Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | mqsRA (relBE)/MqsR-MqsA |
Location | 4155647..4156347 | Replicon | chromosome |
Accession | NZ_CP087185 | ||
Organism | Pseudomonas sichuanensis strain B21-027 |
Toxin (Protein)
Gene name | mqsR | Uniprot ID | - |
Locus tag | LOY51_RS18870 | Protein ID | WP_258642575.1 |
Coordinates | 4156051..4156347 (-) | Length | 99 a.a. |
Antitoxin (Protein)
Gene name | mqsA | Uniprot ID | - |
Locus tag | LOY51_RS18865 | Protein ID | WP_125859468.1 |
Coordinates | 4155647..4156048 (-) | Length | 134 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
LOY51_RS18845 (LOY51_18815) | 4150791..4151612 | - | 822 | WP_125464896.1 | transporter substrate-binding domain-containing protein | - |
LOY51_RS18850 (LOY51_18820) | 4151697..4152626 | - | 930 | WP_125464897.1 | FAD-binding protein | - |
LOY51_RS18855 (LOY51_18825) | 4152627..4153376 | - | 750 | WP_125464898.1 | electron transfer flavoprotein subunit beta/FixA family protein | - |
LOY51_RS18860 (LOY51_18830) | 4153905..4155587 | + | 1683 | WP_125464899.1 | electron transfer flavoprotein-ubiquinone oxidoreductase | - |
LOY51_RS18865 (LOY51_18835) | 4155647..4156048 | - | 402 | WP_125859468.1 | type II toxin-antitoxin system MqsA family antitoxin | Antitoxin |
LOY51_RS18870 (LOY51_18840) | 4156051..4156347 | - | 297 | WP_258642575.1 | type II toxin-antitoxin system MqsR family toxin | Toxin |
LOY51_RS18875 (LOY51_18845) | 4156442..4157767 | - | 1326 | WP_258642576.1 | MFS transporter | - |
LOY51_RS18880 (LOY51_18850) | 4157829..4158314 | - | 486 | WP_125464903.1 | histidine kinase | - |
LOY51_RS18885 (LOY51_18855) | 4158483..4158959 | - | 477 | WP_125464904.1 | sigma-70 family RNA polymerase sigma factor | - |
LOY51_RS18890 (LOY51_18860) | 4159178..4160353 | + | 1176 | WP_258642578.1 | efflux RND transporter periplasmic adaptor subunit | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 99 a.a. Molecular weight: 11237.21 Da Isoelectric Point: 8.9903
>T225049 WP_258642575.1 NZ_CP087185:c4156347-4156051 [Pseudomonas sichuanensis]
MEKRVPHCPLDRVKALLAVKRISPTFAALRGARSLGLDYPGMLDVISSLERTDFYKSMTCYTEHRVWQDIYRPLTAVGYV
YLKLSVVDDVLIVSFKEL
MEKRVPHCPLDRVKALLAVKRISPTFAALRGARSLGLDYPGMLDVISSLERTDFYKSMTCYTEHRVWQDIYRPLTAVGYV
YLKLSVVDDVLIVSFKEL
Download Length: 297 bp
>T225049 NZ_CP120942:c2171053-2170799 [Aeromonas caviae]
ATGAGATTAATTTTTTCCGATGATGCATGGGAAGATTATCTGTTCTGGCAAAAACAAGACCGCCGCATGGTTGATCGAAT
TAACAAGCTAATTAAAGAAACCACCCGAGAGCCTTTCTCTGGAGTGGGCAAGCCAGAGCCATTAAAACATGCTTTGGCCG
GTTATTGGTCTCGTCGAATTACGGATGAGCACCGAATGGTTTACAAAGTGGCGGATGATGCCCTTTGGATCGTTCAACTC
AAGTACCACTACTGA
ATGAGATTAATTTTTTCCGATGATGCATGGGAAGATTATCTGTTCTGGCAAAAACAAGACCGCCGCATGGTTGATCGAAT
TAACAAGCTAATTAAAGAAACCACCCGAGAGCCTTTCTCTGGAGTGGGCAAGCCAGAGCCATTAAAACATGCTTTGGCCG
GTTATTGGTCTCGTCGAATTACGGATGAGCACCGAATGGTTTACAAAGTGGCGGATGATGCCCTTTGGATCGTTCAACTC
AAGTACCACTACTGA
Antitoxin
Download Length: 134 a.a. Molecular weight: 14632.61 Da Isoelectric Point: 4.9775
>AT225049 WP_125859468.1 NZ_CP087185:c4156048-4155647 [Pseudomonas sichuanensis]
MRCPICGGAELAPDIQDMPYRYKGESTLIQGVSGDYCSACGEAVLSHDEAMRVSEQMSAFERRVNAAAVDPAFISAVRKK
FDLDQREAGEIFGGGVNAFSRYENGKTTPPVALIKLFKLLDRHPELFEEVRTA
MRCPICGGAELAPDIQDMPYRYKGESTLIQGVSGDYCSACGEAVLSHDEAMRVSEQMSAFERRVNAAAVDPAFISAVRKK
FDLDQREAGEIFGGGVNAFSRYENGKTTPPVALIKLFKLLDRHPELFEEVRTA
Download Length: 402 bp
>AT225049 NZ_CP120942:c2171301-2171050 [Aeromonas caviae]
ATGGACGCTATCACTTACACACACGCCCGCGCCAACCTGGCTGGAACCATGGATCGTGTTTGCAACGATCATGAGCCGGT
GATCATCACACGTAACGGCGACCAATCGGTTGTGATTCTCTCGCTGGAAGATTTCCAGGCGCTGGAAGAAACTGCGTATC
TGCTGCGCAGCCCCGCCAACGCCAAGCGGCTTTTCAAGTCGATCGAGCAACTTGAAGCGGGCCGAGGACAGGCGCGGGAG
TTGGCCGAATGA
ATGGACGCTATCACTTACACACACGCCCGCGCCAACCTGGCTGGAACCATGGATCGTGTTTGCAACGATCATGAGCCGGT
GATCATCACACGTAACGGCGACCAATCGGTTGTGATTCTCTCGCTGGAAGATTTCCAGGCGCTGGAAGAAACTGCGTATC
TGCTGCGCAGCCCCGCCAACGCCAAGCGGCTTTTCAAGTCGATCGAGCAACTTGAAGCGGGCCGAGGACAGGCGCGGGAG
TTGGCCGAATGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|
Antitoxin
Source | ID | Structure |
---|