Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | higBA (relBE)/- |
| Location | 5428799..5429453 | Replicon | chromosome |
| Accession | NZ_CP087197 | ||
| Organism | Pseudomonas sp. B21-012 | ||
Toxin (Protein)
| Gene name | higB | Uniprot ID | - |
| Locus tag | LOY37_RS24995 | Protein ID | WP_258715940.1 |
| Coordinates | 5428799..5429137 (+) | Length | 113 a.a. |
Antitoxin (Protein)
| Gene name | higA | Uniprot ID | - |
| Locus tag | LOY37_RS25000 | Protein ID | WP_258608324.1 |
| Coordinates | 5429139..5429453 (+) | Length | 105 a.a. |
Genomic Context
Location: 5427308..5428126 (819 bp)
Type: Others
Protein ID: WP_258715939.1
Type: Others
Protein ID: WP_258715939.1
Location: 5428219..5428680 (462 bp)
Type: Others
Protein ID: WP_038998420.1
Type: Others
Protein ID: WP_038998420.1
Location: 5428799..5429137 (339 bp)
Type: Toxin
Protein ID: WP_258715940.1
Type: Toxin
Protein ID: WP_258715940.1
Location: 5429139..5429453 (315 bp)
Type: Antitoxin
Protein ID: WP_258608324.1
Type: Antitoxin
Protein ID: WP_258608324.1
Location: 5429614..5431296 (1683 bp)
Type: Others
Protein ID: WP_045199243.1
Type: Others
Protein ID: WP_045199243.1
Location: 5431310..5432107 (798 bp)
Type: Others
Protein ID: WP_093378922.1
Type: Others
Protein ID: WP_093378922.1
Location: 5425694..5426116 (423 bp)
Type: Others
Protein ID: WP_258715937.1
Type: Others
Protein ID: WP_258715937.1
Location: 5426185..5426358 (174 bp)
Type: Others
Protein ID: WP_258717225.1
Type: Others
Protein ID: WP_258717225.1
Location: 5426426..5427214 (789 bp)
Type: Others
Protein ID: WP_258715938.1
Type: Others
Protein ID: WP_258715938.1
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Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| LOY37_RS24970 (LOY37_24945) | 5425694..5426116 | - | 423 | WP_258715937.1 | type II toxin-antitoxin system HicB family antitoxin | - |
| LOY37_RS24975 (LOY37_24950) | 5426185..5426358 | - | 174 | WP_258717225.1 | type II toxin-antitoxin system HicA family toxin | - |
| LOY37_RS24980 (LOY37_24955) | 5426426..5427214 | - | 789 | WP_258715938.1 | helix-turn-helix transcriptional regulator | - |
| LOY37_RS24985 (LOY37_24960) | 5427308..5428126 | + | 819 | WP_258715939.1 | 3-methyl-2-oxobutanoate hydroxymethyltransferase | - |
| LOY37_RS24990 (LOY37_24965) | 5428219..5428680 | + | 462 | WP_038998420.1 | Lrp/AsnC family transcriptional regulator | - |
| LOY37_RS24995 (LOY37_24970) | 5428799..5429137 | + | 339 | WP_258715940.1 | toxin | Toxin |
| LOY37_RS25000 (LOY37_24975) | 5429139..5429453 | + | 315 | WP_258608324.1 | transcriptional regulator | Antitoxin |
| LOY37_RS25005 (LOY37_24980) | 5429614..5431296 | + | 1683 | WP_045199243.1 | NAD(P)/FAD-dependent oxidoreductase | - |
| LOY37_RS25010 (LOY37_24985) | 5431310..5432107 | + | 798 | WP_093378922.1 | carbon-nitrogen hydrolase family protein | - |
Associated MGEs
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MGE detail | Similar MGEs | Relative position | MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| No matching records found | |||||||
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 113 a.a. Molecular weight: 13043.94 Da Isoelectric Point: 9.7600
>T225107 WP_258715940.1 NZ_CP087197:5428799-5429137 [Pseudomonas sp. B21-012]
MDALFVELPAFARYRSDYLDDEAMRALQLVLLLNPQAGSVIQGTGGLRKVRFADDQRHKGKRGGIRVIYYWWSNGQQFWL
FTLYGKDQLDDLSPAQRHSLKQMLDLQIEARR
MDALFVELPAFARYRSDYLDDEAMRALQLVLLLNPQAGSVIQGTGGLRKVRFADDQRHKGKRGGIRVIYYWWSNGQQFWL
FTLYGKDQLDDLSPAQRHSLKQMLDLQIEARR
Download Length: 339 bp
>T225107 NZ_CP120970:2876834-2877058 [Moellerella wisconsensis]
ATGAATGAAAGACAGGAAAATATGACTAAAACAGACTATCTGATGCGTTTAAGAAAATGCACGACTATTGAAACATTAGA
GCGTGTTATTGAAAAAAATAAATATGAGCTATCTGATGATGAACTCGAACTGTTTTTTTCCGCTGCTGACCATCGTCTAG
CAGAACTAACAATGAATAAACTGTATGACAAAATTCCAGCATCTGTCTGGAAATATGTTCGATAA
ATGAATGAAAGACAGGAAAATATGACTAAAACAGACTATCTGATGCGTTTAAGAAAATGCACGACTATTGAAACATTAGA
GCGTGTTATTGAAAAAAATAAATATGAGCTATCTGATGATGAACTCGAACTGTTTTTTTCCGCTGCTGACCATCGTCTAG
CAGAACTAACAATGAATAAACTGTATGACAAAATTCCAGCATCTGTCTGGAAATATGTTCGATAA
Antitoxin
Download Length: 105 a.a. Molecular weight: 11941.75 Da Isoelectric Point: 7.2065
>AT225107 WP_258608324.1 NZ_CP087197:5429139-5429453 [Pseudomonas sp. B21-012]
MKRDVFSELNEGFDALAQERQGKLTLRSHKVQLAELMDVSAEELVAIRERLNMSRAVFAMYLRTNARTLENWEQGRARPN
AQAMTLIRLVEKFPETVEHLAALA
MKRDVFSELNEGFDALAQERQGKLTLRSHKVQLAELMDVSAEELVAIRERLNMSRAVFAMYLRTNARTLENWEQGRARPN
AQAMTLIRLVEKFPETVEHLAALA
Download Length: 315 bp
>AT225107 NZ_CP120970:2876419-2876787 [Moellerella wisconsensis]
ATGGATGAATATTCACCCAGATATTACGATACTGCTGAATTAAAGTATTTATGTGATAGCCTTAACAATGATGCGATATT
ATCGCTACATAAGACTAAAACGCATTGGATTAATGATTTAAGTTCACAGCAAAGTACGAATTTGAATGAGTTAATAGAGC
ATGTGGCTGCATTTTTTTGGAAATTTAAGATAAAATACCCTAGTGAACGCTTAGTCATCTCTCTAGTTGATGAATATCTT
GATGAAACTTATAATTTATTTGGTAGTCCATTAATCACATTAAATGAATTTTCAGATTGGCAAAAAATGAATACTCACTT
AATTGATGAATTAAATAACGATTTAAAGTGTTCAGTAGCCAAACTATGA
ATGGATGAATATTCACCCAGATATTACGATACTGCTGAATTAAAGTATTTATGTGATAGCCTTAACAATGATGCGATATT
ATCGCTACATAAGACTAAAACGCATTGGATTAATGATTTAAGTTCACAGCAAAGTACGAATTTGAATGAGTTAATAGAGC
ATGTGGCTGCATTTTTTTGGAAATTTAAGATAAAATACCCTAGTGAACGCTTAGTCATCTCTCTAGTTGATGAATATCTT
GATGAAACTTATAATTTATTTGGTAGTCCATTAATCACATTAAATGAATTTTCAGATTGGCAAAAAATGAATACTCACTT
AATTGATGAATTAAATAACGATTTAAAGTGTTCAGTAGCCAAACTATGA