Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/HigB-VapI |
| Location | 2270976..2271557 | Replicon | chromosome |
| Accession | NZ_CP087681 | ||
| Organism | Xylella taiwanensis strain PLS1133 | ||
Toxin (Protein)
| Gene name | graT | Uniprot ID | Z9JLS9 |
| Locus tag | LPH45_RS09390 | Protein ID | WP_038270683.1 |
| Coordinates | 2270976..2271254 (+) | Length | 93 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | - |
| Locus tag | LPH45_RS09395 | Protein ID | WP_081755408.1 |
| Coordinates | 2271258..2271557 (+) | Length | 100 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LPH45_RS09355 (LPH45_09355) | 2266257..2267303 | + | 1047 | WP_038270717.1 | sulfate/molybdate ABC transporter ATP-binding protein | - |
| LPH45_RS09360 (LPH45_09360) | 2267990..2268586 | - | 597 | WP_162814073.1 | contractile injection system protein, VgrG/Pvc8 family | - |
| LPH45_RS09365 (LPH45_09365) | 2268798..2268854 | - | 57 | Protein_1843 | phage tail protein | - |
| LPH45_RS09370 (LPH45_09370) | 2268851..2269105 | - | 255 | WP_230428278.1 | phage tail protein | - |
| LPH45_RS09375 (LPH45_09375) | 2269178..2269582 | - | 405 | Protein_1845 | phage tail protein I | - |
| LPH45_RS09380 (LPH45_09380) | 2269653..2270546 | - | 894 | WP_038270682.1 | baseplate J/gp47 family protein | - |
| LPH45_RS09385 (LPH45_09385) | 2270546..2270875 | - | 330 | WP_230428175.1 | GPW/gp25 family protein | - |
| LPH45_RS09390 (LPH45_09390) | 2270976..2271254 | + | 279 | WP_038270683.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LPH45_RS09395 (LPH45_09395) | 2271258..2271557 | + | 300 | WP_081755408.1 | HigA family addiction module antitoxin | Antitoxin |
| LPH45_RS09400 (LPH45_09400) | 2271567..2271863 | - | 297 | WP_230428176.1 | phage baseplate assembly protein V | - |
| LPH45_RS09405 (LPH45_09405) | 2271817..2272026 | - | 210 | WP_230428177.1 | phage baseplate assembly protein V | - |
| LPH45_RS09410 (LPH45_09410) | 2272026..2272679 | - | 654 | WP_230428178.1 | hypothetical protein | - |
| LPH45_RS09415 (LPH45_09415) | 2272655..2273104 | - | 450 | WP_230428179.1 | hypothetical protein | - |
| LPH45_RS09420 (LPH45_09420) | 2273194..2273487 | - | 294 | WP_038270685.1 | hypothetical protein | - |
| LPH45_RS09425 (LPH45_09425) | 2273468..2273698 | - | 231 | WP_230428500.1 | hypothetical protein | - |
| LPH45_RS09430 (LPH45_09430) | 2273825..2274073 | - | 249 | WP_038270686.1 | hypothetical protein | - |
| LPH45_RS09435 (LPH45_09435) | 2274112..2275496 | - | 1385 | Protein_1857 | phage major capsid protein | - |
| LPH45_RS09440 (LPH45_09440) | 2275595..2276044 | - | 450 | WP_230428180.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2266209..2291341 | 25132 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10669.11 Da Isoelectric Point: 9.0910
>T225981 WP_038270683.1 NZ_CP087681:2270976-2271254 [Xylella taiwanensis]
MIKTFADQDTESLFNGSRVRRFIHIEAVARRKLIQLHAAATLSFLNAPPGNRLETLKGDRQGQHSIRINNQFRLCFIWEN
GDAYQVEIVDYH
MIKTFADQDTESLFNGSRVRRFIHIEAVARRKLIQLHAAATLSFLNAPPGNRLETLKGDRQGQHSIRINNQFRLCFIWEN
GDAYQVEIVDYH
Download Length: 279 bp
>T225981 NZ_CP121644:c2466406-2465981 [Bradyrhizobium barranii]
GTGAACCTGCTCCTCGACACCAACGTGCTGTCGGAGGTTCAGCGGCCGGCGCCTTCCCCGAAAGTCCTGGCATGGCTCGA
TACGGTCGATGAGGATCGCACGTTCATCAGCGTTGCTTCGATCGCCGAGCTTCGCCGCGGCATCGCCCTGCTGGACGATG
GCCGTCGGCGCGCCGCACTGGTCGCTTGGCTCGCCCATGACCTGCCGGCTCGGTTCGCGCAGCGCATCCTGCCGATCGAC
CACGCGGTCGCTGAGCGCTGGGGCGACCTGATGGCGCAGAGCCGTCGCAATGGCGTTGCGTTGTCCGTGATGGACGGCTT
CTTTGCGGCCACCGCGCTCGCCAACGATCTCACGCTCGTCACACGCAATGTGAAAGATTTTGCGGCCTTCGGCGTTCCGC
TGCTCGACCCATGGAGCGACGCCTAA
GTGAACCTGCTCCTCGACACCAACGTGCTGTCGGAGGTTCAGCGGCCGGCGCCTTCCCCGAAAGTCCTGGCATGGCTCGA
TACGGTCGATGAGGATCGCACGTTCATCAGCGTTGCTTCGATCGCCGAGCTTCGCCGCGGCATCGCCCTGCTGGACGATG
GCCGTCGGCGCGCCGCACTGGTCGCTTGGCTCGCCCATGACCTGCCGGCTCGGTTCGCGCAGCGCATCCTGCCGATCGAC
CACGCGGTCGCTGAGCGCTGGGGCGACCTGATGGCGCAGAGCCGTCGCAATGGCGTTGCGTTGTCCGTGATGGACGGCTT
CTTTGCGGCCACCGCGCTCGCCAACGATCTCACGCTCGTCACACGCAATGTGAAAGATTTTGCGGCCTTCGGCGTTCCGC
TGCTCGACCCATGGAGCGACGCCTAA
Antitoxin
Download Length: 100 a.a. Molecular weight: 10980.69 Da Isoelectric Point: 9.0879
>AT225981 WP_081755408.1 NZ_CP087681:2271258-2271557 [Xylella taiwanensis]
MSMSKTLPPIHPGEILREEFMAPLGLSSNALAKAIGVTAARINEIVRERRGITADTALRLARYFGTDPQSWLNLEQHYAL
ECAKRDLGEALSRIHPRVA
MSMSKTLPPIHPGEILREEFMAPLGLSSNALAKAIGVTAARINEIVRERRGITADTALRLARYFGTDPQSWLNLEQHYAL
ECAKRDLGEALSRIHPRVA
Download Length: 300 bp
>AT225981 NZ_CP121644:c2466684-2466403 [Bradyrhizobium barranii]
ATGACAGACCGCAGCACCGCCCCCGATTCGCCCCCGACTGACACGTGGACGCTCGCCAATGCCAAGGCACGCCTGTCCGA
GGTGGTCGATCGCGCCCAAACTGGCCCCCAGATCATCACCCGACACGGCAGGCCCAATGCGGTTGTCGTTTCCGCGGATG
AATGGGCGCGAAAGACGGCACGCAAAGGCACGCTAGCTGAATTCCTGCTGGCTTCGCCGCTGCGCGGTGCCGACCTCGAA
CTTGAACGGGTGCAGGACGAACCGCGCGACGAGATGCCGTGA
ATGACAGACCGCAGCACCGCCCCCGATTCGCCCCCGACTGACACGTGGACGCTCGCCAATGCCAAGGCACGCCTGTCCGA
GGTGGTCGATCGCGCCCAAACTGGCCCCCAGATCATCACCCGACACGGCAGGCCCAATGCGGTTGTCGTTTCCGCGGATG
AATGGGCGCGAAAGACGGCACGCAAAGGCACGCTAGCTGAATTCCTGCTGGCTTCGCCGCTGCGCGGTGCCGACCTCGAA
CTTGAACGGGTGCAGGACGAACCGCGCGACGAGATGCCGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|