Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 1126385..1127040 Replicon chromosome
Accession NZ_CP087200
Organism Pseudomonas viciae strain B21-062

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag LOY66_RS04815 Protein ID WP_265072716.1
Coordinates 1126385..1126729 (+) Length 115 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag LOY66_RS04820 Protein ID WP_122567030.1
Coordinates 1126726..1127040 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY66_RS04790 (LOY66_04785) 1121400..1122347 + 948 WP_256454288.1 ubiquinol oxidase subunit II -
LOY66_RS04795 (LOY66_04790) 1122351..1124381 + 2031 WP_135843774.1 cytochrome o ubiquinol oxidase subunit I -
LOY66_RS04800 (LOY66_04795) 1124385..1125011 + 627 WP_135843775.1 cytochrome o ubiquinol oxidase subunit III -
LOY66_RS04805 (LOY66_04800) 1125012..1125347 + 336 WP_025211927.1 cytochrome o ubiquinol oxidase subunit IV -
LOY66_RS04810 (LOY66_04805) 1125359..1126246 + 888 WP_135843776.1 heme o synthase -
LOY66_RS04815 (LOY66_04810) 1126385..1126729 + 345 WP_265072716.1 toxin Toxin
LOY66_RS04820 (LOY66_04815) 1126726..1127040 + 315 WP_122567030.1 helix-turn-helix domain-containing protein Antitoxin
LOY66_RS04825 (LOY66_04820) 1127149..1127853 - 705 WP_135843778.1 hypothetical protein -
LOY66_RS04830 (LOY66_04825) 1128013..1129026 - 1014 WP_135843779.1 sensor domain-containing diguanylate cyclase -
LOY66_RS04835 (LOY66_04830) 1129126..1130043 - 918 WP_265072717.1 LysR family transcriptional regulator -
LOY66_RS04840 (LOY66_04835) 1130142..1131317 + 1176 WP_265072718.1 aspartate aminotransferase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(42-94)


Sequences

Toxin        


Download         Length: 115 a.a.        Molecular weight: 13683.63 Da        Isoelectric Point: 9.2887

>T225116 WP_265072716.1 NZ_CP087200:1126385-1126729 [Pseudomonas viciae]
MRTLFFETTTFTATVGHYLTDDEYRLLQSYMLQHPEVGDVMPRTGGFRKLRWFDERRGKGKRGGLRVIYYWLMNDRQFWM
FAIYDKDELENLTSEQEKTLKRAIEAELKVRGTS

Download         Length: 345 bp

>T225116 NZ_CP120974:2876695-2876919 [Moellerella wisconsensis]
ATGAATGAAAGACAGGAAAATATGACTAAAACAGACTATCTGATGCGTTTAAGAAAATGCACGACTATTGAAACATTAGA
GCGTGTTATTGAAAAAAATAAATATGAGCTATCTGATGATGAACTCGAACTGTTTTTTTCCGCTGCTGACCATCGTCTAG
CAGAACTAACAATGAATAAACTGTATGACAAAATTCCAGCATCTGTCTGGAAATATGTTCGATAA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11743.71 Da        Isoelectric Point: 9.8409

>AT225116 WP_122567030.1 NZ_CP087200:1126726-1127040 [Pseudomonas viciae]
MKKRDLFAEMMQGVEEMAAHREGKITLRQISIEDKPAPEVSAQEIVALRDKLHMSQAVFAKSIRTSPGTLRNWEQEKSKP
NAQAALLIKLVEKFPDMVERLGAV

Download         Length: 315 bp

>AT225116 NZ_CP120974:2876280-2876648 [Moellerella wisconsensis]
ATGGATGAATATTCACCCAGATATTACGATACTGCTGAATTAAAGTATTTATGTGATAGCCTTAACAATGATGCGATATT
ATCGCTACATAAGACTAAAACGCATTGGATTAATGATTTAAGTTCACAGCAAAGTACGAATTTGAATGAGTTAATAGAGC
ATGTGGCTGCATTTTTTTGGAAATTTAAGATAAAATACCCTAGTGAACGCTTAGTCATCTCTCTAGTTGATGAATATCTT
GATGAAACTTATAATTTATTTGGTAGTCCATTAATCACATTAAATGAATTTTCAGATTGGCAAAAAATGAATACTCACTT
AATTGATGAATTAAATAACGATTTAAAGTGTTCAGTAGCCAAACTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References