Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/HigB-VapI |
| Location | 2305529..2306110 | Replicon | chromosome |
| Accession | NZ_CP087688 | ||
| Organism | Xylella taiwanensis strain PLS413 | ||
Toxin (Protein)
| Gene name | graT | Uniprot ID | Z9JLS9 |
| Locus tag | LPH64_RS09520 | Protein ID | WP_038270683.1 |
| Coordinates | 2305529..2305807 (+) | Length | 93 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | - |
| Locus tag | LPH64_RS09525 | Protein ID | WP_081755408.1 |
| Coordinates | 2305811..2306110 (+) | Length | 100 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LPH64_RS09485 (LPH64_09485) | 2300810..2301856 | + | 1047 | WP_038270717.1 | sulfate/molybdate ABC transporter ATP-binding protein | - |
| LPH64_RS09490 (LPH64_09490) | 2302543..2303139 | - | 597 | WP_162814073.1 | contractile injection system protein, VgrG/Pvc8 family | - |
| LPH64_RS09495 (LPH64_09495) | 2303351..2303407 | - | 57 | Protein_1870 | phage tail protein | - |
| LPH64_RS09500 (LPH64_09500) | 2303404..2303658 | - | 255 | WP_230428278.1 | phage tail protein | - |
| LPH64_RS09505 (LPH64_09505) | 2303731..2304213 | - | 483 | Protein_1872 | phage tail protein I | - |
| LPH64_RS09510 (LPH64_09510) | 2304206..2305099 | - | 894 | WP_038270682.1 | baseplate J/gp47 family protein | - |
| LPH64_RS09515 (LPH64_09515) | 2305099..2305428 | - | 330 | WP_230428175.1 | GPW/gp25 family protein | - |
| LPH64_RS09520 (LPH64_09520) | 2305529..2305807 | + | 279 | WP_038270683.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LPH64_RS09525 (LPH64_09525) | 2305811..2306110 | + | 300 | WP_081755408.1 | HigA family addiction module antitoxin | Antitoxin |
| LPH64_RS09530 (LPH64_09530) | 2306120..2306416 | - | 297 | WP_230428176.1 | phage baseplate assembly protein V | - |
| LPH64_RS09535 (LPH64_09535) | 2306370..2306579 | - | 210 | WP_230428177.1 | phage baseplate assembly protein V | - |
| LPH64_RS09540 (LPH64_09540) | 2306579..2307232 | - | 654 | WP_230428178.1 | hypothetical protein | - |
| LPH64_RS09545 (LPH64_09545) | 2307208..2307624 | - | 417 | WP_230428499.1 | hypothetical protein | - |
| LPH64_RS09550 (LPH64_09550) | 2307747..2308040 | - | 294 | WP_038270685.1 | hypothetical protein | - |
| LPH64_RS09555 (LPH64_09555) | 2308021..2308251 | - | 231 | WP_230428500.1 | hypothetical protein | - |
| LPH64_RS09560 (LPH64_09560) | 2308378..2308626 | - | 249 | WP_038270686.1 | hypothetical protein | - |
| LPH64_RS09565 (LPH64_09565) | 2308665..2310049 | - | 1385 | Protein_1884 | phage major capsid protein | - |
| LPH64_RS09570 (LPH64_09570) | 2310148..2310597 | - | 450 | WP_230428180.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2300762..2325894 | 25132 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10669.11 Da Isoelectric Point: 9.0910
>T226008 WP_038270683.1 NZ_CP087688:2305529-2305807 [Xylella taiwanensis]
MIKTFADQDTESLFNGSRVRRFIHIEAVARRKLIQLHAAATLSFLNAPPGNRLETLKGDRQGQHSIRINNQFRLCFIWEN
GDAYQVEIVDYH
MIKTFADQDTESLFNGSRVRRFIHIEAVARRKLIQLHAAATLSFLNAPPGNRLETLKGDRQGQHSIRINNQFRLCFIWEN
GDAYQVEIVDYH
Download Length: 279 bp
>T226008 NZ_CP121660:c174310-173924 [Sinorhizobium terangae]
ATGGTCATCGATACGTCGGCCATTGTCGCCGTCGCATTCAATGAGCCAGAAGCGGAAACCTACGAACGGAAAGTCATCGA
TGCTCCGCGGCGCTTCATCTCCGCCGCGACGGTTCTCGAACTCGCCATCGTAATCGAAGCCCGCCTCGGCGAAGCAGGTG
CCGCAGAGCTCGACCTATGGCTCTACAAGGCGGGTGTTGAAATCGTCGCTGTCGACGCAGAACAGATTGCCGTGGCTAGG
CGAGCCTGGCGAAGCTACGGCAAAGGCCGACATCCGGCAGGTCTGAACTACGGTGACTGTTTCTCCTATGCGCTGGCCAA
AACGCGCAATGAACCGCTGCTCTTCAAAGGCGATGATTTTTCGCGTACTGACATAGAGGCCGCATGA
ATGGTCATCGATACGTCGGCCATTGTCGCCGTCGCATTCAATGAGCCAGAAGCGGAAACCTACGAACGGAAAGTCATCGA
TGCTCCGCGGCGCTTCATCTCCGCCGCGACGGTTCTCGAACTCGCCATCGTAATCGAAGCCCGCCTCGGCGAAGCAGGTG
CCGCAGAGCTCGACCTATGGCTCTACAAGGCGGGTGTTGAAATCGTCGCTGTCGACGCAGAACAGATTGCCGTGGCTAGG
CGAGCCTGGCGAAGCTACGGCAAAGGCCGACATCCGGCAGGTCTGAACTACGGTGACTGTTTCTCCTATGCGCTGGCCAA
AACGCGCAATGAACCGCTGCTCTTCAAAGGCGATGATTTTTCGCGTACTGACATAGAGGCCGCATGA
Antitoxin
Download Length: 100 a.a. Molecular weight: 10980.69 Da Isoelectric Point: 9.0879
>AT226008 WP_081755408.1 NZ_CP087688:2305811-2306110 [Xylella taiwanensis]
MSMSKTLPPIHPGEILREEFMAPLGLSSNALAKAIGVTAARINEIVRERRGITADTALRLARYFGTDPQSWLNLEQHYAL
ECAKRDLGEALSRIHPRVA
MSMSKTLPPIHPGEILREEFMAPLGLSSNALAKAIGVTAARINEIVRERRGITADTALRLARYFGTDPQSWLNLEQHYAL
ECAKRDLGEALSRIHPRVA
Download Length: 300 bp
>AT226008 NZ_CP121660:c174564-174310 [Sinorhizobium terangae]
ATGCCACTGAGCATCAAAGATCCCGAGACGGAACGCCTTGCAAAGGCACTGGCCGAGAAGACCGGTGAGACCATCACCAT
GGCGACCCGGCGTGCACTGGAAGAGCGGCTGCGACGTCTCGCAAACGCAGCAAATCGGGATGTTCTTCTCGAGGAGCTTG
CCGCCAGCCGTAGACGCTGGAGCAAGCTGCCGGTGCTGGACAACCGCTCTGCTGACGAAATCCTGGGGTATGACGAAAAC
GGGACTCCCAACTGA
ATGCCACTGAGCATCAAAGATCCCGAGACGGAACGCCTTGCAAAGGCACTGGCCGAGAAGACCGGTGAGACCATCACCAT
GGCGACCCGGCGTGCACTGGAAGAGCGGCTGCGACGTCTCGCAAACGCAGCAAATCGGGATGTTCTTCTCGAGGAGCTTG
CCGCCAGCCGTAGACGCTGGAGCAAGCTGCCGGTGCTGGACAACCGCTCTGCTGACGAAATCCTGGGGTATGACGAAAAC
GGGACTCCCAACTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|