Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4410996..4411650 Replicon chromosome
Accession NZ_CP087201
Organism Pseudomonas sp. B21-059

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag LOY69_RS19410 Protein ID WP_207166232.1
Coordinates 4410996..4411346 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag LOY69_RS19415 Protein ID WP_102864712.1
Coordinates 4411333..4411650 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY69_RS19400 (LOY69_19350) 4407755..4409287 + 1533 WP_011062195.1 NADH-quinone oxidoreductase subunit M -
LOY69_RS19405 (LOY69_19355) 4409295..4410758 + 1464 WP_015636299.1 NADH-quinone oxidoreductase subunit NuoN -
LOY69_RS19410 (LOY69_19360) 4410996..4411346 + 351 WP_207166232.1 toxin Toxin
LOY69_RS19415 (LOY69_19365) 4411333..4411650 + 318 WP_102864712.1 transcriptional regulator Antitoxin
LOY69_RS19420 (LOY69_19370) 4411719..4413101 - 1383 WP_102881792.1 cysteine--tRNA ligase -
LOY69_RS19425 (LOY69_19375) 4413120..4414820 - 1701 WP_265073449.1 glutamine--tRNA ligase/YqeY domain fusion protein -
LOY69_RS19430 (LOY69_19380) 4415091..4415594 + 504 WP_016965727.1 peptidylprolyl isomerase -
LOY69_RS19435 (LOY69_19385) 4415591..4416343 + 753 WP_102864709.1 UDP-2,3-diacylglucosamine diphosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(48-101)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13966.06 Da        Isoelectric Point: 8.9805

>T225124 WP_207166232.1 NZ_CP087201:4410996-4411346 [Pseudomonas sp. B21-059]
MNALFIELPAFARYRKDFLDDELFCELQIELLRHPHAGVLIQGTGGLRKMRFVDERRNKGRRGGLRVVYYWWSGGAQFWL
FTLFDKEQMDDLLPQQRQQLKQLLEREIEARRHDQT

Download         Length: 351 bp

>T225124 NZ_CP120978:2670518-2670772 [Moellerella wisconsensis]
GTGAAGCTAACATGGTCTGCCGAAGCATGGGAAGATTACTTGTACTGGCAAGAAACGGACAGAAAAACCGTAAAAAAGAT
AAATGAGCTCATTAAGAATGCCAGTAGAACACCATTTGAAGGAAAAGGTAAACCTGAACCTCTGAAACACAATCTTGCTG
GGTTCTGGTCACGAAGAATTACGGCGGAACATCGATTAGTCTATGCCGTTAGTAATGATTCCTTGCTAATAGCATCATGT
CGTTATCACTACTGA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 12086.93 Da        Isoelectric Point: 10.4439

>AT225124 WP_102864712.1 NZ_CP087201:4411333-4411650 [Pseudomonas sp. B21-059]
MTKRDIFSELVEGIDALTQERQGKITLRSHKVKLDKLPPITATEVMNIRQQLNLSRSVFAMYLRTNTRTLENWEQGRATP
NAQATTLMRLVERYPDTVERLASLA

Download         Length: 318 bp

>AT225124 NZ_CP120978:2670270-2670521 [Moellerella wisconsensis]
ATGAAAGCGGTAAGCTACAGTGAAGCCAGACAGAATTTATCAACAACAATGATTCAAACAGTTGAAGATAGAGTACCAGT
ACTGATCACGCGCCAGAATGGCGAATCATGTGTACTGATGTCTCTCGATGAATATAACTCTCTCGAAGAGACGGCATACC
TAATGAGATCACCAAAAAATGCACGCAGACTTATGGACTCGATAGAAAGCCTAAAAGATGGAAAAGGGATGGAAAGGGAA
ATTATTAAGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References