Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/HigB-VapI |
| Location | 904991..905572 | Replicon | chromosome |
| Accession | NZ_CP087683 | ||
| Organism | Xylella taiwanensis strain PLS1135 | ||
Toxin (Protein)
| Gene name | graT | Uniprot ID | Z9JLS9 |
| Locus tag | LPH44_RS03840 | Protein ID | WP_038270683.1 |
| Coordinates | 904991..905269 (+) | Length | 93 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | - |
| Locus tag | LPH44_RS03845 | Protein ID | WP_081755408.1 |
| Coordinates | 905273..905572 (+) | Length | 100 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LPH44_RS03805 (LPH44_03805) | 900272..901318 | + | 1047 | WP_038270717.1 | sulfate/molybdate ABC transporter ATP-binding protein | - |
| LPH44_RS03810 (LPH44_03810) | 902005..902601 | - | 597 | WP_162814073.1 | contractile injection system protein, VgrG/Pvc8 family | - |
| LPH44_RS03815 (LPH44_03815) | 902789..902869 | - | 81 | Protein_741 | tail protein X | - |
| LPH44_RS03820 (LPH44_03820) | 902866..903120 | - | 255 | WP_230428278.1 | phage tail protein | - |
| LPH44_RS03825 (LPH44_03825) | 903193..903675 | - | 483 | Protein_743 | phage tail protein I | - |
| LPH44_RS03830 (LPH44_03830) | 903668..904561 | - | 894 | WP_038270682.1 | baseplate J/gp47 family protein | - |
| LPH44_RS03835 (LPH44_03835) | 904561..904890 | - | 330 | WP_230428175.1 | GPW/gp25 family protein | - |
| LPH44_RS03840 (LPH44_03840) | 904991..905269 | + | 279 | WP_038270683.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LPH44_RS03845 (LPH44_03845) | 905273..905572 | + | 300 | WP_081755408.1 | HigA family addiction module antitoxin | Antitoxin |
| LPH44_RS03850 (LPH44_03850) | 905582..905878 | - | 297 | WP_230428176.1 | phage baseplate assembly protein V | - |
| LPH44_RS03855 (LPH44_03855) | 905832..906041 | - | 210 | WP_230428177.1 | phage baseplate assembly protein V | - |
| LPH44_RS03860 (LPH44_03860) | 906041..906694 | - | 654 | WP_230428178.1 | hypothetical protein | - |
| LPH44_RS03865 (LPH44_03865) | 906670..907119 | - | 450 | WP_230428179.1 | hypothetical protein | - |
| LPH44_RS03870 (LPH44_03870) | 907209..907502 | - | 294 | WP_038270685.1 | hypothetical protein | - |
| LPH44_RS03875 (LPH44_03875) | 907483..907713 | - | 231 | WP_230428500.1 | hypothetical protein | - |
| LPH44_RS03880 (LPH44_03880) | 907840..908088 | - | 249 | WP_038270686.1 | hypothetical protein | - |
| LPH44_RS03885 (LPH44_03885) | 908127..909511 | - | 1385 | Protein_755 | phage major capsid protein | - |
| LPH44_RS03890 (LPH44_03890) | 909610..910059 | - | 450 | WP_230428180.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 900224..925356 | 25132 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10669.11 Da Isoelectric Point: 9.0910
>T225986 WP_038270683.1 NZ_CP087683:904991-905269 [Xylella taiwanensis]
MIKTFADQDTESLFNGSRVRRFIHIEAVARRKLIQLHAAATLSFLNAPPGNRLETLKGDRQGQHSIRINNQFRLCFIWEN
GDAYQVEIVDYH
MIKTFADQDTESLFNGSRVRRFIHIEAVARRKLIQLHAAATLSFLNAPPGNRLETLKGDRQGQHSIRINNQFRLCFIWEN
GDAYQVEIVDYH
Download Length: 279 bp
>T225986 NZ_CP121648:c6815830-6815549 [Methylobacterium nodulans]
ATGATCCAGAGCTTCGCTGACAAGCACGCGCGCGCCCTGCATGAGGATGGCATCTGTCATCCGCGGTGGCGGGCATTCGA
ACGTATCGCCCTGCGCAAGCTCGATGCGCTCGACGCCGCGGTCGACCTCGACGACCTGCGCAGCCCGCCAGGCAATCGTT
TGGAACCTCTCCAGGGCGACCGCGCGGGCCAGCACAGCATTCGCATCAACGACCAATGGCGCATCTGCTTTCGCTGGACA
GACCTCGGTCCCGAGGAGGTCGCGATCGTCGATTATCATTGA
ATGATCCAGAGCTTCGCTGACAAGCACGCGCGCGCCCTGCATGAGGATGGCATCTGTCATCCGCGGTGGCGGGCATTCGA
ACGTATCGCCCTGCGCAAGCTCGATGCGCTCGACGCCGCGGTCGACCTCGACGACCTGCGCAGCCCGCCAGGCAATCGTT
TGGAACCTCTCCAGGGCGACCGCGCGGGCCAGCACAGCATTCGCATCAACGACCAATGGCGCATCTGCTTTCGCTGGACA
GACCTCGGTCCCGAGGAGGTCGCGATCGTCGATTATCATTGA
Antitoxin
Download Length: 100 a.a. Molecular weight: 10980.69 Da Isoelectric Point: 9.0879
>AT225986 WP_081755408.1 NZ_CP087683:905273-905572 [Xylella taiwanensis]
MSMSKTLPPIHPGEILREEFMAPLGLSSNALAKAIGVTAARINEIVRERRGITADTALRLARYFGTDPQSWLNLEQHYAL
ECAKRDLGEALSRIHPRVA
MSMSKTLPPIHPGEILREEFMAPLGLSSNALAKAIGVTAARINEIVRERRGITADTALRLARYFGTDPQSWLNLEQHYAL
ECAKRDLGEALSRIHPRVA
Download Length: 300 bp
>AT225986 NZ_CP121648:c6815534-6815244 [Methylobacterium nodulans]
ATGCCGCGCATCCGCACCCATCCTGGCGAAGTCCTCCTTGAGGACTTCATGAAACCGTTCGGCCTGAGCGCCCGCCAACT
CGCGGAGGCGATCAGGGTGCCGCACAACCGCATCGGCGACATCCTGCGCGAGCGCCGGAGCATCACGGCCGACACGGCCC
TCCGGCTCGGCCGCTACTTCGGCACCACGGCCCAGTTCTGGGTCAACCTCCAGACCGCGCACGATCTCTCGAAGGCGGCG
GCGACGCACGATTACGAGACGATCCGCCCGCGCGAGGCGGCTCCCACCTGA
ATGCCGCGCATCCGCACCCATCCTGGCGAAGTCCTCCTTGAGGACTTCATGAAACCGTTCGGCCTGAGCGCCCGCCAACT
CGCGGAGGCGATCAGGGTGCCGCACAACCGCATCGGCGACATCCTGCGCGAGCGCCGGAGCATCACGGCCGACACGGCCC
TCCGGCTCGGCCGCTACTTCGGCACCACGGCCCAGTTCTGGGTCAACCTCCAGACCGCGCACGATCTCTCGAAGGCGGCG
GCGACGCACGATTACGAGACGATCCGCCCGCGCGAGGCGGCTCCCACCTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|