Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) prlF-yhaV (relBE)/YhaV-PrlF
Location 982797..983617 Replicon chromosome
Accession NZ_CP087190
Organism Pseudomonas sp. B21-023

Toxin (Protein)


Gene name yhaV Uniprot ID -
Locus tag LOY42_RS04525 Protein ID WP_258599911.1
Coordinates 982797..983294 (-) Length 166 a.a.

Antitoxin (Protein)


Gene name prlF Uniprot ID -
Locus tag LOY42_RS04530 Protein ID WP_258599913.1
Coordinates 983291..983617 (-) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY42_RS04505 (LOY42_04510) 977976..979502 + 1527 WP_139668940.1 efflux transporter outer membrane subunit -
LOY42_RS04510 (LOY42_04515) 979499..981676 + 2178 WP_258599909.1 FUSC family protein -
LOY42_RS04515 (LOY42_04520) 981681..981881 + 201 WP_008097766.1 DUF1656 domain-containing protein -
LOY42_RS04520 (LOY42_04525) 981892..982752 + 861 WP_139668944.1 HlyD family secretion protein -
LOY42_RS04525 (LOY42_04530) 982797..983294 - 498 WP_258599911.1 type II toxin-antitoxin system YhaV family toxin Toxin
LOY42_RS04530 (LOY42_04535) 983291..983617 - 327 WP_258599913.1 type II toxin-antitoxin system PrlF family antitoxin Antitoxin
LOY42_RS04535 (LOY42_04540) 983727..984173 - 447 WP_139668950.1 universal stress protein -
LOY42_RS04540 (LOY42_04545) 984434..985339 + 906 WP_102682106.1 LysR family transcriptional regulator -
LOY42_RS04545 (LOY42_04550) 985618..987159 + 1542 WP_102682105.1 MFS transporter -
LOY42_RS04550 (LOY42_04555) 987187..988248 + 1062 WP_102682104.1 HlyD family secretion protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin endonuclease, YhaV

(16-152)

Antitoxin

PrlF antitoxin

(8-106)


Sequences

Toxin        


Download         Length: 166 a.a.        Molecular weight: 19024.80 Da        Isoelectric Point: 10.2683

>T225085 WP_258599911.1 NZ_CP087190:c983294-982797 [Pseudomonas sp. B21-023]
MTETRRKPLCVHGWSVFAHPLFLDKLEALIDKVEVLQRKDPVGYVKKNAAKRLKAIRGLAFDVIAQAPGNPDHRMGGTLG
AEHKHWFRAKFFQQYRLFFRYHASSKIIVLAWVDDDDSKRAYESSDDAYRVFRRMLGNGHPPDDWDQLLQEAAAATARFN
ATLKR

Download         Length: 498 bp

>T225085 NZ_CP120948:2366799-2367098 [Burkholderia contaminans]
ATGGACAAGATCAGCACCCGGCCGTGGGATTCGGCCGATCATCTGAAAACCGAAGACGACATGGCCGACTACTTCGAAGC
GTGCCTGCAGGAAGCCGGCGACGATCCGGCCTTCATCGCGCATGCGCTCGGCGTGATCGCGCGTGCACGCGGCATGTCGC
AGGTCGCGCGCGATGCGGGCCTGTCGCGCGAAGGGCTGTACAAGGCGCTGTCGCACGACGGCAACCCCAGCTTCGGCACG
ATCCTGAAGGTCATCAAGGCGCTCGGCCTGCAACTGCACGGCTCGAAAGCGCACGCATGA

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 12165.62 Da        Isoelectric Point: 4.2225

>AT225085 WP_258599913.1 NZ_CP087190:c983617-983291 [Pseudomonas sp. B21-023]
MATTFEAESTLTERYQTTVPETVRRALGLKKRDKIHYSIRPDGAVILTRAETAEEDPAVGQFLEFLEREIATNPQRLKVV
DAEFFARLDALVGDVEIDLDQPLSADDE

Download         Length: 327 bp

>AT225085 NZ_CP120948:2366457-2366795 [Burkholderia contaminans]
ATGGTTGACATACTGCAATCCATGCCCTACAGTGCGCCTACGTTCAGCATCCGGACCACCGGCGTCTTCGACACCTGGTT
TGCCGGCCTGCAGGATCGCGTCGCGAAGCGCCGCATCCAGGCACGCATCGACCGCCTCTCGATGGGCAATCCGGGCGACT
GGAAGTCCGCCGGCTCGCCGGTCGTCGAGATGCGGATCGACCACGGCCCGGGCTATCGCGTCTACTACGTCCGGCGCGGA
ACGATCTGGGTCATCCTGCTCTGCGGCGGCGATAAATCGTCGCAACAGGCCGACATCCGCGCCGCGCACGCGATGCTCGC
GCATCTCGACATGGAGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References