225034

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 4616645..4617299 Replicon chromosome
Accession NZ_CP087182
Organism Pseudomonas protegens strain B21-030

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag LOY23_RS20980 Protein ID WP_053152689.1
Coordinates 4616645..4616995 (+) Length 117 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag LOY23_RS20985 Protein ID WP_053152691.1
Coordinates 4616982..4617299 (+) Length 106 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY23_RS20970 (LOY23_20940) 4613404..4614936 + 1533 WP_015636298.1 NADH-quinone oxidoreductase subunit M -
LOY23_RS20975 (LOY23_20945) 4614944..4616407 + 1464 WP_011062196.1 NADH-quinone oxidoreductase subunit NuoN -
LOY23_RS20980 (LOY23_20950) 4616645..4616995 + 351 WP_053152689.1 hypothetical protein Toxin
LOY23_RS20985 (LOY23_20955) 4616982..4617299 + 318 WP_053152691.1 transcriptional regulator Antitoxin
LOY23_RS20990 (LOY23_20960) 4617368..4618750 - 1383 WP_053159449.1 cysteine--tRNA ligase -
LOY23_RS20995 (LOY23_20965) 4618769..4620469 - 1701 WP_174395733.1 glutamine--tRNA ligase/YqeY domain fusion protein -
LOY23_RS21000 (LOY23_20970) 4620740..4621243 + 504 WP_011062201.1 peptidylprolyl isomerase -
LOY23_RS21005 (LOY23_20975) 4621240..4621992 + 753 WP_011062202.1 UDP-2,3-diacylglucosamine diphosphatase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(48-101)


Sequences

Toxin        


Download         Length: 117 a.a.        Molecular weight: 13936.07 Da        Isoelectric Point: 9.6226

>T225034 WP_053152689.1 NZ_CP087182:4616645-4616995 [Pseudomonas protegens]
MNALFIELPAFARYRKGFLDDELFCELQIELLRHPHAGVLIQGTGGLRKMRFIDERRNKGRRGGLRVIYYWWSGGAQFWL
FTLFDKEQMDDLLPQQRQQLKQLLEREIEARRHDQT

Download         Length: 351 bp

>T225034 NZ_CP120847:c4003506-4003189 [Klebsiella pneumoniae]
ATGTTCAGATTGGTTGTGCATGTGGACGTTAAAAAGGAATTGCAGGCGCTTCCGCCCATTGTCCAGGCGAAGATGATCCG
GCAATTAGACAAGTTACGCCAAAATCCCACCGCGCTGAGAGAACCTGACAGTAAACCGCTGGGGCAGGGGCTATTTGAAA
TTCGTGCGTTAGGTTCGGTACAGGGGCGAGGGATCTACGTTTTTCAGCAAGGCAAAACGCTCTTTCTGCTACGGGTTTTT
GTCAAGAAAACGCAAAAAACCCCGTCATCGGAAATTCGCCTGGCGCTGAAGCGATTAGAGGAGATGCGCAATGAGTAA

Antitoxin


Download         Length: 106 a.a.        Molecular weight: 12050.92 Da        Isoelectric Point: 10.4439

>AT225034 WP_053152691.1 NZ_CP087182:4616982-4617299 [Pseudomonas protegens]
MTKRDIFSELVEGIDALTQERQGKITLRSHKVKLDKLPPITAAEVMNIRQQLNLSRSVFAMYLRTNTRTLENWEQGRAIP
NAQATTLIRLVERYPDTVERLASLA

Download         Length: 318 bp

>AT225034 NZ_CP120847:c4003196-4002909 [Klebsiella pneumoniae]
ATGAGTAAAAAGATCATTGACTGGGATACGTTAAAAACAGAACTGCTTGGCCAGCCTGAGGTTCAGGCTGCATTCGATGC
GCAAGAACGTCAACAGCGATTACGTACTATGCTGGCGCAATGGCGCGAGCAGGCGGGGCTAACCCGAGCCCAGGTGGCGC
AGAGGATGGGGGTGAGTGCGCCGACAGTCTCCAGAATGGAAGCCAATATCACCCGCGCCAGTCTGGATACCTTAACGCGA
TACGCGTTAGCCTGCGGTATAAAGCACCCGCAAGTTTTACTTTACTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References