Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | DinJ-YafQ (relBE)/YafQ-RelB |
| Location | 1455113..1455645 | Replicon | chromosome |
| Accession | NZ_CP087683 | ||
| Organism | Xylella taiwanensis strain PLS1135 | ||
Toxin (Protein)
| Gene name | yafQ | Uniprot ID | Z9JHK5 |
| Locus tag | LPH44_RS06390 | Protein ID | WP_038272512.1 |
| Coordinates | 1455113..1455385 (-) | Length | 91 a.a. |
Antitoxin (Protein)
| Gene name | dinJ | Uniprot ID | Z9JHR3 |
| Locus tag | LPH44_RS06395 | Protein ID | WP_038272513.1 |
| Coordinates | 1455385..1455645 (-) | Length | 87 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LPH44_RS06340 (LPH44_06340) | 1451350..1451586 | - | 237 | WP_230428212.1 | major capsid protein | - |
| LPH44_RS06345 (LPH44_06345) | 1451595..1451801 | - | 207 | WP_038273075.1 | hypothetical protein | - |
| LPH44_RS06350 (LPH44_06350) | 1451804..1452118 | - | 315 | WP_230428211.1 | hypothetical protein | - |
| LPH44_RS06355 (LPH44_06355) | 1452394..1452981 | - | 588 | WP_038273076.1 | hypothetical protein | - |
| LPH44_RS06360 (LPH44_06360) | 1453178..1453321 | - | 144 | WP_160165233.1 | hypothetical protein | - |
| LPH44_RS06365 (LPH44_06365) | 1453441..1453641 | - | 201 | WP_038273077.1 | hypothetical protein | - |
| LPH44_RS06370 (LPH44_06370) | 1453690..1453953 | - | 264 | WP_162814095.1 | hypothetical protein | - |
| LPH44_RS06375 (LPH44_06375) | 1453957..1454118 | - | 162 | WP_160165182.1 | hypothetical protein | - |
| LPH44_RS06380 (LPH44_06380) | 1454207..1454674 | + | 468 | WP_162814096.1 | DUF3693 domain-containing protein | - |
| LPH44_RS06385 (LPH44_06385) | 1454733..1455077 | + | 345 | WP_038272511.1 | DUF3653 domain-containing protein | - |
| LPH44_RS06390 (LPH44_06390) | 1455113..1455385 | - | 273 | WP_038272512.1 | type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family | Toxin |
| LPH44_RS06395 (LPH44_06395) | 1455385..1455645 | - | 261 | WP_038272513.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| LPH44_RS06400 (LPH44_06400) | 1455734..1456861 | - | 1128 | WP_114867127.1 | zonular occludens toxin domain-containing protein | - |
| LPH44_RS06405 (LPH44_06405) | 1456874..1457218 | - | 345 | WP_038273069.1 | DUF2523 family protein | - |
| LPH44_RS06410 (LPH44_06410) | 1457221..1458606 | - | 1386 | WP_230428213.1 | furin-like repeat-containing protein | - |
| LPH44_RS06415 (LPH44_06415) | 1458786..1459022 | - | 237 | WP_230428212.1 | major capsid protein | - |
| LPH44_RS06420 (LPH44_06420) | 1459031..1459237 | - | 207 | WP_038273075.1 | hypothetical protein | - |
| LPH44_RS06425 (LPH44_06425) | 1459240..1459554 | - | 315 | WP_230428211.1 | hypothetical protein | - |
| LPH44_RS06430 (LPH44_06430) | 1459830..1460417 | - | 588 | WP_038273076.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 1444933..1470986 | 26053 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 91 a.a. Molecular weight: 10638.26 Da Isoelectric Point: 9.9110
>T225989 WP_038272512.1 NZ_CP087683:c1455385-1455113 [Xylella taiwanensis]
MRRPAYSSQFKRDVRVSQKRGKDIEKLKILITLLIEGSPLPAMYLDHPLKGQWRSFRDAHVEPDWLLIYKVDGDVVRFER
TGRHADLFDD
MRRPAYSSQFKRDVRVSQKRGKDIEKLKILITLLIEGSPLPAMYLDHPLKGQWRSFRDAHVEPDWLLIYKVDGDVVRFER
TGRHADLFDD
Download Length: 273 bp
>T225989 NZ_CP121652:c391097-390828 [Rhizobium sp. CB3171]
GTGGTCTGGACGATTGAGTACGCCCGATCTGCTCGCAAATTCGTTGAAAAACTCGACCCAAAGACACGCAGGAGAATAAG
GGACTTTCTGGAAGAGCGTCTTCCGAGCCTGCACGATCCGCGCCAGGTCGGCGACGCTTTGCAAGGTGCAAAACTCGGAA
ACTATTGGCGTTATCGGGTTGGCGACTATCGGATCATTTGCGATCTGCAGGATAGCCGGCTGGTCGTGTTAGTCGTCGAA
ATCGGCAACCGTCGCGACATCTATCGTTGA
GTGGTCTGGACGATTGAGTACGCCCGATCTGCTCGCAAATTCGTTGAAAAACTCGACCCAAAGACACGCAGGAGAATAAG
GGACTTTCTGGAAGAGCGTCTTCCGAGCCTGCACGATCCGCGCCAGGTCGGCGACGCTTTGCAAGGTGCAAAACTCGGAA
ACTATTGGCGTTATCGGGTTGGCGACTATCGGATCATTTGCGATCTGCAGGATAGCCGGCTGGTCGTGTTAGTCGTCGAA
ATCGGCAACCGTCGCGACATCTATCGTTGA
Antitoxin
Download Length: 87 a.a. Molecular weight: 9440.91 Da Isoelectric Point: 4.8047
>AT225989 WP_038272513.1 NZ_CP087683:c1455645-1455385 [Xylella taiwanensis]
MAANALVRARVDEALKDEAASVLATMGLTVSDLIRITLTKVAREKMLPFEMHSPNRLTVETFVKSECGEDVHYAESADAM
FKDLGI
MAANALVRARVDEALKDEAASVLATMGLTVSDLIRITLTKVAREKMLPFEMHSPNRLTVETFVKSECGEDVHYAESADAM
FKDLGI
Download Length: 261 bp
>AT225989 NZ_CP121652:c391308-391081 [Rhizobium sp. CB3171]
ATGAGCAAGCAGACAGCTATCCGTTTGCCAGATGAGACCTATGAGCGCCTACAGGCTCTGGCCGAACGCACCGGTCGTAC
AGCAACCTACTATATCCGGCAGGCGATTGAAGCACATCTGCAGGACCTGGAGGACGTGTATTTGGCTGAGCGGGCCATGG
AGCGGATTAAGAAGGGCGAAGACGAGATCGTAAGCTCCGAGGAGTTCTGGCGTGGTCTGGACGATTGA
ATGAGCAAGCAGACAGCTATCCGTTTGCCAGATGAGACCTATGAGCGCCTACAGGCTCTGGCCGAACGCACCGGTCGTAC
AGCAACCTACTATATCCGGCAGGCGATTGAAGCACATCTGCAGGACCTGGAGGACGTGTATTTGGCTGAGCGGGCCATGG
AGCGGATTAAGAAGGGCGAAGACGAGATCGTAAGCTCCGAGGAGTTCTGGCGTGGTCTGGACGATTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|