Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) mqsRA (relBE)/MqsR-MqsA
Location 4155647..4156347 Replicon chromosome
Accession NZ_CP087185
Organism Pseudomonas sichuanensis strain B21-027

Toxin (Protein)


Gene name mqsR Uniprot ID -
Locus tag LOY51_RS18870 Protein ID WP_258642575.1
Coordinates 4156051..4156347 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name mqsA Uniprot ID -
Locus tag LOY51_RS18865 Protein ID WP_125859468.1
Coordinates 4155647..4156048 (-) Length 134 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY51_RS18845 (LOY51_18815) 4150791..4151612 - 822 WP_125464896.1 transporter substrate-binding domain-containing protein -
LOY51_RS18850 (LOY51_18820) 4151697..4152626 - 930 WP_125464897.1 FAD-binding protein -
LOY51_RS18855 (LOY51_18825) 4152627..4153376 - 750 WP_125464898.1 electron transfer flavoprotein subunit beta/FixA family protein -
LOY51_RS18860 (LOY51_18830) 4153905..4155587 + 1683 WP_125464899.1 electron transfer flavoprotein-ubiquinone oxidoreductase -
LOY51_RS18865 (LOY51_18835) 4155647..4156048 - 402 WP_125859468.1 type II toxin-antitoxin system MqsA family antitoxin Antitoxin
LOY51_RS18870 (LOY51_18840) 4156051..4156347 - 297 WP_258642575.1 type II toxin-antitoxin system MqsR family toxin Toxin
LOY51_RS18875 (LOY51_18845) 4156442..4157767 - 1326 WP_258642576.1 MFS transporter -
LOY51_RS18880 (LOY51_18850) 4157829..4158314 - 486 WP_125464903.1 histidine kinase -
LOY51_RS18885 (LOY51_18855) 4158483..4158959 - 477 WP_125464904.1 sigma-70 family RNA polymerase sigma factor -
LOY51_RS18890 (LOY51_18860) 4159178..4160353 + 1176 WP_258642578.1 efflux RND transporter periplasmic adaptor subunit -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains


Predicted by InterproScan

Toxin

(6-97)

Antitoxin

(1-131)


Sequences


Toxin        


Download         Length: 99 a.a.        Molecular weight: 11237.21 Da        Isoelectric Point: 8.9903

>T225049 WP_258642575.1 NZ_CP087185:c4156347-4156051 [Pseudomonas sichuanensis]
MEKRVPHCPLDRVKALLAVKRISPTFAALRGARSLGLDYPGMLDVISSLERTDFYKSMTCYTEHRVWQDIYRPLTAVGYV
YLKLSVVDDVLIVSFKEL

Download         Length: 297 bp

>T225049 NZ_CP120942:c2171053-2170799 [Aeromonas caviae]
ATGAGATTAATTTTTTCCGATGATGCATGGGAAGATTATCTGTTCTGGCAAAAACAAGACCGCCGCATGGTTGATCGAAT
TAACAAGCTAATTAAAGAAACCACCCGAGAGCCTTTCTCTGGAGTGGGCAAGCCAGAGCCATTAAAACATGCTTTGGCCG
GTTATTGGTCTCGTCGAATTACGGATGAGCACCGAATGGTTTACAAAGTGGCGGATGATGCCCTTTGGATCGTTCAACTC
AAGTACCACTACTGA

Antitoxin


Download         Length: 134 a.a.        Molecular weight: 14632.61 Da        Isoelectric Point: 4.9775

>AT225049 WP_125859468.1 NZ_CP087185:c4156048-4155647 [Pseudomonas sichuanensis]
MRCPICGGAELAPDIQDMPYRYKGESTLIQGVSGDYCSACGEAVLSHDEAMRVSEQMSAFERRVNAAAVDPAFISAVRKK
FDLDQREAGEIFGGGVNAFSRYENGKTTPPVALIKLFKLLDRHPELFEEVRTA

Download         Length: 402 bp

>AT225049 NZ_CP120942:c2171301-2171050 [Aeromonas caviae]
ATGGACGCTATCACTTACACACACGCCCGCGCCAACCTGGCTGGAACCATGGATCGTGTTTGCAACGATCATGAGCCGGT
GATCATCACACGTAACGGCGACCAATCGGTTGTGATTCTCTCGCTGGAAGATTTCCAGGCGCTGGAAGAAACTGCGTATC
TGCTGCGCAGCCCCGCCAACGCCAAGCGGCTTTTCAAGTCGATCGAGCAACTTGAAGCGGGCCGAGGACAGGCGCGGGAG
TTGGCCGAATGA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure


Antitoxin

Source ID Structure

References