Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4228935..4229589 Replicon chromosome
Accession NZ_CP087194
Organism Pseudomonas sp. B21-017

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag LOY28_RS19120 Protein ID WP_064621318.1
Coordinates 4228935..4229285 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag LOY28_RS19125 Protein ID WP_007940887.1
Coordinates 4229275..4229589 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY28_RS19100 (LOY28_19085) 4224510..4226042 + 1533 WP_018925506.1 NADH-quinone oxidoreductase subunit M -
LOY28_RS19105 (LOY28_19090) 4226050..4227513 + 1464 WP_018925505.1 NADH-quinone oxidoreductase subunit NuoN -
LOY28_RS19110 (LOY28_19095) 4227683..4227970 + 288 WP_258612364.1 type II toxin-antitoxin system prevent-host-death family antitoxin -
LOY28_RS19115 (LOY28_19100) 4228095..4228559 - 465 WP_258612365.1 GNAT family N-acetyltransferase -
LOY28_RS19120 (LOY28_19105) 4228935..4229285 + 351 WP_064621318.1 hypothetical protein Toxin
LOY28_RS19125 (LOY28_19110) 4229275..4229589 + 315 WP_007940887.1 transcriptional regulator Antitoxin
LOY28_RS19130 (LOY28_19115) 4229766..4231091 + 1326 WP_258612366.1 OprD family porin -
LOY28_RS19135 (LOY28_19120) 4231637..4231969 - 333 WP_018925501.1 DUF2790 domain-containing protein -
LOY28_RS19140 (LOY28_19125) 4232048..4232248 - 201 WP_064618798.1 co-regulatory protein PtrA N-terminal domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13896.58 Da        Isoelectric Point: 6.7293

>T225096 WP_064621318.1 NZ_CP087194:4228935-4229285 [Pseudomonas sp. B21-017]
MDALFIELPAFQKHRDDYLDDDLFHSFQLELLKNPEAGDLIEGTGGLRKIRFSDQRRGKGKRSGLRVIYYWWSGFDQFWL
FTVYSKNEQDDLSPSQKKLFRQTLDREINTRTHYET

Download         Length: 351 bp

>T225096 NZ_CP120958:2334711-2335448 [Bacillus cereus]
ATGATCTCTAACATTCGAATTGGCTTATTTGTTTTAGCGATTGTCTTTGTAGTCCTTGTTTTCTTTTATTGGAAAAATGA
GGAGTTGTACGAGGAGAAAAAGCAACGTATTAGAAAGACTTGGTATGGTTTGTTTATCATATCTGTCACCGTGTATTTCA
TGATAAAAGGAATTGATTTAACCCTCTGGAAAAATCTTTTAATGTTTACTGCAATGGTTATTTTTGTTGATATTGCGTTC
ATTTTAACGCCTAATATTTCAGAAATATGGGGTGCGAAATTTAGCGATATTGGCAAGACAGTTCAATCAATAAAACGATC
ATTAATTGCATCTAAAGCGAGAGGGGAAATATACACGACAATTATTCAAAATGTTAATCCAGCAGTATTCGGTACGATGG
AATGGCATACGGAAGAGGAATATACAAAGAGCTTAAATGCATTTTTAGATTCATATGGGGAAAAGATTGGCGCGAAAATT
GTTGTTTTTGAAGCCGCGAAAGAGTTAAATACAAACTTTCGTGGTATTCGCTCGCAATTTAGTATTATCGTTCCGTTAGA
ACATATCGAGCAATTGAATGAGCAGAAAGCGGTGCAAGTAGAAAATGTCGGGATTATACCAGCAAAAATAGTAAGTGACG
TTTTCATTGTTATTGATGGAAAGAAAAATAACCTGCAAGATCGGGATTTTGAAAATGTATATAATTTAACAATACATCAT
AGTTATTTTAGTAAATAA

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11904.82 Da        Isoelectric Point: 10.3437

>AT225096 WP_007940887.1 NZ_CP087194:4229275-4229589 [Pseudomonas sp. B21-017]
MKRDIFSELMEGLEALADERQGKVTLRTHKVKLPKLVPITAEEVVAIRQQLNLSRSVFAMYLRTNTRTLENWEQGRATPN
AQATTLIRLVERFPQTIEQLAALT

Download         Length: 315 bp

>AT225096 NZ_CP120958:2335561-2335689 [Bacillus cereus]
GTGGTAAAAGATTATGACAATGATTTTTTTAAAGAAGGTAACGAAGATACAACAGATTTCTCTTTAATAAAAGGGGATAC
GTTGCAGCAAGTAGAAGAATTAGAAGAAGAATTAAAAAGAAAATCATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References