Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/HigB-VapI |
| Location | 518329..518910 | Replicon | chromosome |
| Accession | NZ_CP087680 | ||
| Organism | Xylella taiwanensis strain PLS407 | ||
Toxin (Protein)
| Gene name | graT | Uniprot ID | Z9JLS9 |
| Locus tag | LPH41_RS02425 | Protein ID | WP_038270683.1 |
| Coordinates | 518632..518910 (-) | Length | 93 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | - |
| Locus tag | LPH41_RS02420 | Protein ID | WP_081755408.1 |
| Coordinates | 518329..518628 (-) | Length | 100 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LPH41_RS02380 (LPH41_02380) | 513842..514291 | + | 450 | WP_230428180.1 | hypothetical protein | - |
| LPH41_RS02385 (LPH41_02385) | 514390..515774 | + | 1385 | Protein_467 | phage major capsid protein | - |
| LPH41_RS02390 (LPH41_02390) | 515813..516061 | + | 249 | WP_038270686.1 | hypothetical protein | - |
| LPH41_RS02395 (LPH41_02395) | 516188..516418 | + | 231 | WP_230428500.1 | hypothetical protein | - |
| LPH41_RS02400 (LPH41_02400) | 516399..516692 | + | 294 | WP_038270685.1 | hypothetical protein | - |
| LPH41_RS02405 (LPH41_02405) | 516782..517231 | + | 450 | WP_230428179.1 | hypothetical protein | - |
| LPH41_RS02410 (LPH41_02410) | 517207..517860 | + | 654 | WP_230428178.1 | hypothetical protein | - |
| LPH41_RS11955 | 517860..518069 | + | 210 | WP_230428177.1 | phage baseplate assembly protein V | - |
| LPH41_RS11960 | 518038..518319 | + | 282 | WP_268980389.1 | phage baseplate assembly protein V | - |
| LPH41_RS02420 (LPH41_02420) | 518329..518628 | - | 300 | WP_081755408.1 | HigA family addiction module antitoxin | Antitoxin |
| LPH41_RS02425 (LPH41_02425) | 518632..518910 | - | 279 | WP_038270683.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LPH41_RS02430 (LPH41_02430) | 519011..519340 | + | 330 | WP_230428175.1 | GPW/gp25 family protein | - |
| LPH41_RS02435 (LPH41_02435) | 519340..520233 | + | 894 | WP_038270682.1 | baseplate J/gp47 family protein | - |
| LPH41_RS02440 (LPH41_02440) | 520304..520708 | + | 405 | Protein_479 | phage tail protein I | - |
| LPH41_RS02445 (LPH41_02445) | 520781..521035 | + | 255 | WP_230428278.1 | phage tail protein | - |
| LPH41_RS02450 (LPH41_02450) | 521032..521112 | + | 81 | Protein_481 | tail protein X | - |
| LPH41_RS02455 (LPH41_02455) | 521300..521896 | + | 597 | WP_162814073.1 | contractile injection system protein, VgrG/Pvc8 family | - |
| LPH41_RS02460 (LPH41_02460) | 522583..523629 | - | 1047 | WP_038270717.1 | sulfate/molybdate ABC transporter ATP-binding protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 498545..523677 | 25132 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10669.11 Da Isoelectric Point: 9.0910
>T225974 WP_038270683.1 NZ_CP087680:c518910-518632 [Xylella taiwanensis]
MIKTFADQDTESLFNGSRVRRFIHIEAVARRKLIQLHAAATLSFLNAPPGNRLETLKGDRQGQHSIRINNQFRLCFIWEN
GDAYQVEIVDYH
MIKTFADQDTESLFNGSRVRRFIHIEAVARRKLIQLHAAATLSFLNAPPGNRLETLKGDRQGQHSIRINNQFRLCFIWEN
GDAYQVEIVDYH
Download Length: 279 bp
>T225974 NZ_CP121641:4012688-4012960 [Rhizobium sp. CC1099]
ATGGAACTCGCTGCGGCGGGGCAATTCAGAGCAAAGTGGTCAGATGAGATCCACGATGAATGGACACGAAACGTACTGAA
AAACCGTGACGACCTTACAATTGAGCAACTCGGTCGCACCAAGGATTTGATGAACGCAGCGGTGCCAGACAGTGTGGTCG
ATGGCTATAGTGATCTTGTGCCTGCGCTTGCGCTTCCGGACCCAGACGATTCTAGAGCGTCAGGGGTTACCCAAGACCGT
AGCCGACTGCGGGAATATCTTTTTGCGATTTAG
ATGGAACTCGCTGCGGCGGGGCAATTCAGAGCAAAGTGGTCAGATGAGATCCACGATGAATGGACACGAAACGTACTGAA
AAACCGTGACGACCTTACAATTGAGCAACTCGGTCGCACCAAGGATTTGATGAACGCAGCGGTGCCAGACAGTGTGGTCG
ATGGCTATAGTGATCTTGTGCCTGCGCTTGCGCTTCCGGACCCAGACGATTCTAGAGCGTCAGGGGTTACCCAAGACCGT
AGCCGACTGCGGGAATATCTTTTTGCGATTTAG
Antitoxin
Download Length: 100 a.a. Molecular weight: 10980.69 Da Isoelectric Point: 9.0879
>AT225974 WP_081755408.1 NZ_CP087680:c518628-518329 [Xylella taiwanensis]
MSMSKTLPPIHPGEILREEFMAPLGLSSNALAKAIGVTAARINEIVRERRGITADTALRLARYFGTDPQSWLNLEQHYAL
ECAKRDLGEALSRIHPRVA
MSMSKTLPPIHPGEILREEFMAPLGLSSNALAKAIGVTAARINEIVRERRGITADTALRLARYFGTDPQSWLNLEQHYAL
ECAKRDLGEALSRIHPRVA
Download Length: 300 bp
>AT225974 NZ_CP121641:4012174-4012620 [Rhizobium sp. CC1099]
ATGTCGCAACTGCTAGAACGCCCAATCCTGCCGTCGGCGGACGATACTGAATTGGCCGCCGAGGCCAGTCGCTACATTTC
ACGTGCGAAGCATGAAGGTGCTGAACTTCGAGTTCAAGTTGATGGCGGGGAGCTTCTAAAGCTTCCCAAGGCTGTCAGCG
AGTTACTGTATCATCTCCTAACTGAAATGGCTCAGGGTAATGCTGTAACTTTGATACCCGTCCATGCTGAGCTGACAACT
CAGGAGGCGGCAGATCATCTTAATGTGTCGCGGCCCTACCTGATCAAACTTTTGGAAGAGGGGAAAATCCCATTCCATAT
GGTTGGAAGCCATCGCCGAATAAAGTTTAGCGACCTGGACGGTTTCCGTCGAAAGGCTGAGGACGAAAGAAAACGGCTCA
TGGACGAGCTGGCGAGCCAGGCCCAAGATTTGGGGATGGGCTATTAA
ATGTCGCAACTGCTAGAACGCCCAATCCTGCCGTCGGCGGACGATACTGAATTGGCCGCCGAGGCCAGTCGCTACATTTC
ACGTGCGAAGCATGAAGGTGCTGAACTTCGAGTTCAAGTTGATGGCGGGGAGCTTCTAAAGCTTCCCAAGGCTGTCAGCG
AGTTACTGTATCATCTCCTAACTGAAATGGCTCAGGGTAATGCTGTAACTTTGATACCCGTCCATGCTGAGCTGACAACT
CAGGAGGCGGCAGATCATCTTAATGTGTCGCGGCCCTACCTGATCAAACTTTTGGAAGAGGGGAAAATCCCATTCCATAT
GGTTGGAAGCCATCGCCGAATAAAGTTTAGCGACCTGGACGGTTTCCGTCGAAAGGCTGAGGACGAAAGAAAACGGCTCA
TGGACGAGCTGGCGAGCCAGGCCCAAGATTTGGGGATGGGCTATTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|