Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 1162838..1163493 Replicon chromosome
Accession NZ_CP087204
Organism Pseudomonas sp. B21-054

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag LOY70_RS04980 Protein ID WP_092223719.1
Coordinates 1162838..1163182 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag LOY70_RS04985 Protein ID WP_123342704.1
Coordinates 1163179..1163493 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY70_RS04955 (LOY70_04950) 1157851..1158798 + 948 WP_025211924.1 ubiquinol oxidase subunit II -
LOY70_RS04960 (LOY70_04955) 1158802..1160832 + 2031 WP_123415447.1 cytochrome o ubiquinol oxidase subunit I -
LOY70_RS04965 (LOY70_04960) 1160836..1161462 + 627 WP_025211926.1 cytochrome o ubiquinol oxidase subunit III -
LOY70_RS04970 (LOY70_04965) 1161463..1161798 + 336 WP_025211927.1 cytochrome o ubiquinol oxidase subunit IV -
LOY70_RS04975 (LOY70_04970) 1161810..1162697 + 888 WP_025211928.1 heme o synthase -
LOY70_RS04980 (LOY70_04975) 1162838..1163182 + 345 WP_092223719.1 toxin Toxin
LOY70_RS04985 (LOY70_04980) 1163179..1163493 + 315 WP_123342704.1 helix-turn-helix domain-containing protein Antitoxin
LOY70_RS04990 (LOY70_04985) 1163684..1164388 - 705 WP_265033853.1 hypothetical protein -
LOY70_RS04995 (LOY70_04990) 1164528..1165271 - 744 WP_265033855.1 DUF72 domain-containing protein -
LOY70_RS05000 (LOY70_04995) 1165364..1166377 - 1014 WP_265033857.1 sensor domain-containing diguanylate cyclase -
LOY70_RS05005 (LOY70_05000) 1166507..1167424 - 918 WP_265033859.1 LysR family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(42-94)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13709.71 Da        Isoelectric Point: 9.2887

>T225134 WP_092223719.1 NZ_CP087204:1162838-1163182 [Pseudomonas sp. B21-054]
MRTLFFETTTFTATVGHYLTDDEYRLLQSYMLQHPEVGDVMPRTGGFRKLRWFDERRGKGKRGGLRVIYYWLMNDRQFWM
FAIYDKDELENLTSEQEKTLKRAIEAELKVRGTL

Download         Length: 345 bp

>T225134 NZ_CP121003:825262-825675 [Salmonella enterica]
GTGGTCCTGTGGCAATCTGATTTACGCGTCTCATGGCGCGCTCAGTGGATCTCATTGCTCATTCATGGGCTGGTTGCCGC
GGTGATTTTATTGATGCCCTGGCCGCTGAGTTATACCCCGTTATGGATGATACTACTGTCGCTGGTCGTGTTTGACTGTG
TACGTAGCCAGCGCAGGATTAATACCTGCCAGGGAGAGATCAAGCTACTCATGGACGGGCGCTTACGCTGGCAGGGGCAG
GACTGGACGCTCTTGCGTCCGCCCTGGTTACTGAAGAGCGGGATGGTGTTGCGTTTACGCGCAGAGTCTGGACGTCATCA
GCATTTATGGCTGGCGGCGGATAGCATGGAAGAAGCGGAATGGCGTGAGTTGCGTCGGATACTGTTACAGCAGCCGATAT
CAGGCCAACACTAA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11718.70 Da        Isoelectric Point: 10.2441

>AT225134 WP_123342704.1 NZ_CP087204:1163179-1163493 [Pseudomonas sp. B21-054]
MKKRDLFAEMMQGVGEMAAQREGKITLRQISIEDKPVPEVSAQEIVALRDKLHMSQAVFAKSIRTSPGTLRNWEQEKSKP
NAQAALLIRLVEKFPDMVERLGAV

Download         Length: 315 bp

>AT225134 NZ_CP121003:825015-825281 [Salmonella enterica]
ATGGATATTCACAATAAAGCACGTATTCACTGGGCATGTCGTCGCGGTATGCGCGAACTTGATATTTCCATCATGCCGTT
TTTTGAACATGAGTACGATAGTTTAAGTGATGAAGAAAAGCGTATTTTTGTCCGTTTGTTGCAGAGTGACGACCCGGATT
TATTTAACTGGTTAATGAATCACGGTAAACCGGCTGACGCTGAACTGGAACAGATGGTCCGACTCATTCAGACACGGAAT
CGGGAACGTGGTCCTGTGGCAATCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References