Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 1162838..1163493 Replicon chromosome
Accession NZ_CP087204
Organism Pseudomonas sp. B21-054

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag LOY70_RS04980 Protein ID WP_092223719.1
Coordinates 1162838..1163182 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag LOY70_RS04985 Protein ID WP_123342704.1
Coordinates 1163179..1163493 (+) Length 105 a.a.

Genomic Context


LOY70_RS04955LOY70_RS04960LOY70_RS04965LOY70_RS04970LOY70_RS04975LOY70_RS04980LOY70_RS04985LOY70_RS04990LOY70_RS04995LOY70_RS05000LOY70_RS05005
Location: 1157851..1158798 (948 bp)
Type: Others
Protein ID: WP_025211924.1
Location: 1158802..1160832 (2031 bp)
Type: Others
Protein ID: WP_123415447.1
Location: 1160836..1161462 (627 bp)
Type: Others
Protein ID: WP_025211926.1
Location: 1161463..1161798 (336 bp)
Type: Others
Protein ID: WP_025211927.1
Location: 1161810..1162697 (888 bp)
Type: Others
Protein ID: WP_025211928.1
Location: 1162838..1163182 (345 bp)
Type: Toxin
Protein ID: WP_092223719.1
Location: 1163179..1163493 (315 bp)
Type: Antitoxin
Protein ID: WP_123342704.1
Location: 1163684..1164388 (705 bp)
Type: Others
Protein ID: WP_265033853.1
Location: 1164528..1165271 (744 bp)
Type: Others
Protein ID: WP_265033855.1
Location: 1165364..1166377 (1014 bp)
Type: Others
Protein ID: WP_265033857.1
Location: 1166507..1167424 (918 bp)
Type: Others
Protein ID: WP_265033859.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
LOY70_RS04955 (LOY70_04950)1157851..1158798+948WP_025211924.1ubiquinol oxidase subunit II-
LOY70_RS04960 (LOY70_04955)1158802..1160832+2031WP_123415447.1cytochrome o ubiquinol oxidase subunit I-
LOY70_RS04965 (LOY70_04960)1160836..1161462+627WP_025211926.1cytochrome o ubiquinol oxidase subunit III-
LOY70_RS04970 (LOY70_04965)1161463..1161798+336WP_025211927.1cytochrome o ubiquinol oxidase subunit IV-
LOY70_RS04975 (LOY70_04970)1161810..1162697+888WP_025211928.1heme o synthase-
LOY70_RS04980 (LOY70_04975)1162838..1163182+345WP_092223719.1toxinToxin
LOY70_RS04985 (LOY70_04980)1163179..1163493+315WP_123342704.1helix-turn-helix domain-containing proteinAntitoxin
LOY70_RS04990 (LOY70_04985)1163684..1164388-705WP_265033853.1hypothetical protein-
LOY70_RS04995 (LOY70_04990)1164528..1165271-744WP_265033855.1DUF72 domain-containing protein-
LOY70_RS05000 (LOY70_04995)1165364..1166377-1014WP_265033857.1sensor domain-containing diguanylate cyclase-
LOY70_RS05005 (LOY70_05000)1166507..1167424-918WP_265033859.1LysR family transcriptional regulator-

Associated MGEs


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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
No matching records found


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

(42-94)


Sequences


Toxin        


Download         Length: 115 a.a.        Molecular weight: 13709.71 Da        Isoelectric Point: 9.2887

>T225134 WP_092223719.1 NZ_CP087204:1162838-1163182 [Pseudomonas sp. B21-054]
MRTLFFETTTFTATVGHYLTDDEYRLLQSYMLQHPEVGDVMPRTGGFRKLRWFDERRGKGKRGGLRVIYYWLMNDRQFWM
FAIYDKDELENLTSEQEKTLKRAIEAELKVRGTL

Download         Length: 345 bp

>T225134 NZ_CP121003:825262-825675 [Salmonella enterica]
GTGGTCCTGTGGCAATCTGATTTACGCGTCTCATGGCGCGCTCAGTGGATCTCATTGCTCATTCATGGGCTGGTTGCCGC
GGTGATTTTATTGATGCCCTGGCCGCTGAGTTATACCCCGTTATGGATGATACTACTGTCGCTGGTCGTGTTTGACTGTG
TACGTAGCCAGCGCAGGATTAATACCTGCCAGGGAGAGATCAAGCTACTCATGGACGGGCGCTTACGCTGGCAGGGGCAG
GACTGGACGCTCTTGCGTCCGCCCTGGTTACTGAAGAGCGGGATGGTGTTGCGTTTACGCGCAGAGTCTGGACGTCATCA
GCATTTATGGCTGGCGGCGGATAGCATGGAAGAAGCGGAATGGCGTGAGTTGCGTCGGATACTGTTACAGCAGCCGATAT
CAGGCCAACACTAA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11718.70 Da        Isoelectric Point: 10.2441

>AT225134 WP_123342704.1 NZ_CP087204:1163179-1163493 [Pseudomonas sp. B21-054]
MKKRDLFAEMMQGVGEMAAQREGKITLRQISIEDKPVPEVSAQEIVALRDKLHMSQAVFAKSIRTSPGTLRNWEQEKSKP
NAQAALLIRLVEKFPDMVERLGAV

Download         Length: 315 bp

>AT225134 NZ_CP121003:825015-825281 [Salmonella enterica]
ATGGATATTCACAATAAAGCACGTATTCACTGGGCATGTCGTCGCGGTATGCGCGAACTTGATATTTCCATCATGCCGTT
TTTTGAACATGAGTACGATAGTTTAAGTGATGAAGAAAAGCGTATTTTTGTCCGTTTGTTGCAGAGTGACGACCCGGATT
TATTTAACTGGTTAATGAATCACGGTAAACCGGCTGACGCTGAACTGGAACAGATGGTCCGACTCATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins


Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures


Toxin

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Source
ID
Structure
No matching records found


Antitoxin

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Source
ID
Structure
No matching records found

References