Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/HigB-VapI |
| Location | 2274809..2275390 | Replicon | chromosome |
| Accession | NZ_CP087678 | ||
| Organism | Xylella taiwanensis strain PLS206 | ||
Toxin (Protein)
| Gene name | graT | Uniprot ID | Z9JLS9 |
| Locus tag | LPH42_RS09385 | Protein ID | WP_038270683.1 |
| Coordinates | 2274809..2275087 (+) | Length | 93 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | - |
| Locus tag | LPH42_RS09390 | Protein ID | WP_081755408.1 |
| Coordinates | 2275091..2275390 (+) | Length | 100 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LPH42_RS09350 (LPH42_09350) | 2270090..2271136 | + | 1047 | WP_038270717.1 | sulfate/molybdate ABC transporter ATP-binding protein | - |
| LPH42_RS09355 (LPH42_09355) | 2271823..2272419 | - | 597 | WP_162814073.1 | contractile injection system protein, VgrG/Pvc8 family | - |
| LPH42_RS09360 (LPH42_09360) | 2272631..2272687 | - | 57 | Protein_1845 | phage tail protein | - |
| LPH42_RS09365 (LPH42_09365) | 2272684..2272938 | - | 255 | WP_230428278.1 | phage tail protein | - |
| LPH42_RS09370 (LPH42_09370) | 2273011..2273415 | - | 405 | Protein_1847 | phage tail protein I | - |
| LPH42_RS09375 (LPH42_09375) | 2273486..2274379 | - | 894 | WP_038270682.1 | baseplate J/gp47 family protein | - |
| LPH42_RS09380 (LPH42_09380) | 2274379..2274708 | - | 330 | WP_230428175.1 | GPW/gp25 family protein | - |
| LPH42_RS09385 (LPH42_09385) | 2274809..2275087 | + | 279 | WP_038270683.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
| LPH42_RS09390 (LPH42_09390) | 2275091..2275390 | + | 300 | WP_081755408.1 | HigA family addiction module antitoxin | Antitoxin |
| LPH42_RS09395 (LPH42_09395) | 2275400..2275696 | - | 297 | WP_230428176.1 | phage baseplate assembly protein V | - |
| LPH42_RS09400 (LPH42_09400) | 2275650..2275859 | - | 210 | WP_230428177.1 | phage baseplate assembly protein V | - |
| LPH42_RS09405 (LPH42_09405) | 2275859..2276512 | - | 654 | WP_230428178.1 | hypothetical protein | - |
| LPH42_RS09410 (LPH42_09410) | 2276488..2276937 | - | 450 | WP_230428179.1 | hypothetical protein | - |
| LPH42_RS09415 (LPH42_09415) | 2277027..2277320 | - | 294 | WP_038270685.1 | hypothetical protein | - |
| LPH42_RS09420 (LPH42_09420) | 2277658..2277906 | - | 249 | WP_038270686.1 | hypothetical protein | - |
| LPH42_RS09425 (LPH42_09425) | 2277945..2279329 | - | 1385 | Protein_1858 | phage major capsid protein | - |
| LPH42_RS09430 (LPH42_09430) | 2279428..2279877 | - | 450 | WP_230428180.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 2270042..2294345 | 24303 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 93 a.a. Molecular weight: 10669.11 Da Isoelectric Point: 9.0910
>T225968 WP_038270683.1 NZ_CP087678:2274809-2275087 [Xylella taiwanensis]
MIKTFADQDTESLFNGSRVRRFIHIEAVARRKLIQLHAAATLSFLNAPPGNRLETLKGDRQGQHSIRINNQFRLCFIWEN
GDAYQVEIVDYH
MIKTFADQDTESLFNGSRVRRFIHIEAVARRKLIQLHAAATLSFLNAPPGNRLETLKGDRQGQHSIRINNQFRLCFIWEN
GDAYQVEIVDYH
Download Length: 279 bp
>T225968 NZ_CP121636:c167627-167100 [Rhizobium leguminosarum]
GTGACCCTCCCCGTCTGGCATGAAGAGCCGATCGCTAAGTCGCATGATCGGGCCTCATTCGATTGCGGTGATGCGGCAAT
GAACGAGTTCATTCGGCGCTTCGCCCGGCAGAGCCATGAGCAGAATGCGGCGAAAACCTTCTGCGCTATCGACAAGGCCC
ACCCTGATCGCATCCTCGGATTCTACACAGTCGCGCCCTCTGCCGTTACGCATGAGGCCGTGCCTCCGAAGATGACGAGA
GGCCTCGCACGCCATGAAGTCGCAGGCTTCAAGCTCGCGCGCTTGGCAACCGACATAAAGGTGGCGGGAAAAGGTTTAGG
CGGTCAGCTCATCGCTGCTGCAGCGCTCCGTTGCCTGCGGCTCGCCAGCGAGGGCGGCGGGATCCTGCTAATCATCGATG
CCAAGAGCGAGCGCGCCGCCCATTGGTATGCCAGCTACGGCGCCGAACCGCTGCAAGGGAAACCGCTCACCCTCGTTATG
CCGCTTGCCACCTTCGCCGCCGACCTGAAGGCCAAGGGGCTCCTGTAG
GTGACCCTCCCCGTCTGGCATGAAGAGCCGATCGCTAAGTCGCATGATCGGGCCTCATTCGATTGCGGTGATGCGGCAAT
GAACGAGTTCATTCGGCGCTTCGCCCGGCAGAGCCATGAGCAGAATGCGGCGAAAACCTTCTGCGCTATCGACAAGGCCC
ACCCTGATCGCATCCTCGGATTCTACACAGTCGCGCCCTCTGCCGTTACGCATGAGGCCGTGCCTCCGAAGATGACGAGA
GGCCTCGCACGCCATGAAGTCGCAGGCTTCAAGCTCGCGCGCTTGGCAACCGACATAAAGGTGGCGGGAAAAGGTTTAGG
CGGTCAGCTCATCGCTGCTGCAGCGCTCCGTTGCCTGCGGCTCGCCAGCGAGGGCGGCGGGATCCTGCTAATCATCGATG
CCAAGAGCGAGCGCGCCGCCCATTGGTATGCCAGCTACGGCGCCGAACCGCTGCAAGGGAAACCGCTCACCCTCGTTATG
CCGCTTGCCACCTTCGCCGCCGACCTGAAGGCCAAGGGGCTCCTGTAG
Antitoxin
Download Length: 100 a.a. Molecular weight: 10980.69 Da Isoelectric Point: 9.0879
>AT225968 WP_081755408.1 NZ_CP087678:2275091-2275390 [Xylella taiwanensis]
MSMSKTLPPIHPGEILREEFMAPLGLSSNALAKAIGVTAARINEIVRERRGITADTALRLARYFGTDPQSWLNLEQHYAL
ECAKRDLGEALSRIHPRVA
MSMSKTLPPIHPGEILREEFMAPLGLSSNALAKAIGVTAARINEIVRERRGITADTALRLARYFGTDPQSWLNLEQHYAL
ECAKRDLGEALSRIHPRVA
Download Length: 300 bp
>AT225968 NZ_CP121636:c167902-167624 [Rhizobium leguminosarum]
ATGCCGAGAACCGCGGACAATAAATCCGAACGCTACCAGCTGCGCATCCCGCCAAAGCAGAAGGCAATGATCGCGCGCGC
AGCTGCCCTTTCGAACAAGGATATGGCCGATTTCATTCTCGATAAGATAGTACCTGAAGCCGAAGCCGTCATCCAGGCTG
CTGAAGTTGAGACCGTTTCGAGCCGCGATTTCATCCGCATCCTCGACCTGCTTGAACGCCCGCCCAAACCAAACGCGAGA
CTACGCGCCGCGATCTCTGCTCTACCGGATGCCTTGTGA
ATGCCGAGAACCGCGGACAATAAATCCGAACGCTACCAGCTGCGCATCCCGCCAAAGCAGAAGGCAATGATCGCGCGCGC
AGCTGCCCTTTCGAACAAGGATATGGCCGATTTCATTCTCGATAAGATAGTACCTGAAGCCGAAGCCGTCATCCAGGCTG
CTGAAGTTGAGACCGTTTCGAGCCGCGATTTCATCCGCATCCTCGACCTGCTTGAACGCCCGCCCAAACCAAACGCGAGA
CTACGCGCCGCGATCTCTGCTCTACCGGATGCCTTGTGA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|