGCATGACTGCTTAATCGTCGAAACGAGGCTGACGATTATAAATCCGTTTA
GTTAA
Antitoxin
Download Length: 100 a.a. Molecular weight: 10980.69 Da Isoelectric Point: 9.0879
>AT226013 WP_081755408.1 NZ_CP087689:2305780-2306079 [Xylella taiwanensis]
MSMSKTLPPIHPGEILREEFMAPLGLSSNALAKAIGVTAARINEIVRERRGITADTALRLARYFGTDPQSWLNLEQHYAL
ECAKRDLGEALSRIHPRVA
MSMSKTLPPIHPGEILREEFMAPLGLSSNALAKAIGVTAARINEIVRERRGITADTALRLARYFGTDPQSWLNLEQHYAL
ECAKRDLGEALSRIHPRVA
Download Length: 300 bp
>AT226013 NZ_CP121662:420822-421052 [Rhizobium sp. CB3090]
ATGCAAGTTGCAAAATGGGGAAACAGCTTAGCTATCCGTATTCCTTCGGCAGTCGCGGAAGCCCTCGATTTGAAAGAAGG
TGATGACGTCGTCGTTCGTATCGGCGCGGATAGTGCTTTTGAGATCGAGCGGGATGACAGACGGCAGAAAGCGTTGGAAA
AAGTGAAATCGTTCAAGATCACGCTTCCTACTGATTGGAAATTTGATCGCGACGAGGCCAATTCCCGTTGA
ATGCAAGTTGCAAAATGGGGAAACAGCTTAGCTATCCGTATTCCTTCGGCAGTCGCGGAAGCCCTCGATTTGAAAGAAGG
TGATGACGTCGTCGTTCGTATCGGCGCGGATAGTGCTTTTGAGATCGAGCGGGATGACAGACGGCAGAAAGCGTTGGAAA
AAGTGAAATCGTTCAAGATCACGCTTCCTACTGATTGGAAATTTGATCGCGACGAGGCCAATTCCCGTTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|