225024

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) higBA (relBE)/-
Location 5410014..5410668 Replicon chromosome
Accession NZ_CP087180
Organism Pseudomonas sp. B21-032

Toxin (Protein)


Gene name higB Uniprot ID -
Locus tag LOY54_RS25070 Protein ID WP_258608322.1
Coordinates 5410014..5410352 (+) Length 113 a.a.

Antitoxin (Protein)


Gene name higA Uniprot ID -
Locus tag LOY54_RS25075 Protein ID WP_258608324.1
Coordinates 5410354..5410668 (+) Length 105 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LOY54_RS25055 (LOY54_25030) 5407642..5408430 - 789 WP_258608318.1 helix-turn-helix transcriptional regulator -
LOY54_RS25060 (LOY54_25035) 5408524..5409342 + 819 WP_258608320.1 3-methyl-2-oxobutanoate hydroxymethyltransferase -
LOY54_RS25065 (LOY54_25040) 5409435..5409896 + 462 WP_038998420.1 Lrp/AsnC family transcriptional regulator -
LOY54_RS25070 (LOY54_25045) 5410014..5410352 + 339 WP_258608322.1 toxin Toxin
LOY54_RS25075 (LOY54_25050) 5410354..5410668 + 315 WP_258608324.1 transcriptional regulator Antitoxin
LOY54_RS25080 (LOY54_25055) 5410829..5412511 + 1683 WP_258608333.1 NAD(P)/FAD-dependent oxidoreductase -
LOY54_RS25085 (LOY54_25060) 5412525..5413322 + 798 WP_093378922.1 carbon-nitrogen hydrolase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin


No domain identified.


Antitoxin

Cro/C1-type helix-turn-helix domain

(41-100)


Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 13091.98 Da        Isoelectric Point: 9.7600

>T225024 WP_258608322.1 NZ_CP087180:5410014-5410352 [Pseudomonas sp. B21-032]
MEALFVELPAFARYRSDYLDDEAMRALQFVLLLNPQAGSVIQGTGGLRKVRFADDQRHKGKRGGIRVIYYWWSNGQQFWL
FTLYGKDQLDDLSPAQRHSLKQMLDLQIEARR

Download         Length: 339 bp

>T225024 NZ_CP120837:c4488956-4488645 [Salmonella enterica subsp. enterica]
ATGCAATTTATAGAAACGGAACTCTTTACTGAAGATGTTAAAAAACTGCTCGATGAGGATGAATACCATAAGCTTCAGGT
TTTTATGGCTCAGCATCCAGATTGTGGTGATGTCATTCAGGAAACGGGCGGCCTGAGAAAAATGCGCTGGGGAGCGCGAG
GCAAAGGAAAGCGTAGTGGCGTGCGAATTATCTATTTTCACCGTAGTCAACGGTATGAGATTCGCTTGCTTCTGATTTAT
CAAAAAGGCATTAAAGATGATCTCACGCCGCAGGAAAAAGCGGTGCTTCGTATGCTGAATGAGAGGTGGTAG

Antitoxin


Download         Length: 105 a.a.        Molecular weight: 11941.75 Da        Isoelectric Point: 7.2065

>AT225024 WP_258608324.1 NZ_CP087180:5410354-5410668 [Pseudomonas sp. B21-032]
MKRDVFSELNEGFDALAQERQGKLTLRSHKVQLAELMDVSAEELVAIRERLNMSRAVFAMYLRTNARTLENWEQGRARPN
AQAMTLIRLVEKFPETVEHLAALA

Download         Length: 315 bp

>AT225024 NZ_CP120837:c4488644-4488354 [Salmonella enterica subsp. enterica]
ATGGATAAAGTGTTATTTGAGCGATTAACTCAAAGTATGTCTCAAATGAATGAAATCATTGAAGGGACCCGTGAGCCTTC
TCGTACCTTTCATATTGATGCAATGAAGATTAAAGAAATACGGCAGGCATCTGGGTTGTCGCAATCTAAGTTTGCAGAAC
TGATTTCGGTCAACGTGGATACGCTGCGCAACTGGGAGCAAGGAAGACGTTCACCGACAGGGCCAGCCAAAGCGTTACTT
CGCGCCATTGCCAACGACCCGAGAAACGTTATACAAGCATTGCGTTATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References