Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/HigB-VapI |
| Location | 2274922..2275503 | Replicon | chromosome |
| Accession | NZ_CP087685 | ||
| Organism | Xylella taiwanensis strain PLS4A | ||
Toxin (Protein)
| Gene name | graT | Uniprot ID | Z9JLS9 |
| Locus tag | LPH40_RS09345 | Protein ID | WP_038270683.1 |
| Coordinates | 2274922..2275200 (+) | Length | 93 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | - |
| Locus tag | LPH40_RS09350 | Protein ID | WP_081755408.1 |
| Coordinates | 2275204..2275503 (+) | Length | 100 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LPH40_RS09310 (LPH40_09310) | 2270203..2271249 | + | 1047 | WP_038270717.1 | sulfate/molybdate ABC transporter ATP-binding protein | - |
| LPH40_RS09315 (LPH40_09315) | 2271936..2272532 | - | 597 | WP_162814073.1 | contractile injection system protein, VgrG/Pvc8 family | - |
| LPH40_RS09320 (LPH40_09320) | 2272720..2272800 | - | 81 | Protein_1837 | tail protein X | - |
| LPH40_RS09325 (LPH40_09325) | 2272797..2273051 | - | 255 | WP_230428278.1 | phage tail protein | - |
| LPH40_RS09330 (LPH40_09330) | 2273124..2273606 | - | 483 | Protein_1839 | phage tail protein I | - |
| LPH40_RS09335 (LPH40_09335) | 2273599..2274492 | - | 894 | WP_038270682.1 | baseplate J/gp47 family protein | - |
| LPH40_RS09340 (LPH40_09340) | 2274492..2274821 | - | 330 | WP_230428175.1 | GPW/gp25 family protein | - |
| LPH40_RS09345 (LPH40_09345) | 2274922..2275200 | + | 279 | WP_038270683.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LPH40_RS09350 (LPH40_09350) | 2275204..2275503 | + | 300 | WP_081755408.1 | HigA family addiction module antitoxin | Antitoxin |
| LPH40_RS09355 (LPH40_09355) | 2275513..2275809 | - | 297 | WP_230428176.1 | phage baseplate assembly protein V | - |
| LPH40_RS09360 (LPH40_09360) | 2275763..2275972 | - | 210 | WP_230428177.1 | phage baseplate assembly protein V | - |
| LPH40_RS09365 (LPH40_09365) | 2275972..2276625 | - | 654 | WP_230428178.1 | hypothetical protein | - |
| LPH40_RS09370 (LPH40_09370) | 2276601..2277050 | - | 450 | WP_230428179.1 | hypothetical protein | - |
| LPH40_RS09375 (LPH40_09375) | 2277140..2277433 | - | 294 | WP_038270685.1 | hypothetical protein | - |
| LPH40_RS09380 (LPH40_09380) | 2277771..2278019 | - | 249 | WP_038270686.1 | hypothetical protein | - |
| LPH40_RS09385 (LPH40_09385) | 2278058..2279442 | - | 1385 | Protein_1850 | phage major capsid protein | - |
| LPH40_RS09390 (LPH40_09390) | 2279541..2279990 | - | 450 | WP_230428180.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2270155..2295287 | 25132 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10669.11 Da Isoelectric Point: 9.0910
>T225995 WP_038270683.1 NZ_CP087685:2274922-2275200 [Xylella taiwanensis]
MIKTFADQDTESLFNGSRVRRFIHIEAVARRKLIQLHAAATLSFLNAPPGNRLETLKGDRQGQHSIRINNQFRLCFIWEN
GDAYQVEIVDYH
MIKTFADQDTESLFNGSRVRRFIHIEAVARRKLIQLHAAATLSFLNAPPGNRLETLKGDRQGQHSIRINNQFRLCFIWEN
GDAYQVEIVDYH
Download Length: 279 bp
>T225995 NZ_CP121652:2408233-2408643 [Rhizobium sp. CB3171]
ATGTATCTGATCGATACCAATATCATTTCTGAAGCGCGTCGCGGCACTATCGAAGCGATATCCTGGCTGCGCATAGCCGA
CCCGTCGACCGTCTATCTCAGCGTCATCACACTCGGCGAAGTCATGCGCGGGATCGCCCTTAAGCGAAGGACCGATCCAC
GCGCCGCCGCACATCTGGAAGAATGGCTGCGCAAGCTTCGCCACGATCACAGCGGCCGCATCCTGCCAATCACGGACCAA
ATCGCCGTCGAATGGGGCCGCATCTCCGCGCTGCGCCCTCGCGGCGATGCCGACGGGCTGATCGCGGCCACTGCAATCGT
CCATGATCTGATTATCGTTACGCGCAATGTCAGCGATTTTGACGATGCCGGCGTGTCGGTGATCAATCCTTGGGATCAGG
CATCTTACTGA
ATGTATCTGATCGATACCAATATCATTTCTGAAGCGCGTCGCGGCACTATCGAAGCGATATCCTGGCTGCGCATAGCCGA
CCCGTCGACCGTCTATCTCAGCGTCATCACACTCGGCGAAGTCATGCGCGGGATCGCCCTTAAGCGAAGGACCGATCCAC
GCGCCGCCGCACATCTGGAAGAATGGCTGCGCAAGCTTCGCCACGATCACAGCGGCCGCATCCTGCCAATCACGGACCAA
ATCGCCGTCGAATGGGGCCGCATCTCCGCGCTGCGCCCTCGCGGCGATGCCGACGGGCTGATCGCGGCCACTGCAATCGT
CCATGATCTGATTATCGTTACGCGCAATGTCAGCGATTTTGACGATGCCGGCGTGTCGGTGATCAATCCTTGGGATCAGG
CATCTTACTGA
Antitoxin
Download Length: 100 a.a. Molecular weight: 10980.69 Da Isoelectric Point: 9.0879
>AT225995 WP_081755408.1 NZ_CP087685:2275204-2275503 [Xylella taiwanensis]
MSMSKTLPPIHPGEILREEFMAPLGLSSNALAKAIGVTAARINEIVRERRGITADTALRLARYFGTDPQSWLNLEQHYAL
ECAKRDLGEALSRIHPRVA
MSMSKTLPPIHPGEILREEFMAPLGLSSNALAKAIGVTAARINEIVRERRGITADTALRLARYFGTDPQSWLNLEQHYAL
ECAKRDLGEALSRIHPRVA
Download Length: 300 bp
>AT225995 NZ_CP121652:2407979-2408233 [Rhizobium sp. CB3171]
ATGGATTGGCCATTGCAAGACGCCAAGAATCAATTCTCGAAAGTCGTGCAGAAGGCACGCAGCGAAGGTCCGCAAACTGT
GACACTGCGCGGCGAGCGCGCGGTCGTTGTTCTCTCCGCGGAAGACTATGACGCCTTGCGCGCGGGAAAGCCGAGCCTGG
TGGATGATCTGCTATCGGGGCCAGCCTGGGATGACGAGTTGGCTGACGCGGTGACAACGCGAGACAAGACGCCAAGCCGG
GATGTCGCCTTCTGA
ATGGATTGGCCATTGCAAGACGCCAAGAATCAATTCTCGAAAGTCGTGCAGAAGGCACGCAGCGAAGGTCCGCAAACTGT
GACACTGCGCGGCGAGCGCGCGGTCGTTGTTCTCTCCGCGGAAGACTATGACGCCTTGCGCGCGGGAAAGCCGAGCCTGG
TGGATGATCTGCTATCGGGGCCAGCCTGGGATGACGAGTTGGCTGACGCGGTGACAACGCGAGACAAGACGCCAAGCCGG
GATGTCGCCTTCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|