Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | DinJ-YafQ (relBE)/YafQ-RelB |
| Location | 38443..38975 | Replicon | chromosome |
| Accession | NZ_CP087676 | ||
| Organism | Xylella taiwanensis strain PLS396 | ||
Toxin (Protein)
| Gene name | yafQ | Uniprot ID | Z9JHK5 |
| Locus tag | LPH43_RS00225 | Protein ID | WP_038272512.1 |
| Coordinates | 38443..38715 (-) | Length | 91 a.a. |
Antitoxin (Protein)
| Gene name | dinJ | Uniprot ID | Z9JHR3 |
| Locus tag | LPH43_RS00230 | Protein ID | WP_038272513.1 |
| Coordinates | 38715..38975 (-) | Length | 87 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LPH43_RS00175 (LPH43_00175) | 34680..34916 | - | 237 | WP_230428212.1 | major capsid protein | - |
| LPH43_RS00180 (LPH43_00180) | 34925..35131 | - | 207 | WP_038273075.1 | hypothetical protein | - |
| LPH43_RS00185 (LPH43_00185) | 35134..35448 | - | 315 | WP_230428211.1 | hypothetical protein | - |
| LPH43_RS00190 (LPH43_00190) | 35724..36311 | - | 588 | WP_038273076.1 | hypothetical protein | - |
| LPH43_RS00195 (LPH43_00195) | 36508..36651 | - | 144 | WP_160165233.1 | hypothetical protein | - |
| LPH43_RS00200 (LPH43_00200) | 36771..36971 | - | 201 | WP_038273077.1 | hypothetical protein | - |
| LPH43_RS00205 (LPH43_00205) | 37020..37283 | - | 264 | WP_162814095.1 | hypothetical protein | - |
| LPH43_RS00210 (LPH43_00210) | 37287..37448 | - | 162 | WP_160165182.1 | hypothetical protein | - |
| LPH43_RS00215 (LPH43_00215) | 37519..38004 | + | 486 | WP_114867129.1 | DUF3693 domain-containing protein | - |
| LPH43_RS00220 (LPH43_00220) | 38063..38407 | + | 345 | WP_038272511.1 | DUF3653 domain-containing protein | - |
| LPH43_RS00225 (LPH43_00225) | 38443..38715 | - | 273 | WP_038272512.1 | type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family | Toxin |
| LPH43_RS00230 (LPH43_00230) | 38715..38975 | - | 261 | WP_038272513.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
| LPH43_RS00235 (LPH43_00235) | 39064..40191 | - | 1128 | WP_114867127.1 | zonular occludens toxin domain-containing protein | - |
| LPH43_RS00240 (LPH43_00240) | 40204..40548 | - | 345 | WP_038273069.1 | DUF2523 family protein | - |
| LPH43_RS00245 (LPH43_00245) | 40551..41936 | - | 1386 | WP_230428213.1 | furin-like repeat-containing protein | - |
| LPH43_RS00250 (LPH43_00250) | 42116..42352 | - | 237 | WP_230428212.1 | major capsid protein | - |
| LPH43_RS00255 (LPH43_00255) | 42361..42567 | - | 207 | WP_038273075.1 | hypothetical protein | - |
| LPH43_RS00260 (LPH43_00260) | 42570..42884 | - | 315 | WP_230428211.1 | hypothetical protein | - |
| LPH43_RS00265 (LPH43_00265) | 43160..43747 | - | 588 | WP_038273076.1 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | Prophage | - | - | 10285..54316 | 44031 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 91 a.a. Molecular weight: 10638.26 Da Isoelectric Point: 9.9110
>T225955 WP_038272512.1 NZ_CP087676:c38715-38443 [Xylella taiwanensis]
MRRPAYSSQFKRDVRVSQKRGKDIEKLKILITLLIEGSPLPAMYLDHPLKGQWRSFRDAHVEPDWLLIYKVDGDVVRFER
TGRHADLFDD
MRRPAYSSQFKRDVRVSQKRGKDIEKLKILITLLIEGSPLPAMYLDHPLKGQWRSFRDAHVEPDWLLIYKVDGDVVRFER
TGRHADLFDD
Download Length: 273 bp
>T225955 NZ_CP121625:3242020-3242409 [Acinetobacter baumannii]
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AGTTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATAAGTCACAGAACACCGTT
TCTCGCGTCAAAATTTTAAAAATAATTGATTGTCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA
TTGATCAACCATTTGAATTTTAAGCTGAAATATAGTCGTTTTTCGATTATATTTCAGTTTTTTATTGGCTTAAGCTTAGC
AGTTCTATTTTATCAATTAATGCCGTTACTATGGTGGTTAGTTGTAATCAGCTTACTATTTATCAGCTTTATTTTCTTTT
TAAAGCGTCCGCAGCTTGCACAAATTGCTTATTTAGATAAAAAACTATGGTCGCTTGCTTATAAGTCACAGAACACCGTT
TCTCGCGTCAAAATTTTAAAAATAATTGATTGTCAGATTTTCATAGTGATCTATTTTGAAGGTCATAAAACACTAACTTC
TATCATTTGGTTTGATCAAATGTCATTAGCAGAGTGGAAAAAGCTTAAAACTTTAGAAAAACTCTATTAA
Antitoxin
Download Length: 87 a.a. Molecular weight: 9440.91 Da Isoelectric Point: 4.8047
>AT225955 WP_038272513.1 NZ_CP087676:c38975-38715 [Xylella taiwanensis]
MAANALVRARVDEALKDEAASVLATMGLTVSDLIRITLTKVAREKMLPFEMHSPNRLTVETFVKSECGEDVHYAESADAM
FKDLGI
MAANALVRARVDEALKDEAASVLATMGLTVSDLIRITLTKVAREKMLPFEMHSPNRLTVETFVKSECGEDVHYAESADAM
FKDLGI
Download Length: 261 bp
>AT225955 NZ_CP121625:3241756-3242013 [Acinetobacter baumannii]
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAG
ACCCTGATTTACTAGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTTCATGGTTAA
ATGTCTGAAGAAATGACCTTGGAAGAACGTAAAGTAATCTATCGCGCACGTCGTGGTTTAAAGGAAATTGATGTCTATTT
TGACCCTTATGTGAAAAATTATTATTTAAAGGCAGACCCGGCAGAAAAAGCGTTGTTTGCTGAGTTGGTAGAACAGGAAG
ACCCTGATTTACTAGATTGGTTTATGGAAGTATCAGAACCACCACGTACCGAATTACGTGACTTTATCTATAAATTAAAA
CACTATGTTCATGGTTAA
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|